Oral semaglutide fails to slow early Alzheimer’s decline in two phase 3 trials
Despite hopes raised by earlier observational studies and biomarker shifts, The Lancet trials found that oral semaglutide did…
New research initiative aims to predict and prevent diseases before they start
What if doctors could tell you a disease was coming years before you felt a single symptom-and stop…
Transforming obese fat cells into energy burners
Ordinary fat cells in obese animals can be induced to burn energy stores, generating substantial heat, according to…
Study identifies PPP2R5C blood marker that may detect Alzheimer’s disease earlier
Researchers report that declining PPP2R5C levels in blood may signal early Alzheimer’s pathology, offering new insight into tau…
Alzheimer’s plaques decline after CAR-T immune cell treatment in preclinical study
A novel CAR-T cell approach targets amyloid plaques in preclinical Alzheimer models, raising the possibility that engineered immune…
Hippocampus reorganizes memories to anticipate future outcomes, study finds
A preclinical study published in Nature has found evidence that the hippocampus, the brain region that stores memory, also reorganizes…
Study reveals a therapeutic vulnerability in aggressive subtype of triple-negative breast cancer
Dec 26 2025 A new study published today in Science Translational Medicine by researchers at The University of…
Small increases in daily steps may slow Alzheimer’s progression
Increasing your steps by even a little bit may help slow down the progression of Alzheimer’s disease among…
Building muscle shown to protect against obesity-related organ damage
People with excess body fat who build and keep muscle may be less likely to develop obesity-induced heart,…
Genetic modification enhances “living drugs” for blood cancers
CAR T cells are patient-derived, genetically engineered immune cells. They are “living drugs” and constitute a milestone in…
Genetic study shows dual GIPR/GLP1R action curbs binge alcohol use
New genetic evidence suggests that targeting GIPR and GLP1R could reduce harmful drinking patterns while improving liver and…
Depressive symptoms may interfere with learning to actively avoid unpleasant events
Depression alters how people pursue rewards, but, conversely, whether depressive symptoms influence how people learn to avoid nonrewarding,…