Disrupted brain-immune signaling may help drive neurodegeneration
From gut-primed T cells to microglial signaling and persistent gene-regulatory states, researchers map an intricate immune network that…
Semaglutide Falls Short in Alzheimer’s Phase 3 Trials
Phase 3 trials show oral semaglutide failed to slow early Alzheimer’s progression, potentially limiting its expansion beyond metabolic…
New Tool Maps Hyperarousal Dimensions for Personalized Care
Researchers identified seven dimensions of hyperarousal and developed the Transdiagnostic Hyperarousal Dimensions Questionnaire (THDQ), a tool designed to…
Researchers develop DNA aptamer to detect Alzheimer’s biomarkers
With aging populations on the rise, the need for better tools to diagnose and monitor Alzheimer’s disease (AD),…
Exercise alleviates cognitive dysfunction in Alzheimer’s disease mice via skeletal muscle-derived extracellular vesicles that enhance plaque clearance by microglia
Knopman, D. S. et al. Alzheimer disease. Nat. Rev. Dis. Primers 7, 33 (2021). Article PubMed PubMed Central …
Scientists uncover nanoplastics in brain tissue and question their role in neurological disease
Scientists are detecting nanoplastics in human brain tissue and exploring how these particles may influence the risk of…
Alzheimer’s plaques decline after CAR-T immune cell treatment in preclinical study
A novel CAR-T cell approach targets amyloid plaques in preclinical Alzheimer models, raising the possibility that engineered immune…
New spatial omics platform advances biomedical research in Spain
Spatial omics is a new generation of technologies that allow scientists to study cells in their original location…
Alzheimer’s hits women harder: Can omega-3 turn the tide?
There’s something quietly unfair about Alzheimer’s and women. Studies consistently show that women are more likely to develop…
Restoring protein production in motor neuron axons
Researchers at VIB and KU Leuven have identified a molecular process that allows motor neurons to maintain protein…
Genetic variation in the glucagon-like peptide-1 receptor protein encoding region is associated with higher heart rate variability, but not with neurodegeneration of the brain, retina, and peripheral nerves: The Maastricht study | Cardiovascular Diabetology
Badrov MB, Mak S, Floras JS. Cardiovascular autonomic disturbances in heart failure with preserved ejection fraction. Can J…
Advanced imaging exposes breakdown in brain cell communication linked to Alzheimer’s
Research led by The Ohio State University Wexner Medical Center and College of Medicine explores the ways brain…