Depression’s “Energy Crisis”: Fatigue Starts at the Cellular Level
Summary: Fatigue is one of the most debilitating and hardest-to-treat symptoms of major depressive disorder (MDD). New research…
New CRISPR technique boosts mitochondrial function to treat heart failure
After a heart attack, the heart struggles to recoup and maintain energy. One third of patients develop heart…
Transforming obese fat cells into energy burners
Ordinary fat cells in obese animals can be induced to burn energy stores, generating substantial heat, according to…
A direct role for a mitochondrial targeting sequence in signalling stress
Endo, T. & Wiedemann, N. Molecular machineries and pathways of mitochondrial protein transport. Nat. Rev. Mol. Cell Biol.…
Scientists Find a Way to Help Aging Cells “Swap Their Batteries”
For decades, aging at the cellular level has been blamed on one tiny structure inside our cells: the…
Microbe discovery reveals ancient clues to how complex life began
Most days you move through the world without thinking about the invisible creatures that surround you. Yet one…
Neuromedin B drives goat granulosa cell proliferation via NMBR-mediated calcium homeostasis | Journal of Ovarian Research
Goat ovaries and follicles collection Thirty-six healthy female goats with uniform genetic backgrounds and rearing conditions were enrolled…
Dysfunctional mitochondria shown to initiate the onset of Parkinson’s
For decades, scientists have known that mitochondria, which produce energy inside our cells, malfunction in Parkinson’s disease. But…
New gene-editing method can correct many disease-causing mutations in mammalian cells
Some genetic disorders-such as cystic fibrosis, hemophilia and Tay Sachs disease-involve many mutations in a person’s genome, often…
Scientists “Improve on Mother Nature” To Create Powerful Cancer-Killing Molecule
Researchers discovered that bacteria inside tumors can create a molecule that makes chemotherapy more powerful. This surprising microbial…
Ribonucleotide incorporation into mitochondrial DNA drives inflammation
Cell culture, transfection and RNA interference MEFs and HeLa cells were maintained in DMEM-GlutaMAX (Thermo Fisher Scientific) containing…
Rare ABCA7 gene variants linked to Alzheimer’s risk
A new study from MIT neuroscientists reveals how rare variants of a gene called ABCA7 may contribute to…