Varying mutation rates in healthy organs explain cancer risk
A new study by scientists at City of Hope® and TGen, part of City of Hope, found surprisingly…
Zebrafish study reveals how albinism gene influences embryonic eye development
Tiny, striped zebrafish are helping scientists trace how a gene linked to albinism influences eye development, work that…
Study reveals how CaMKIIα proteins organize during memory formation
Researchers at the Nano Life Science Institute (WPI-NanoLSI) at Kanazawa University, Kyoto University, SOKENDAI, and the National Institute…
Scientists discover tiny protein region that shapes tooth enamel
Tooth enamel looks simple from the outside and consists of a hard, smooth surface built to withstand years…
New genetic mutations linked to malaria drug resistance discovered
Researchers searching for genetic clues to the growing problem of malaria drug resistance identified new mutations associated with…
Scientists uncover how muscle actin filaments grow and renew themselves
Biophysicists unraveled a mystery of how muscles form at the molecular level and how they maintain their function.…
Pleiotropic effects of cis-regulatory mutations
Wray, G. A. The evolutionary significance of cis-regulatory mutations. Nat. Rev. Genet. 8, 206–216 (2007). Article CAS PubMed …
Scientists uncover why genome guardian p53 protein is uniquely prone to collapse
The protein p53 is often called the guardian of the genome for its central role in preventing cancer.…
Dual-pathway protein degradation approach could improve cancer treatment
Targeted protein degradation has become one of the most promising strategies in modern drug discovery, enabling scientists to…
Base editing corrects genetic mutation responsible for severe form of inherited epilepsy
University of Virginia School of Medicine scientists have used a next-generation form of gene editing to fix the…
Chronic colitis reshapes colon stem cells in ways that can accelerate tumour growth
Even after inflammation resolves, colonic stem cells can retain a hidden molecular memory that increases the likelihood of…
Transposable elements cause majority of lethal mutations in fruit flies
Most lethal mutations in wild fruit flies are driven by newly transferred jumping genes, not small DNA errors,…