New genetic mutations linked to malaria drug resistance discovered
Researchers searching for genetic clues to the growing problem of malaria drug resistance identified new mutations associated with…
Scientists uncover how muscle actin filaments grow and renew themselves
Biophysicists unraveled a mystery of how muscles form at the molecular level and how they maintain their function.…
Pleiotropic effects of cis-regulatory mutations
Wray, G. A. The evolutionary significance of cis-regulatory mutations. Nat. Rev. Genet. 8, 206–216 (2007). Article CAS PubMed …
Scientists uncover why genome guardian p53 protein is uniquely prone to collapse
The protein p53 is often called the guardian of the genome for its central role in preventing cancer.…
Dual-pathway protein degradation approach could improve cancer treatment
Targeted protein degradation has become one of the most promising strategies in modern drug discovery, enabling scientists to…
Base editing corrects genetic mutation responsible for severe form of inherited epilepsy
University of Virginia School of Medicine scientists have used a next-generation form of gene editing to fix the…
Chronic colitis reshapes colon stem cells in ways that can accelerate tumour growth
Even after inflammation resolves, colonic stem cells can retain a hidden molecular memory that increases the likelihood of…
Transposable elements cause majority of lethal mutations in fruit flies
Most lethal mutations in wild fruit flies are driven by newly transferred jumping genes, not small DNA errors,…
Study identifies link between gut bacteria and deterioration of the brain in ALS, dementia
A significant discovery by Case Western Reserve University researchers could change how doctors treat two of the most…
DNA analysis of colorectal polyps improves diagnosis and treatment
In about 5–10% of colorectal cancer patients, hereditary factors play a role, with higher percentages among younger patients.…
This ‘super flu’ could cause widespread serious illness, experts say – Northeastern Global News
This ‘super flu’ could cause widespread serious illness, experts say Northeastern Global NewsWhy Is This Year’s Flu Season So…
Dysfunctional mitochondria shown to initiate the onset of Parkinson’s
For decades, scientists have known that mitochondria, which produce energy inside our cells, malfunction in Parkinson’s disease. But…