Targeting cyclin-dependent kinases offers new pathways for cancer therapy
Cancer is the second leading cause of death in Germany. In the search for new therapeutic approaches that…
New AI-based program is a shrink ray for proteins
A new AI-based program, dubbed Raygun, can suggest strategic cuts to a protein’s amino acid sequence to…
Chemists use programmable DNA to build precise protein crystals
For decades, scientists have largely relied on painstaking trial and error to coax proteins into crystalline forms. Crystallization…
Scientists visualize a key cell protein regulating inflammatory disease pathways
University of Cincinnati structural biologists are the first in the world to visualize a key cell protein as part…
Scientists identify a molecular switch that controls water flow in the gut
Although constipation and diarrhea may seem like opposite problems, they both hinge on the same underlying issue: how…
New fluorescence method lights up a better glycan-cleaving enzyme
Attached to many proteins are glycans—complex strings of sugars—that change how the whole unit functions. Removing them…