Find the first installment of the interview here<\/a>.<\/p>\n Enterobacterales bacterium<\/p>\n
Your browser does not support the audio element.<\/p>\n
Listen to ICT’s interview with Danielle Rankin, PhD, MPH, CIC, the lead author of the CDC study.<\/p>\n
In the second part of our conversation with Danielle Rankin, PhD, MPH, CIC, epidemiologist with the CDC, she expanded on the infection prevention strategies and surveillance needs surrounding the rise of New Delhi metallo-\u03b2-lactamase carbapenem-resistant Enterobacterales (NDM-CRE). She is the lead author of a recent study published in the Annals of Internal Medicine.<\/p>\n
Rankin emphasized that early infection control measures are critical when a case is detected. \u201cIt\u2019s really important that IPs work with their state and local health care-associated infections and antimicrobial resistance programs to prevent spread,\u201d she said. Patients hospitalized with NDM-CRE should be placed on contact precautions, while long-term care residents require enhanced barrier precautions. She also underscored the basics: \u201cReinforce the importance of hand hygiene\u2026before touching a patient, before performing an aseptic task, after contact with bodily fluids, and, of course, after glove removal.\u201d<\/p>\n
Environmental hygiene remains equally vital. High-touch surfaces, such as bed rails, call buttons, and light switches, should be disinfected regularly. Additionally, shared equipment like portable X-ray machines must be cleaned thoroughly between patients. \u201cYou also want to make sure that staff are not pouring patient waste down sink drains,\u201d Rankin cautioned, citing sinks as a known environmental reservoir.<\/p>\n
Hand hygiene options prompted a practical discussion. \u201cHand sanitizer should be used and can be used in all instances except if a provider\u2019s hands are contaminated from blood or bodily fluids\u2014then they need to actually perform hand washing,\u201d Rankin explained.<\/p>\n
Beyond daily practices, Rankin highlighted the importance of timely surveillance and mechanism-specific testing. \u201cThe primary need is to really obtain prompt mechanism testing for CRE so this information can be used for treatment selection,\u201d she said. Yet she acknowledged barriers, including the lack of guaranteed reimbursement for clinical laboratories. Expanding testing capacity while maintaining strong public health laboratory support is essential for rapid response.<\/p>\n
Her message for infection preventionists and epidemiologists was clear: \u201cHistorically, the most common carbapenemase was KPC [Klebsiella pneumoniae carbapenemase], but now we\u2019re seeing this surge of NDM-CRE in the United States, which really threatens to reverse years of stable or declining CRE rates.\u201d With only 2 approved beta-lactam drugs effective against NDM-CRE, Rankin urged facilities to integrate mechanism testing into their workflows and use the CDC\u2019s AR Lab Network when local resources are unavailable.<\/p>\n
\u201cInfection control interventions must be timely,\u201d Rankin concluded, \u201cto ensure patients receive appropriate therapy and facilities can prevent further spread.\u201d<\/p>\n
Read Rankin and her colleagues\u2019 study published in the Annals of Internal Medicine here<\/a>.<\/p>\n Find the first installment of the interview here<\/a>.<\/p>\n Enterobacterales bacterium<\/p>\n
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