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Browsing Tag

Preclinical

20 posts
HHealth
New drug forces aggressive leukemia cells to die from stress
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New drug forces aggressive leukemia cells to die from stress

  • September 8, 2026
Pushing the accelerator and the brake at the same time is rarely a good idea. But researchers at…
HHealth
Inhibitory neurons act as a brake on brain tumor growth
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Inhibitory neurons act as a brake on brain tumor growth

  • September 7, 2026
Brain tumors do not grow in isolation. They develop within the highly active environment of the brain, where…
HHealth
Study: Hormone replacement therapy and dementia risk among postmenopausal women: Identifying responsive subgroups in the UK Biobank. Image Credit: Andrey_Popov / Shutterstock
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HRT linked to lower dementia risk, but timing and menopause type matter

  • August 28, 2026
A large UK Biobank analysis reveals how menopause type, estrogen exposure, genetics, and the timing of HRT may…
HHealth
From caffeine to trigonelline, coffee has surprising links to muscle biology
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From caffeine to trigonelline, coffee has surprising links to muscle biology

  • August 25, 2026
From NAD+ metabolism and glucose uptake to muscle mass and frailty, researchers mapped how coffee and its compounds…
HHealth
First-in-class experimental CAR T-cell therapy shows promise against solid tumors
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First-in-class experimental CAR T-cell therapy shows promise against solid tumors

  • July 3, 2026
Researchers with the Charbonneau Cancer Institute at the University of Calgary and McMaster University have identified a unique…
SScience
Human telomerase shows limited function across different animal species
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Human telomerase shows limited function across different animal species

  • May 6, 2026
A new research paper was published in Volume 18 of Aging-US on April 13, 2026, titled “Cross species activity of TERT…
HHealth
Study: Efficacy and safety of oral semaglutide 14 mg (flexible dose) in early-stage symptomatic Alzheimer
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Oral semaglutide fails to slow early Alzheimer’s decline in two phase 3 trials

  • March 23, 2026
Despite hopes raised by earlier observational studies and biomarker shifts, The Lancet trials found that oral semaglutide did…
HHealth
Time-restricted feeding reduces disease activity and inflammation in Crohn's patients
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New research initiative aims to predict and prevent diseases before they start

  • March 2, 2026
What if doctors could tell you a disease was coming years before you felt a single symptom-and stop…
HHealth
Research offers hope for weight loss without gastrointestinal distress
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Transforming obese fat cells into energy burners

  • February 24, 2026
Ordinary fat cells in obese animals can be induced to burn energy stores, generating substantial heat, according to…
HHealth
Study: Neuronal PPP2R5C in plasma is a potential biomarker for early diagnosis of Alzheimer’s disease
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Study identifies PPP2R5C blood marker that may detect Alzheimer’s disease earlier

  • February 23, 2026
Researchers report that declining PPP2R5C levels in blood may signal early Alzheimer’s pathology, offering new insight into tau…
HHealth
Study: Engineering chimeric antigen receptor CD4 T cells for Alzheimer’s disease. Image Credit: Andrii Vodolazhskyi / Shutterstock
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Alzheimer’s plaques decline after CAR-T immune cell treatment in preclinical study

  • February 12, 2026
A novel CAR-T cell approach targets amyloid plaques in preclinical Alzheimer models, raising the possibility that engineered immune…
SScience
Uncovering the secrets of ‘SuperAgers’ and cognitive longevity
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Hippocampus reorganizes memories to anticipate future outcomes, study finds

  • January 30, 2026
A preclinical study published in Nature has found evidence that the hippocampus, the brain region that stores memory, also reorganizes…
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