Research uncovers gene variant role in disease biology
New research has filled in missing links between gene variants that have been implicated in disease through genome-wide…
African American ancestry study identifies new lung cancer risk factors
Cancer Despite having lower smoking habits than other groups in the U.S., Black Americans are more likely to…
Psychiatric Disorders and Brain Structure Connected via Genetic Mapping
Credit: Floaria Bicher / iStock / Getty Images Plus Researchers have long hypothesized that the genes influencing the…
LDAK-KVIK performs fast and powerful mixed-model association analysis of quantitative and binary phenotypes
Uffelmann, E. et al. Genome-wide association studies. Nat. Rev. Methods Prim. 1, 59 (2021). CAS Google Scholar Visscher,…
Parent-of-origin effects on complex traits in up to 236,781 individuals
UK Biobank genotype processing We used the UK Biobank Axiom Array data provided in PLINK format39 and converted…
Towards improved fine-mapping of candidate causal variants
Visscher, P. M. et al. 10 years of GWAS discovery: biology, function, and translation. Am. J. Hum. Genet.…
Large-scale genome-wide analyses of stuttering
Yairi, E. & Ambrose, N. Epidemiology of stuttering: 21st century advances. J. Fluen. Disord. 38, 66–87 (2013). Google…
Combined genome-wide association study of facial traits in Europeans increases explained variance and improves prediction
C-GWAS and replication highlight 62 novel face loci The C-GWAS discovery phase included 11,662 individuals of European descent…