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Browsing Tag

Nerve

13 posts
HHealth
Immune cells communicate across a continuous, bidirectional circuit between the CNS and periphery. Immune cells from across the body engage CNS tissues and, in turn, are shaped by signals returning from the brain. (Left) Under peripheral equilibrium, immune effectors mobilized from visceral organs, secondary lymphoid organs, hematopoietic tissues, and the peripheral nervous system (PNS) - including CD4+ and CD8+ T cells, B cells, monocytes (top 3 cell types), NK cells, dendritic cells, mast cells, neutrophils, and innate lymphoid cells (bottom cluster of cells) - engage the CNS in a homeostatic dialogue that supports neural cell health, plasticity, and repair, sustaining a protective environment. (Right) Age-associated dysfunction across the same peripheral compartments reshapes this circuit: altered immune effectors enter the CNS and contribute to shifting the local environment toward a degenerative state in which microglia adopt disease-associated programs, astrocytes become reactive, and neurons accumulate pathology. This model underscores how the same circuitry can yield protective or pathogenic outcomes and that neurodegeneration is downstream of dysfunctional brain-immune crosstalk. Study: Neurodegeneration as a dysregulation of neuroimmune crosstalk
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Disrupted brain-immune signaling may help drive neurodegeneration

  • August 24, 2026
From gut-primed T cells to microglial signaling and persistent gene-regulatory states, researchers map an intricate immune network that…
SScience
New data confirms efficacy of mitochondrial donation in preventing disease
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Researchers develop DNA aptamer to detect Alzheimer’s biomarkers

  • March 10, 2026
With aging populations on the rise, the need for better tools to diagnose and monitor Alzheimer’s disease (AD),…
SScience
New study identifies genes that shape human brain features
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Neuron lattice structure may guard against neurodegeneration

  • February 12, 2026
Brain cells are constantly swallowing material from the fluid that surrounds them – signaling molecules, nutrients, even pieces of their own surfaces – in a process…
HHealth
New study identifies genes that shape human brain features
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Silencing a specific brain circuit can prevent and reverse chronic pain

  • January 28, 2026
A neural circuit hidden in an understudied region of the brain plays a critical role in turning temporary…
SScience
New computational method reconstructs how cells decide their fate
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Stimulating immune cells could offer new treatment for nerve injury pain

  • January 8, 2026
Researchers at The University of Texas MD Anderson Cancer Center have discovered that targeting a specific immune process…
SScience
New computational method reconstructs how cells decide their fate
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New computational method reconstructs how cells decide their fate

  • December 31, 2025
Researchers from Kyushu University have developed an innovative computational method, called ddHodge, that can reconstruct the complex dynamics…
HHealth
Ivabradine fails to prevent myocardial injury after noncardiac surgery in large clinical trial
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White matter alterations connect coronary artery disease to cognitive decline

  • November 26, 2025
Individuals with coronary artery disease (CAD) – a constricting or blocking of blood vessels feeding the heart –…
HHealth
Harnessing nanotechnology to deliver CBD to the brain for neuropathic pain relief
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Harnessing nanotechnology to deliver CBD to the brain for neuropathic pain relief

  • November 8, 2025
Reaching for CBD-infused lotion or oil may seem like a low-risk way to find pain relief, but little…
HHealth
Researchers receive new funding to advance promising therapy for multiple sclerosis
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Researchers receive new funding to advance promising therapy for multiple sclerosis

  • September 16, 2025
A Canadian-led international research team, spearheaded by Dr. Fang Liu at the Centre for Addiction and Mental Health…
HHealth
Senior woman by the window smelling yellow daffodil,
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Smell loss emerges as the early behavioural sign of Alzheimer’s

  • September 4, 2025
New research reveals that immune cells attack brainstem nerve fibers linked to smell, making loss of smell the…
SScience
Groundbreaking approach combines 3D printing and stem cell biology for spinal cord injury recovery
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Groundbreaking approach combines 3D printing and stem cell biology for spinal cord injury recovery

  • August 25, 2025
For the first time, a research team at the University of Minnesota Twin Cities demonstrated a groundbreaking process…
NNutrition
Understanding the importance of B vitamins for health
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New research unveils vast influence of B vitamins on health and disease

  • August 6, 2025
Eight essential nutrients make up the suite of B vitamins also known as the B complex. Researchers from…
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