{"id":137876,"date":"2025-09-12T05:40:12","date_gmt":"2025-09-12T05:40:12","guid":{"rendered":"https:\/\/www.newsbeep.com\/ca\/137876\/"},"modified":"2025-09-12T05:40:12","modified_gmt":"2025-09-12T05:40:12","slug":"mounjaro-golden-dose-could-be-dangerous-and-lead-to-overdose-pharmacist-warns","status":"publish","type":"post","link":"https:\/\/www.newsbeep.com\/ca\/137876\/","title":{"rendered":"Mounjaro &#8216;golden dose&#8217; could be &#8216;dangerous&#8217; and lead to overdose, pharmacist warns"},"content":{"rendered":"<p>Pharmaceutical companies are warning against tampering with pens and experts have outlined the major risks.<img decoding=\"async\" src=\"https:\/\/www.newsbeep.com\/ca\/wp-content\/uploads\/2025\/09\/0_man-holding-kwikpen.jpg\" alt=\"A man injects himself with a Mounjaro pen while standing topless\" loading=\"eager\"  \/>While the KwikPen is not reducing in size, the volume of the medicine inside will be reduced in the future(Image:  Peter Dazeley via Getty Images)<\/p>\n<p class=\"Paragraph_paragraph-text__PVKlh \" data-tmdatatrack=\"content-unit\" data-tmdatatrack-type=\"paragraph\">Mounjaro, the brand name for tirzepatide, is a drug that lowers blood sugar levels but has rose to prominence in the last year for its use as an injectable <a class=\"TextLink_text-link__dBSS0 TextLink_enabled__dJF3l\" href=\"https:\/\/www.dailyrecord.co.uk\/lifestyle\/what-mounjaro-everything-know-nhs-34476325\" target=\"_blank\" aria-label=\"weight loss medicationLink opens in a new tab.\" tabindex=\"0\" rel=\"nofollow noopener\">weight loss medication<\/a> that has seen overweight Brits lose tens of pounds.<\/p>\n<p class=\"Paragraph_paragraph-text__PVKlh \" data-tmdatatrack=\"content-unit\" data-tmdatatrack-type=\"paragraph\">This week, <a class=\"TextLink_text-link__dBSS0 TextLink_enabled__dJF3l\" href=\"https:\/\/www.dailyrecord.co.uk\/lifestyle\/mounjaro-reducing-size-following-price-35874955\" target=\"_blank\" aria-label=\"the Record reported that Mounjaro manufacturer Eli Lilly Link opens in a new tab.\" tabindex=\"0\" rel=\"nofollow noopener\">the Record reported that Mounjaro manufacturer Eli Lilly <\/a>is reducing the amount in its injection pens, removing the so-called &#8216;golden dose&#8217;. This means users who have been able to squeeze an extra dose from the leftover medicine in each syringe will no longer be able to get five weeks out of their monthly prescription.<\/p>\n<p class=\"Paragraph_paragraph-text__PVKlh \" data-tmdatatrack=\"content-unit\" data-tmdatatrack-type=\"paragraph\">The Mounjaro pen currently has an excess of medication to ensure proper priming of the needle before administration and to make sure there is enough for the four doses following this each time.<\/p>\n<p class=\"Paragraph_paragraph-text__PVKlh \" data-tmdatatrack=\"content-unit\" data-tmdatatrack-type=\"paragraph\">Instead of discarding this, people on social media have been encouraging individuals to try out the &#8220;fifth dose&#8221; to get more for their money. However, pharmacists have warned that taking this dose can be &#8220;dangerous&#8221;.<\/p>\n<p class=\"Paragraph_paragraph-text__PVKlh \" data-tmdatatrack=\"content-unit\" data-tmdatatrack-type=\"paragraph\">To keep you clued up, the experts at <a class=\"TextLink_text-link__dBSS0 TextLink_enabled__dJF3l\" href=\"https:\/\/www.chemist-4-u.com\/mounjaro\" target=\"_blank\" aria-label=\"Chemist4U Link opens in a new tab.\" tabindex=\"0\" rel=\"nofollow noopener\">Chemist4U <\/a>sharing the risks of taking the \u201cgolden dose\u201d in Mounjaro pens.<\/p>\n<p>What are risks of taking the &#8216;golden dose&#8217;?<img decoding=\"async\" src=\"https:\/\/www.newsbeep.com\/ca\/wp-content\/uploads\/2025\/09\/0_mounjaro-pen.jpg\" alt=\"A photo illustration of a Mounjaro pen \" loading=\"lazy\"  \/>Mounjaro has been recommended to help dangerously obese people lose weight on the NHS(Image: Peter Dazeley via Getty Images)Overdosing and pancreatic issues<\/p>\n<p class=\"Paragraph_paragraph-text__PVKlh \" data-tmdatatrack=\"content-unit\" data-tmdatatrack-type=\"paragraph\">The &#8220;5th dose&#8221; or &#8220;golden dose&#8221; refers to a self-added dose to the pen&#8217;s standard four doses. It&#8217;s believed that this extra amount of liquid is added to ensure there is sufficient excess fluid to prime the pen.<\/p>\n<p class=\"Paragraph_paragraph-text__PVKlh \" data-tmdatatrack=\"content-unit\" data-tmdatatrack-type=\"paragraph\">The extra liquid is not a measured or intended dose, and its volume may be inconsistent, which can lead to under dosing or overdosing and even the risk of injecting expired <a class=\"TextLink_text-link__dBSS0 TextLink_enabled__dJF3l\" href=\"https:\/\/www.dailyrecord.co.uk\/lifestyle\/nhs-warning-over-common-medications-35309685\" target=\"_blank\" aria-label=\"medicationLink opens in a new tab.\" tabindex=\"0\" rel=\"nofollow noopener\">medication<\/a>.<\/p>\n<p><img decoding=\"async\" src=\"https:\/\/www.newsbeep.com\/ca\/wp-content\/uploads\/2025\/09\/1757655611_318_0_WACOMMUNITYQR3.jpg\" alt=\"\"  \/>Join the Daily Record WhatsApp community!<\/p>\n<p class=\"Paragraph_paragraph-text__PVKlh \" data-tmdatatrack=\"content-unit\" data-tmdatatrack-type=\"paragraph\">Get the latest news sent straight to your messages by joining our WhatsApp community today.<\/p>\n<p class=\"Paragraph_paragraph-text__PVKlh \" data-tmdatatrack=\"content-unit\" data-tmdatatrack-type=\"paragraph\">You&#8217;ll receive daily updates on breaking news as well as the top headlines across Scotland.<\/p>\n<p class=\"Paragraph_paragraph-text__PVKlh \" data-tmdatatrack=\"content-unit\" data-tmdatatrack-type=\"paragraph\">No one will be able to see who is signed up and no one can send messages except the Daily Record team.<\/p>\n<p class=\"Paragraph_paragraph-text__PVKlh \" data-tmdatatrack=\"content-unit\" data-tmdatatrack-type=\"paragraph\">All you have to do is <a class=\"TextLink_text-link__dBSS0 TextLink_enabled__dJF3l\" href=\"https:\/\/chat.whatsapp.com\/BZamc48XMaoEqKkIN7GWxV\" target=\"_self\" aria-label=\"\" tabindex=\"0\" rel=\"nofollow noopener\">click here if you&#8217;re on mobile<\/a>, select &#8216;Join Community&#8217; and you&#8217;re in!<\/p>\n<p class=\"Paragraph_paragraph-text__PVKlh \" data-tmdatatrack=\"content-unit\" data-tmdatatrack-type=\"paragraph\">If you&#8217;re on a desktop, simply scan the QR code above with your phone and click &#8216;Join Community&#8217;.<\/p>\n<p class=\"Paragraph_paragraph-text__PVKlh \" data-tmdatatrack=\"content-unit\" data-tmdatatrack-type=\"paragraph\">We also treat our community members to special offers, promotions, and adverts from us and our partners. If you don\u2019t like our community, you can check out any time you like.<\/p>\n<p class=\"Paragraph_paragraph-text__PVKlh \" data-tmdatatrack=\"content-unit\" data-tmdatatrack-type=\"paragraph\">To leave our community click on the name at the top of your screen and choose &#8216;exit group&#8217;.<\/p>\n<p class=\"Paragraph_paragraph-text__PVKlh \" data-tmdatatrack=\"content-unit\" data-tmdatatrack-type=\"paragraph\">If you\u2019re curious, you can read our <a class=\"TextLink_text-link__dBSS0 TextLink_enabled__dJF3l\" href=\"https:\/\/www.dailyrecord.co.uk\/privacy-notice\/\" target=\"_self\" aria-label=\"\" tabindex=\"0\" rel=\"nofollow noopener\">Privacy Notice.<\/a><\/p>\n<p class=\"Paragraph_paragraph-text__PVKlh \" data-tmdatatrack=\"content-unit\" data-tmdatatrack-type=\"paragraph\">Trying to extract a fifth dose can also damage the pen, <a class=\"TextLink_text-link__dBSS0 TextLink_enabled__dJF3l\" href=\"https:\/\/www.dailyrecord.co.uk\/news\/health\/everything-you-need-know-mounjaro-35438034\" target=\"_blank\" aria-label=\"increase the risk of side effectsLink opens in a new tab.\" tabindex=\"0\" rel=\"nofollow noopener\">increase the risk of side effects<\/a>, and disrupt your treatment plan. Always use your pen exactly as prescribed and discard the pen after four doses, even if some liquid remains.<\/p>\n<p class=\"Paragraph_paragraph-text__PVKlh \" data-tmdatatrack=\"content-unit\" data-tmdatatrack-type=\"paragraph\">&#8220;The higher the dose, the higher the risk of gastrointestinal reactions such as <a class=\"TextLink_text-link__dBSS0 TextLink_enabled__dJF3l\" href=\"https:\/\/www.dailyrecord.co.uk\/lifestyle\/doctors-five-tips-managing-nausea-35157887\" target=\"_blank\" aria-label=\"nauseaLink opens in a new tab.\" tabindex=\"0\" rel=\"nofollow noopener\">nausea<\/a>, vomiting, or diarrhoea as well as the potential for an increased risk of pancreatic issues,&#8221; said Ayesha Bashir, Prescribing Pharmacist at Chemist4U.<\/p>\n<p>Sterility and performance<\/p>\n<p class=\"Paragraph_paragraph-text__PVKlh \" data-tmdatatrack=\"content-unit\" data-tmdatatrack-type=\"paragraph\">The Kwikpen used to administer Mounjaro must be discarded after the four doses, or after a period of 30 days after the first dose is used, as per manufacturer instructions.<\/p>\n<p class=\"Paragraph_paragraph-text__PVKlh \" data-tmdatatrack=\"content-unit\" data-tmdatatrack-type=\"paragraph\">Continuing use beyond that may present unknown sterility and performance risks , including potential health issues.<\/p>\n<p class=\"Paragraph_paragraph-text__PVKlh \" data-tmdatatrack=\"content-unit\" data-tmdatatrack-type=\"paragraph\">If a user suffers side effects, dosing failure, or infection after using a pen beyond its approved use period, Eli Lilly may decline responsibility, which could also undermine the legitimacy of any reported adverse event or claim.<\/p>\n<p>Risk of bacterial contamination and infection<img decoding=\"async\" src=\"https:\/\/www.newsbeep.com\/ca\/wp-content\/uploads\/2025\/09\/0_woman-injecting-kwikpen.jpg\" alt=\"A woman injects herself with a Mounjaro pen\" loading=\"lazy\"  \/>A small amount of medication remains in the pen after the final injection (Image: Peter Dazeley 2025)<\/p>\n<p class=\"Paragraph_paragraph-text__PVKlh \" data-tmdatatrack=\"content-unit\" data-tmdatatrack-type=\"paragraph\">Opening the Mounjaro KwikPen and extracting medication with a syringe can compromise the pen\u2019s sterile interior and introduce the risk of bacterial contamination or infection.<\/p>\n<p class=\"Paragraph_paragraph-text__PVKlh \" data-tmdatatrack=\"content-unit\" data-tmdatatrack-type=\"paragraph\">A recent lab study of insulin vials from diabetic patients found that 6.2 per cent of vials were contaminated with bacteria due to syringe reuse and poor storage conditions.<\/p>\n<p class=\"Paragraph_paragraph-text__PVKlh \" data-tmdatatrack=\"content-unit\" data-tmdatatrack-type=\"paragraph\">This shows how even non-clinical, household-level handling can introduce pathogens when sterile needles are tampered with or reused inappropriately.<\/p>\n<p>Misusing or &#8216;stretching&#8217; pens can spark side effects<\/p>\n<p class=\"Paragraph_paragraph-text__PVKlh \" data-tmdatatrack=\"content-unit\" data-tmdatatrack-type=\"paragraph\">Jason Murphy, Head of Pharmacy and <a class=\"TextLink_text-link__dBSS0 TextLink_enabled__dJF3l\" href=\"https:\/\/www.chemist-4-u.com\/weight-loss\/weight-loss-injections\" target=\"_blank\" aria-label=\"weight loss injectionsLink opens in a new tab.\" tabindex=\"0\" rel=\"nofollow noopener\">weight loss injections<\/a> expert at <a class=\"TextLink_text-link__dBSS0 TextLink_enabled__dJF3l\" href=\"https:\/\/www.chemist-4-u.com\/mounjaro\" target=\"_blank\" aria-label=\"Chemist4ULink opens in a new tab.\" tabindex=\"0\" rel=\"nofollow noopener\">Chemist4U<\/a>, said: &#8220;People will experience more periods of hunger, resulting in overeating and hampered results.<\/p>\n<p class=\"Paragraph_paragraph-text__PVKlh \" data-tmdatatrack=\"content-unit\" data-tmdatatrack-type=\"paragraph\">&#8220;Also, when they next inject, their body will have to get used to a higher dose again, leading to potential side effects such as prolonged nausea. \u201d<\/p>\n<p class=\"Paragraph_paragraph-text__PVKlh \" data-tmdatatrack=\"content-unit\" data-tmdatatrack-type=\"paragraph\">Jason said professionals and regulators are aware of the growing trend of Mounjaro KwikPen misuse and Medicines and Healthcare products Regulatory Agency (MHR) are monitoring it.<\/p>\n","protected":false},"excerpt":{"rendered":"Pharmaceutical companies are warning against tampering with pens and experts have outlined the major risks.While the KwikPen is&hellip;\n","protected":false},"author":2,"featured_media":137877,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[33],"tags":[49,48,2971,84,890,377,1229,1942],"class_list":{"0":"post-137876","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-medication","8":"tag-ca","9":"tag-canada","10":"tag-drugs","11":"tag-health","12":"tag-lifestyle","13":"tag-medication","14":"tag-obesity","15":"tag-social-media"},"_links":{"self":[{"href":"https:\/\/www.newsbeep.com\/ca\/wp-json\/wp\/v2\/posts\/137876","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.newsbeep.com\/ca\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.newsbeep.com\/ca\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/ca\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/ca\/wp-json\/wp\/v2\/comments?post=137876"}],"version-history":[{"count":0,"href":"https:\/\/www.newsbeep.com\/ca\/wp-json\/wp\/v2\/posts\/137876\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/ca\/wp-json\/wp\/v2\/media\/137877"}],"wp:attachment":[{"href":"https:\/\/www.newsbeep.com\/ca\/wp-json\/wp\/v2\/media?parent=137876"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.newsbeep.com\/ca\/wp-json\/wp\/v2\/categories?post=137876"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.newsbeep.com\/ca\/wp-json\/wp\/v2\/tags?post=137876"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}