Unmasking the hyperactive circuitry of early Alzheimer’s
Neuroscientists at King’s College London have pinpointed a mechanism behind the increased neural connectivity observed in the very early stages of Alzheimer’s…
How somatic mutations shape disease and reveal new drug targets
Scientists reveal how evolution within our own tissues can drive disease, protect cells, and uncover hidden therapeutic targets…
Study reveals ATM kinase as the key driver of replicative senescence
After a finite number of divisions, cells simply give up. As each round of replication trims their telomeres-the…
What happens when microplastics reach the testes? Study shows autophagy and cell loss
Invisible plastic fragments from common tableware are turning up in semen; now, researchers reveal how nanoscale particles may…
How plant compounds could target Alzheimer’s disease from multiple angles
Scientists reveal how plant-based compounds may combat Alzheimer’s through multi-target actions, but poor bioavailability and the blood-brain barrier…
Metformin’s blood sugar control starts in the brain, not just the liver, study finds
Scientists uncover how low-dose metformin targets brain pathways to lower blood sugar, opening fresh avenues for safer and…