A Mayo Clinic study found that a single 25 mg dose of a combination of amphetamine-dextroamphetamine salts (Adderall) can have measurable cardiovascular effects in healthy young adults. The study aimed to better understand how the stimulant affects those who use it without a medical prescription.<\/p>\n
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The primary objective of our study was to investigate how a single dose of Adderall acutely affects cardiovascular hemodynamics – blood pressure and heart rate – and sympathetic activity in young adults who do not have a medical indication for the medication.”<\/p>\n
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Anna Svatikova, M.D., Ph.D., Mayo Clinic cardiologist and senior author of the study<\/p>\n
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While Adderall is safe and effective when prescribed and monitored for ADHD, Dr. Svatikova says the risks of unsupervised use are often underestimated.<\/p>\n
“We have seen an increase in nonmedical Adderall use, but many users are unaware that it can place acute stress on the cardiovascular system,” says Dr. Svatikova.<\/p>\n
“Adderall is sometimes used without a prescription outside of a medical setting,” she says. “We found that even in individuals with no prior exposure, a 25 mg dose triggers significant increases in blood pressure, heart rate and activation of the body’s stress-response system.”<\/p>\n
Researchers also noted that Adderall caused the heart rate to spike much higher than usual just by standing up.<\/p>\n
“The average heart rate increase on standing was 19 beats per minute before Adderall. After taking Adderall, that response doubled to 38 beats per minute,” says Kiran Somers, D.O., a resident physician in the Department of Family Medicine, Mayo Clinic Eau Claire, and lead author of the study.<\/p>\n
Researchers say the findings highlight how stimulant effects can be in individuals who are not accustomed to the medication.<\/p>\n
“These results demonstrate measurable, acute cardiovascular effects of Adderall used by those not regularly using Adderall prescribed for specific medical reasons,” says Dr. Somers.<\/p>\n
The researchers underscore that these findings apply to off-prescription use and do not reflect the long-term, supervised use of the medication for the treatment of ADHD. Dr. Svatikova shares that these findings should not be extrapolated to the long-term, supervised use of Adderall for the treatment of ADHD or other specific medical conditions, where the therapeutic benefits are well established and significant.<\/p>\n","protected":false},"excerpt":{"rendered":"A Mayo Clinic study found that a single 25 mg dose of a combination of amphetamine-dextroamphetamine salts (Adderall)…\n","protected":false},"author":2,"featured_media":85413,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[10],"tags":[169650,202717,2768,8431,49,48,84,2776,419,2618],"class_list":["post-509493","post","type-post","status-publish","format-standard","has-post-thumbnail","category-health","tag-adderall","tag-amphetamine","tag-blood","tag-blood-pressure","tag-ca","tag-canada","tag-health","tag-heart","tag-heart-rate","tag-stress"],"_links":{"self":[{"href":"https:\/\/www.newsbeep.com\/ca\/wp-json\/wp\/v2\/posts\/509493","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.newsbeep.com\/ca\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.newsbeep.com\/ca\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/ca\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/ca\/wp-json\/wp\/v2\/comments?post=509493"}],"version-history":[{"count":0,"href":"https:\/\/www.newsbeep.com\/ca\/wp-json\/wp\/v2\/posts\/509493\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/ca\/wp-json\/wp\/v2\/media\/85413"}],"wp:attachment":[{"href":"https:\/\/www.newsbeep.com\/ca\/wp-json\/wp\/v2\/media?parent=509493"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.newsbeep.com\/ca\/wp-json\/wp\/v2\/categories?post=509493"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.newsbeep.com\/ca\/wp-json\/wp\/v2\/tags?post=509493"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}