{"id":212542,"date":"2025-10-14T14:51:09","date_gmt":"2025-10-14T14:51:09","guid":{"rendered":"https:\/\/www.newsbeep.com\/ca\/212542\/"},"modified":"2025-10-14T14:51:09","modified_gmt":"2025-10-14T14:51:09","slug":"no-clinical-differences-between-outside-in-and-all-inside-techniques-in-medial-meniscus-repair-emphasizing-minimal-clinically-important-difference-mcid-based-outcomes-bmc-musculoskeletal-disorde","status":"publish","type":"post","link":"https:\/\/www.newsbeep.com\/ca\/212542\/","title":{"rendered":"No clinical differences between outside-in and all-inside techniques in medial meniscus repair: emphasizing Minimal Clinically Important Difference (MCID) -based outcomes | BMC Musculoskeletal Disorders"},"content":{"rendered":"<p>Patient selection and groups<\/p>\n<p>This retrospective study was conducted following approval from the local ethics committee. A total of 93 patients with isolated medial meniscus tears, with tear types recorded, and treated using either the outside-in (OI) or all-inside (AI) technique, were included in the study. Patients were recruited from two different orthopedic clinics.<\/p>\n<p>Inclusion criteria consisted of: Age\u2009\u2265\u200918 years, Isolated medial meniscus tear located in anatomical zone-3 or zone-4 [<a data-track=\"click\" data-track-action=\"reference anchor\" data-track-label=\"link\" data-test=\"citation-ref\" aria-label=\"Reference 6\" title=\"Cinque ME, DePhillipo NN, Moatshe G, et al. Clinical outcomes of inside-out meniscal repair according to anatomic zone of the meniscal tear. Orthop J Sports Med. 2019. &#010;                  https:\/\/doi.org\/10.1177\/2325967119860806&#010;                  &#010;                .\" href=\"http:\/\/bmcmusculoskeletdisord.biomedcentral.com\/articles\/10.1186\/s12891-025-09145-2#ref-CR6\" id=\"ref-link-section-d23746538e587\" rel=\"nofollow noopener\" target=\"_blank\">6<\/a>, <a data-track=\"click\" data-track-action=\"reference anchor\" data-track-label=\"link\" data-test=\"citation-ref\" aria-label=\"Reference 8\" title=\"D\u2019Ambrosi R, Kambhampati SBS. Upsurge in publications on ramp lesions of the meniscus: a bibliometric study. Knee Surg Relat Res. 2023;35(1):14.\" href=\"http:\/\/bmcmusculoskeletdisord.biomedcentral.com\/articles\/10.1186\/s12891-025-09145-2#ref-CR8\" id=\"ref-link-section-d23746538e590\" rel=\"nofollow noopener\" target=\"_blank\">8<\/a>, <a data-track=\"click\" data-track-action=\"reference anchor\" data-track-label=\"link\" data-test=\"citation-ref\" aria-label=\"Reference 22\" title=\"\u015amigielski R, Becker R, Zdanowicz U, Ciszek B. Medial meniscus anatomy\u2014from basic science to treatment. Knee Surg Sports Traumatol Arthrosc. 2015;23(1):8\u201314.\" href=\"http:\/\/bmcmusculoskeletdisord.biomedcentral.com\/articles\/10.1186\/s12891-025-09145-2#ref-CR22\" id=\"ref-link-section-d23746538e593\" rel=\"nofollow noopener\" target=\"_blank\">22<\/a>], A history of knee pain lasting no longer than three months, Positive meniscus tear signs on physical examination (McMurray test, joint line tenderness, or Apley test), Magnetic resonance imaging (MRI) confirmation of a medial meniscus tear, and surgical repair using either the OI or AI technique.<\/p>\n<p>Exclusion criteria included patients who had previously undergone a surgical procedure on the affected knee, as well as those with a concurrent lateral meniscus tear, medial meniscus posterior root tear, or varus malalignment, which is defined as hip-knee angle\u2009&lt;\u2009175. Additionally, patients with grade 3 or 4 cartilage damage, multiple ligament injuries, anterior cruciate ligament (ACL) or posterior cruciate ligament (PCL) injuries, and those younger than 18 years or older than 65 years were excluded from the study. All meniscal repairs were performed by two experienced orthopedic surgeons, each exclusively using one technique\u2014outside-in (first author) or all-inside (third author)\u2014both with over five years of experience in arthroscopic knee surgery, between 2020 and 2023, with a minimum follow-up of six months. Patients were divided into two groups (OI and AI) based on the technique used for meniscus repair (Fig. <a data-track=\"click\" data-track-label=\"link\" data-track-action=\"figure anchor\" href=\"http:\/\/bmcmusculoskeletdisord.biomedcentral.com\/articles\/10.1186\/s12891-025-09145-2#Fig1\" rel=\"nofollow noopener\" target=\"_blank\">1<\/a>).<\/p>\n<p>Fig. 1<a class=\"c-article-section__figure-link\" data-test=\"img-link\" data-track=\"click\" data-track-label=\"image\" data-track-action=\"view figure\" href=\"https:\/\/bmcmusculoskeletdisord.biomedcentral.com\/articles\/10.1186\/s12891-025-09145-2\/figures\/1\" rel=\"nofollow noopener\" target=\"_blank\"><img decoding=\"async\" aria-describedby=\"Fig1\" src=\"https:\/\/www.newsbeep.com\/ca\/wp-content\/uploads\/2025\/10\/12891_2025_9145_Fig1_HTML.png\" alt=\"figure 1\" loading=\"lazy\" width=\"685\" height=\"120\"\/><\/a><\/p>\n<p>Illustrates the outside-in suture shuttle repair technique, utilizing a 16-gauge intravenous cannula and a small posteromedial knee incision<\/p>\n<p>Surgical techniques<\/p>\n<p>OI meniscal repair was performed in 63 cases, while AI meniscal repair was performed in 30 cases. A 16-gauge intravenous (IV) cannula and 2.0 non-absorbable Prolene sutures were prepared. A standard 16-gauge IV cannula needle was inserted through the skin into the medial compartment of the knee joint using transillumination for guidance. Once the needle penetrated the capsule and passed through the meniscal tear\u2014according to the planned suture configuration (vertical or horizontal mattress)\u2014the Prolene sutures were retrieved to the outer surface of the knee via the anteromedial portal.<\/p>\n<p>The Fiber-Wire knot was secured to the loop of the 2.0 Prolene suture and advanced to the posterior aspect of the knee. Subsequently, a small incision and tunnel were created on the capsule. A 16-gauge needle was then inserted through the pre-formed tunnel and directed appropriately toward the meniscal tear. The 2.0 Prolene suture within the needle was retrieved through the anteromedial portal to the anterior surface of the knee. The Prolene loop was tied to the anterior end of the 2.0 Fiber-Wire and transported back to the posteromedial aspect of the knee (Fig. <a data-track=\"click\" data-track-label=\"link\" data-track-action=\"figure anchor\" href=\"http:\/\/bmcmusculoskeletdisord.biomedcentral.com\/articles\/10.1186\/s12891-025-09145-2#Fig1\" rel=\"nofollow noopener\" target=\"_blank\">1<\/a>).<\/p>\n<p>In the final step, the Fiber-Wire was securely tied and fixed to the outer surface of the capsule [<a data-track=\"click\" data-track-action=\"reference anchor\" data-track-label=\"link\" data-test=\"citation-ref\" aria-label=\"Reference 5\" title=\"Cho JH. A modified outside-in suture technique for repair of the middle segment of the meniscus using a spinal needle. Knee Surg Relat Res. 2014;26(1):43\u20137.\" href=\"http:\/\/bmcmusculoskeletdisord.biomedcentral.com\/articles\/10.1186\/s12891-025-09145-2#ref-CR5\" id=\"ref-link-section-d23746538e638\" rel=\"nofollow noopener\" target=\"_blank\">5<\/a>, <a data-track=\"click\" data-track-action=\"reference anchor\" data-track-label=\"link\" data-test=\"citation-ref\" aria-label=\"Reference 13\" title=\"Joshi A, Basukala B, Singh N, Hama B, Bista R, Pradhan I. Outside-in repair of longitudinal tear of medial meniscus: suture shuttle technique. Arthrosc Tech. 2020;9(4):e407-17.\" href=\"http:\/\/bmcmusculoskeletdisord.biomedcentral.com\/articles\/10.1186\/s12891-025-09145-2#ref-CR13\" id=\"ref-link-section-d23746538e641\" rel=\"nofollow noopener\" target=\"_blank\">13<\/a>].The AI meniscus repair technique was performed using a preloaded meniscal repair device (FasT-Fix), which was inserted through the working portal. The first suture anchor was deployed inside the joint to secure the meniscal tissue, followed by the placement of the second anchor at the desired location. Finally, the pre-tied sliding knot was tightened to approximate the tear edges [<a data-track=\"click\" data-track-action=\"reference anchor\" data-track-label=\"link\" data-test=\"citation-ref\" aria-label=\"Reference 1\" title=\"Ashish S, Ravindra C, Aditya D, Ashish P. Outcome after arthroscopic meniscal repair. D Y Patil J Health Sci. 2024;12(3):91\u20137.\" href=\"http:\/\/bmcmusculoskeletdisord.biomedcentral.com\/articles\/10.1186\/s12891-025-09145-2#ref-CR1\" id=\"ref-link-section-d23746538e644\" rel=\"nofollow noopener\" target=\"_blank\">1<\/a>].<\/p>\n<p>Data collection<\/p>\n<p>Additionally, demographic characteristics, including age, sex, history of previous knee surgeries, and tear zone location, were recorded. Postoperative complications such as deep vein thrombosis, saphenous nerve palsy, septic arthritis, or medial knee pain requiring second-look surgery were also documented.<\/p>\n<p>At a minimum follow-up of six months postoperatively, patients completed a subjective questionnaire to assess clinical outcomes at the last follow-up. The evaluation included the Knee Injury and Osteoarthritis Outcome Score (KOOS), the Tegner-Lysholm Knee Scoring Scale (TLKS), and the International Knee Documentation Committee (IKDC) score. Clinical outcomes were analyzed using the Minimal Clinically Important Difference (MCID) values for each measure [<a data-track=\"click\" data-track-action=\"reference anchor\" data-track-label=\"link\" data-test=\"citation-ref\" aria-label=\"Reference 15\" title=\"Maheshwer B, Wong SE, Polce EM, et al. Establishing the minimal clinically important difference and patient-acceptable symptomatic state after arthroscopic meniscal repair and associated variables for achievement. Arthroscopy: The Journal of Arthroscopic &amp; Related Surgery. 2021;37(12):3479\u201386.\" href=\"http:\/\/bmcmusculoskeletdisord.biomedcentral.com\/articles\/10.1186\/s12891-025-09145-2#ref-CR15\" id=\"ref-link-section-d23746538e658\" rel=\"nofollow noopener\" target=\"_blank\">15<\/a>].<\/p>\n<p>Rehabilitation<\/p>\n<p>During the first three weeks, knee flexion was restricted to 90\u00b0, with full extension being the primary goal. Patient mobilized with knee brace and double crutches. Weight-bearing was not permitted during this period. Early rehabilitation exercises included straight leg raises, hip abduction, and ankle pumps. From week 3 to week 6, partial weight-bearing was gradually introduced, and range of motion (ROM) and stretching exercises were performed to achieve at least 120\u00b0 of knee flexion. The knee brace lock was removed as stability improved. After week 6, the use of the brace and crutches was discontinued. Stationary cycling was initiated to facilitate the transition to functional activities. Strengthening exercises were progressively advanced to improve muscle endurance and joint stability. Patients were advised to return to unrestricted sports activities between 4 and 6 months postoperatively, depending on individual recovery and adherence to the rehabilitation protocol.<\/p>\n<p>Statistical analysis<\/p>\n<p>Data analysis was performed using \u2018\u2019IBM SPSS Statistics 26\u2019\u2019. Categorical independent variables were presented as frequencies and percentages with cross-tabulations. Their distributions were compared using \u2018\u2019Chi-Square Test\u2019\u2019 or \u2018\u2019Fisher\u2019s Exact Test\u2019\u2019 method. The suitability of continuous variables for normal distribution was investigated using graphical examination (Q-Q Plot), normality tests (Shapiro-Wilk) and sample size. Independent group comparisons of variables conforming to normal distribution were made with the \u2018\u2019t test\u2019\u2019 and presented with mean and standard deviation. For variables not conforming to normal distribution, the \u2018\u2019Mann Whitney\u2019\u2019 test was used and presented with median (min-max). For the difference in measurements taken before and after surgery, ANCOVA analysis was performed for repeated measurements in the comparisons between the groups and correction was made according to age, crude and estimated marginal means were used to assess the patient reported outcomes pre- and post-operatively. Adjusted means are presented. Effect sizes are presented as partial eta squared. In all statistical comparison tests, type-1 error margin was determined as \u03b1:0.05 and tested as two-tailed. The MCID was calculated using a distribution-based approach, employing the 0.5 standard deviation (SD) method for each outcome measure (IKDC, KOOS, TLKS). Preoperative SD values were used to determine MCID thresholds for both the outside-in (OI) and all-inside (AI) groups [<a data-track=\"click\" data-track-action=\"reference anchor\" data-track-label=\"link\" data-test=\"citation-ref\" aria-label=\"Reference 25\" title=\"Watabe T, Sengoku T, Kubota M, Sakurai G, Yoshida S, Taniguchi Y. Knee injury and osteoarthritis outcome score and knee society score for the minimal clinically important differences after cruciate-retaining total knee arthroplasty: two-year follow up. Knee. 2025;53:176\u201382.\" href=\"http:\/\/bmcmusculoskeletdisord.biomedcentral.com\/articles\/10.1186\/s12891-025-09145-2#ref-CR25\" id=\"ref-link-section-d23746538e678\" rel=\"nofollow noopener\" target=\"_blank\">25<\/a>].<\/p>\n","protected":false},"excerpt":{"rendered":"Patient selection and groups This retrospective study was conducted following approval from the local ethics committee. A total&hellip;\n","protected":false},"author":2,"featured_media":212543,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[10],"tags":[103247,49,48,4603,84,2987,103245,103248,91953,103246,31882,2989,3171],"class_list":["post-212542","post","type-post","status-publish","format-standard","has-post-thumbnail","category-health","tag-all-inside-repair","tag-ca","tag-canada","tag-epidemiology","tag-health","tag-internal-medicine","tag-medial-meniscus-tear","tag-minimal-clinically-important-difference","tag-orthopedics","tag-outside-in-repair","tag-rehabilitation","tag-rheumatology","tag-sports-medicine"],"_links":{"self":[{"href":"https:\/\/www.newsbeep.com\/ca\/wp-json\/wp\/v2\/posts\/212542","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.newsbeep.com\/ca\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.newsbeep.com\/ca\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/ca\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/ca\/wp-json\/wp\/v2\/comments?post=212542"}],"version-history":[{"count":0,"href":"https:\/\/www.newsbeep.com\/ca\/wp-json\/wp\/v2\/posts\/212542\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/ca\/wp-json\/wp\/v2\/media\/212543"}],"wp:attachment":[{"href":"https:\/\/www.newsbeep.com\/ca\/wp-json\/wp\/v2\/media?parent=212542"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.newsbeep.com\/ca\/wp-json\/wp\/v2\/categories?post=212542"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.newsbeep.com\/ca\/wp-json\/wp\/v2\/tags?post=212542"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}