A direct role for a mitochondrial targeting sequence in signalling stress
Endo, T. & Wiedemann, N. Molecular machineries and pathways of mitochondrial protein transport. Nat. Rev. Mol. Cell Biol.…
Scientists Find a Way to Help Aging Cells “Swap Their Batteries”
For decades, aging at the cellular level has been blamed on one tiny structure inside our cells: the…
Microbe discovery reveals ancient clues to how complex life began
Most days you move through the world without thinking about the invisible creatures that surround you. Yet one…
Neuromedin B drives goat granulosa cell proliferation via NMBR-mediated calcium homeostasis | Journal of Ovarian Research
Goat ovaries and follicles collection Thirty-six healthy female goats with uniform genetic backgrounds and rearing conditions were enrolled…
Dysfunctional mitochondria shown to initiate the onset of Parkinson’s
For decades, scientists have known that mitochondria, which produce energy inside our cells, malfunction in Parkinson’s disease. But…
New gene-editing method can correct many disease-causing mutations in mammalian cells
Some genetic disorders-such as cystic fibrosis, hemophilia and Tay Sachs disease-involve many mutations in a person’s genome, often…
Scientists “Improve on Mother Nature” To Create Powerful Cancer-Killing Molecule
Researchers discovered that bacteria inside tumors can create a molecule that makes chemotherapy more powerful. This surprising microbial…
Ribonucleotide incorporation into mitochondrial DNA drives inflammation
Cell culture, transfection and RNA interference MEFs and HeLa cells were maintained in DMEM-GlutaMAX (Thermo Fisher Scientific) containing…
Rare ABCA7 gene variants linked to Alzheimer’s risk
A new study from MIT neuroscientists reveals how rare variants of a gene called ABCA7 may contribute to…
Preclinical Data Spotlights Gene with Therapeutic Potential for Barth Syndrome
Barth Syndrome is a rare X-linked genetic condition caused by a mutation in the Tafazzin gene, which is…
Why Do We Need Sleep? Oxford Scientists Trace the Answer to Mitochondria
Oxford scientists have found that sleep may be triggered by tiny energy leaks in brain cell mitochondria, suggesting…
Locally produced proteins help mitochondria function | MIT News
Our cells produce a variety of proteins, each with a specific role that, in many cases, means that…