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Browsing Tag

Preclinical

18 posts
HHealth
Study: Hormone replacement therapy and dementia risk among postmenopausal women: Identifying responsive subgroups in the UK Biobank. Image Credit: Andrey_Popov / Shutterstock
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HRT linked to lower dementia risk, but timing and menopause type matter

  • August 28, 2026
A large UK Biobank analysis reveals how menopause type, estrogen exposure, genetics, and the timing of HRT may…
HHealth
From caffeine to trigonelline, coffee has surprising links to muscle biology
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From caffeine to trigonelline, coffee has surprising links to muscle biology

  • August 25, 2026
From NAD+ metabolism and glucose uptake to muscle mass and frailty, researchers mapped how coffee and its compounds…
HHealth
First-in-class experimental CAR T-cell therapy shows promise against solid tumors
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First-in-class experimental CAR T-cell therapy shows promise against solid tumors

  • July 3, 2026
Researchers with the Charbonneau Cancer Institute at the University of Calgary and McMaster University have identified a unique…
SScience
Human telomerase shows limited function across different animal species
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Human telomerase shows limited function across different animal species

  • May 6, 2026
A new research paper was published in Volume 18 of Aging-US on April 13, 2026, titled “Cross species activity of TERT…
HHealth
Study: Efficacy and safety of oral semaglutide 14 mg (flexible dose) in early-stage symptomatic Alzheimer
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Oral semaglutide fails to slow early Alzheimer’s decline in two phase 3 trials

  • March 23, 2026
Despite hopes raised by earlier observational studies and biomarker shifts, The Lancet trials found that oral semaglutide did…
HHealth
Time-restricted feeding reduces disease activity and inflammation in Crohn's patients
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New research initiative aims to predict and prevent diseases before they start

  • March 2, 2026
What if doctors could tell you a disease was coming years before you felt a single symptom-and stop…
HHealth
Research offers hope for weight loss without gastrointestinal distress
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Transforming obese fat cells into energy burners

  • February 24, 2026
Ordinary fat cells in obese animals can be induced to burn energy stores, generating substantial heat, according to…
HHealth
Study: Neuronal PPP2R5C in plasma is a potential biomarker for early diagnosis of Alzheimer’s disease
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Study identifies PPP2R5C blood marker that may detect Alzheimer’s disease earlier

  • February 23, 2026
Researchers report that declining PPP2R5C levels in blood may signal early Alzheimer’s pathology, offering new insight into tau…
HHealth
Study: Engineering chimeric antigen receptor CD4 T cells for Alzheimer’s disease. Image Credit: Andrii Vodolazhskyi / Shutterstock
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Alzheimer’s plaques decline after CAR-T immune cell treatment in preclinical study

  • February 12, 2026
A novel CAR-T cell approach targets amyloid plaques in preclinical Alzheimer models, raising the possibility that engineered immune…
SScience
Uncovering the secrets of ‘SuperAgers’ and cognitive longevity
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Hippocampus reorganizes memories to anticipate future outcomes, study finds

  • January 30, 2026
A preclinical study published in Nature has found evidence that the hippocampus, the brain region that stores memory, also reorganizes…
HHealth
Genetic risk score can help identify women at higher risk of invasive breast cancer
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Study reveals a therapeutic vulnerability in aggressive subtype of triple-negative breast cancer

  • December 27, 2025
Dec 26 2025 A new study published today in Science Translational Medicine by researchers at The University of…
HHealth
Intensive sports in adolescents trigger complex heart adaptations
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Small increases in daily steps may slow Alzheimer’s progression

  • November 4, 2025
Increasing your steps by even a little bit may help slow down the progression of Alzheimer’s disease among…
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