New gene-editing method can correct many disease-causing mutations in mammalian cells
Some genetic disorders-such as cystic fibrosis, hemophilia and Tay Sachs disease-involve many mutations in a person’s genome, often…
Scientists “Improve on Mother Nature” To Create Powerful Cancer-Killing Molecule
Researchers discovered that bacteria inside tumors can create a molecule that makes chemotherapy more powerful. This surprising microbial…
Ribonucleotide incorporation into mitochondrial DNA drives inflammation
Cell culture, transfection and RNA interference MEFs and HeLa cells were maintained in DMEM-GlutaMAX (Thermo Fisher Scientific) containing…
Rare ABCA7 gene variants linked to Alzheimer’s risk
A new study from MIT neuroscientists reveals how rare variants of a gene called ABCA7 may contribute to…
Preclinical Data Spotlights Gene with Therapeutic Potential for Barth Syndrome
Barth Syndrome is a rare X-linked genetic condition caused by a mutation in the Tafazzin gene, which is…
Why Do We Need Sleep? Oxford Scientists Trace the Answer to Mitochondria
Oxford scientists have found that sleep may be triggered by tiny energy leaks in brain cell mitochondria, suggesting…
Locally produced proteins help mitochondria function | MIT News
Our cells produce a variety of proteins, each with a specific role that, in many cases, means that…
Aging brains lose key proteins despite intact genetic blueprints
An international research team involving the Leibniz Institute on Aging – Fritz Lipmann Institute (FLI) in Jena, the…
New data confirms efficacy of mitochondrial donation in preventing disease
The UK’s pioneering licensed IVF technique to reduce the risk of mitochondrial diseases carried out in Newcastle has…