{"id":362219,"date":"2025-12-22T18:38:08","date_gmt":"2025-12-22T18:38:08","guid":{"rendered":"https:\/\/www.newsbeep.com\/ca\/362219\/"},"modified":"2025-12-22T18:38:08","modified_gmt":"2025-12-22T18:38:08","slug":"discovery-of-the-most-intron-rich-eukaryotic-genome","status":"publish","type":"post","link":"https:\/\/www.newsbeep.com\/ca\/362219\/","title":{"rendered":"Discovery of the most intron-rich eukaryotic genome"},"content":{"rendered":"<p>                <a href=\"https:\/\/www.eurekalert.org\/multimedia\/1107963\" rel=\"nofollow noopener\" target=\"_blank\"><\/p>\n<p>                    <img decoding=\"async\" src=\"https:\/\/www.newsbeep.com\/ca\/wp-content\/uploads\/2025\/12\/1766428688_118_Public.jpeg\" alt=\"A unicellular marine alga with a highly intron-rich genome\"\/><\/p>\n<p>                <\/a><\/p>\n<p>image:\u00a0<\/p>\n<p>A light microscopy image of the chlorarachniophyte Amorphochlora amoebiformis<\/p>\n<p>                  <a href=\"https:\/\/www.eurekalert.org\/multimedia\/1107963\" rel=\"nofollow noopener\" target=\"_blank\">view more\u00a0<\/a><\/p>\n<p class=\"credit\">Credit: Yoshihisa Hirakawa<\/p>\n<p>Tsukuba, Japan\u2014The advent of next-generation sequencing technologies has accelerated genome analysis across diverse eukaryotic lineages. In particular, long-read sequencing facilitates the assembly of large, complex genomes containing a high proportion of repetitive elements.<\/p>\n<p>In this study, researchers used long-read sequencing to decode the nuclear genome of\u00a0Amorphochlora amoebiformis, revealing an approximate length of 214 million base pairs that encodes about 17,500 proteins, with introns accounting for 74% of the genome sequence. Compared with other eukaryotic genomes, the proportion of introns is extremely high. Since a closely related chlorarachniophyte species,\u00a0Bigelowiella natans, has an intron content of around 30%, the extensive intron gains observed in the nuclear genome of\u00a0A. amoebiformis\u00a0are inferred to have occurred independently during its evolution. Although the reason for this increase remains unknown, this study provides important insights into the evolutionary dynamics and potential functional roles of introns in eukaryotic genomes.<\/p>\n<p>###<br \/>This work was funded by the Japan Society for the Promotion of Science (JSPS) KAKENHI Grant Numbers 21K06285 and 25K02093, the Institute for Fermentation, Osaka (LA-2022-011), and the Sasakawa Scientific Research Grant from the Japan Science Society (2023-5024).<\/p>\n<p>\u00a0<\/p>\n<p>Original Paper<\/p>\n<p>Title of original paper:<br \/>Nuclear genome sequencing reveals the highly intron-rich architecture of the chlorarachniophyte alga\u00a0Amorphochlora amoebiformis<\/p>\n<p>Journal:<br \/>DNA Research<\/p>\n<p>DOI:<br \/><a href=\"https:\/\/doi.org\/10.1093\/dnares\/dsaf035\" target=\"_blank\" rel=\"nofollow noopener\">10.1093\/dnares\/dsaf035<\/a><\/p>\n<p>Correspondence<\/p>\n<p><a href=\"https:\/\/trios.tsukuba.ac.jp\/en\/researcher\/0000003318\" target=\"_blank\" rel=\"nofollow noopener\">Assistant Professor HIRAKAWA, Yoshihisa<\/a><br \/>Institute of Life and Environmental Sciences, University of Tsukuba<\/p>\n<p>Related Link<\/p>\n<p><a href=\"https:\/\/www.life.tsukuba.ac.jp\/en\/\" target=\"_blank\" rel=\"nofollow noopener\">Institute of Life and Environmental Sciences<\/a><\/p>\n<p>                            Article Title<\/p>\n<p>Nuclear genome sequencing reveals the highly intron-rich architecture of the chlorarachniophyte alga Amorphochlora amoebiformis<\/p>\n<p>                            Article Publication Date<\/p>\n<p>28-Nov-2025<\/p>\n<p>Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.<\/p>\n","protected":false},"excerpt":{"rendered":"image:\u00a0 A light microscopy image of the chlorarachniophyte Amorphochlora amoebiformis view more\u00a0 Credit: Yoshihisa Hirakawa Tsukuba, Japan\u2014The advent&hellip;\n","protected":false},"author":2,"featured_media":362220,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[7],"tags":[49,48,66],"class_list":{"0":"post-362219","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-science","8":"tag-ca","9":"tag-canada","10":"tag-science"},"_links":{"self":[{"href":"https:\/\/www.newsbeep.com\/ca\/wp-json\/wp\/v2\/posts\/362219","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.newsbeep.com\/ca\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.newsbeep.com\/ca\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/ca\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/ca\/wp-json\/wp\/v2\/comments?post=362219"}],"version-history":[{"count":0,"href":"https:\/\/www.newsbeep.com\/ca\/wp-json\/wp\/v2\/posts\/362219\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/ca\/wp-json\/wp\/v2\/media\/362220"}],"wp:attachment":[{"href":"https:\/\/www.newsbeep.com\/ca\/wp-json\/wp\/v2\/media?parent=362219"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.newsbeep.com\/ca\/wp-json\/wp\/v2\/categories?post=362219"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.newsbeep.com\/ca\/wp-json\/wp\/v2\/tags?post=362219"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}