{"id":520714,"date":"2026-03-07T16:16:09","date_gmt":"2026-03-07T16:16:09","guid":{"rendered":"https:\/\/www.newsbeep.com\/ca\/520714\/"},"modified":"2026-03-07T16:16:09","modified_gmt":"2026-03-07T16:16:09","slug":"what-we-know-about-the-fungus-behind-hospital-deaths-sciencealert","status":"publish","type":"post","link":"https:\/\/www.newsbeep.com\/ca\/520714\/","title":{"rendered":"What We Know About The Fungus Behind Hospital Deaths : ScienceAlert"},"content":{"rendered":"<p>A common mold has killed two people and left four others seriously ill at one of Sydney&#8217;s largest hospitals.<\/p>\n<p>Health authorities <a href=\"https:\/\/cdn.theconversation.com\/static_files\/files\/4139\/260225_STATEMENT_-_RPA_fungal_cluster2.pdf?1772159264\" rel=\"nofollow noopener\" target=\"_blank\">are investigating<\/a> a cluster of fungal infections at the Royal Prince Alfred Hospital&#8217;s transplant unit.<\/p>\n<p>Six patients developed infections between October and December 2025 after being exposed to Aspergillus, a common mold found in soil, plants, dust, and damp environments.<\/p>\n<p>In a statement, a hospital spokesperson suggested the mold may have been present at nearby construction sites, part of the hospital&#8217;s A$940 million redevelopment.<\/p>\n<p>So what is Aspergillus? And should you be concerned?<\/p>\n<p><img decoding=\"async\" src=\"https:\/\/www.newsbeep.com\/ca\/wp-content\/uploads\/2026\/03\/file-20260227-57-3gyc0y.jpeg\" loading=\"lazy\"\/>(Oliver Morton)It&#8217;s a common mold?<\/p>\n<p>Yes. Aspergillus molds are a type of filamentous fungi, meaning they form long chains, and are usually found in soil, plants, and damp areas.<\/p>\n<p>This type of mold is usually harmless to healthy people. But it can cause a severe respiratory disease called <a href=\"https:\/\/www.cdc.gov\/aspergillosis\/index.html\" rel=\"nofollow noopener\" target=\"_blank\">aspergillosis<\/a>. Aspergillosis affects about <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK482241\/\" rel=\"nofollow noopener\" target=\"_blank\">250,000 people<\/a> around the world.<\/p>\n<p>How can Aspergillus harm?<\/p>\n<p>This type of mold produces airborne spores, which people may inhale into their lungs.<\/p>\n<p>There, these spores can cause an infection in the smallest chambers of the lungs. This is because they release toxins and enzymes that <a href=\"https:\/\/doi.org\/10.1136\/thoraxjnl-2014-206291\" rel=\"nofollow noopener\" target=\"_blank\">damage lung tissue<\/a>. These spores can spread to other parts of the body, such as the brain, kidneys, heart, or skin, causing further infection.<\/p>\n<p><a href=\"https:\/\/www.sciencealert.com\/newsletter?utm_source=promo_generic_health\" rel=\"nofollow noopener\" target=\"_blank\"><img decoding=\"async\" src=\"https:\/\/www.newsbeep.com\/ca\/wp-content\/uploads\/2025\/12\/Generic-Health-Promo-Final-642x273.jpg\" alt=\"Subscribe to ScienceAlert's free fact-checked newsletter\" width=\"642\" height=\"273\" class=\"alignnone wp-image-182810 size-medium\"   loading=\"lazy\"\/><\/a><\/p>\n<p>Symptoms of an infection include  <a href=\"https:\/\/www.sciencealert.com\/fever\" class=\"lar_link lar_link_outgoing\" data-linkid=\"73066\" data-postid=\"193840\" rel=\"nofollow noopener\" target=\"_self\">fever<\/a>, cough, and chest pain. You may have trouble breathing or might start coughing up blood. Aspergillus can also cause skin and eye infections.<\/p>\n<p>Who is most vulnerable?<\/p>\n<p>Our immune systems can generally fight Aspergillus infections. But people with weakened immune systems have a <a href=\"https:\/\/doi.org\/10.1128\/CMR.00140-18\" rel=\"nofollow noopener\" target=\"_blank\">much higher risk<\/a> of developing an infection.<\/p>\n<p>These include <a href=\"https:\/\/doi.org\/10.1136\/thoraxjnl-2014-206291\" rel=\"nofollow noopener\" target=\"_blank\">people having chemotherapy<\/a>, corticosteroid treatment, or organ or  <a href=\"https:\/\/www.sciencealert.com\/stem-cells\" class=\"lar_link lar_link_outgoing\" data-linkid=\"73034\" data-postid=\"193840\" rel=\"nofollow noopener\" target=\"_self\">stem cell<\/a> transplants. Transplant patients are particularly vulnerable.<\/p>\n<p>This is because their immune system must be deliberately weakened to stop their body rejecting the transplanted organ. If they somehow inhale Aspergillus spores, the fungus can more easily take hold in their lungs.<\/p>\n<p>Dormant spores in the lungs of transplant patients may <a href=\"https:\/\/doi.org\/10.1016\/j.mib.2019.04.00\" rel=\"nofollow noopener\" target=\"_blank\">also cause infection<\/a> when the spores are activated. But health authorities did not indicate this occurred at the Sydney hospital.<\/p>\n<p>One <a href=\"https:\/\/www.cdc.gov\/aspergillosis\/statistics\/index.html\" rel=\"nofollow noopener\" target=\"_blank\">large US study<\/a> found just 59% of organ transplant recipients and 25% of stem cell transplant patients were still alive one year after developing invasive aspergillosis.<\/p>\n<p>People with asthma may develop allergies to Aspergillus even if their immune systems are healthy. And it can cause severe allergic reactions in people with <a href=\"https:\/\/www.mcri.edu.au\/impact\/a-z-child-adolescent-health\/c\/cystic-fibrosis\" rel=\"nofollow noopener\" target=\"_blank\">cystic fibrosis<\/a>, a genetic condition in which sticky mucus blocks their airways. People with other lung conditions such as tuberculosis,  <a href=\"https:\/\/www.sciencealert.com\/what-is-influenza\" class=\"lar_link lar_link_outgoing\" data-linkid=\"103478\" data-postid=\"193840\" rel=\"nofollow noopener\" target=\"_self\">influenza<\/a>, or COVID are also at a higher risk of developing an Aspergillus infection.<\/p>\n<p>What are the treatment options?<\/p>\n<p>Aspergillus can be treated with <a href=\"https:\/\/www.cdc.gov\/aspergillosis\/index.html\" rel=\"nofollow noopener\" target=\"_blank\">antifungal drugs<\/a> such as itraconazole and corticosteroids. This treatment is most effective when we detect the infection early.<\/p>\n<p>But researchers have identified strains of Aspergillus that don&#8217;t respond to this kind of treatment. So antifungal resistance is an urgent problem.<\/p>\n<p>What else do I need to know?<\/p>\n<p>Aspergillus infections are relatively uncommon in the general population. And they are rare in hospitals, where wards and rooms are usually fitted with <a href=\"https:\/\/www.islhd.health.nsw.gov.au\/sites\/default\/files\/IMACS\/InvasiveAspergillosisFactsheet.pdf\" rel=\"nofollow noopener\" target=\"_blank\">high-efficiency particulate air<\/a>, or HEPA, filters. These filters capture and remove potentially harmful particles from the air.<\/p>\n<p>Related: <a href=\"https:\/\/www.sciencealert.com\/hotter-climate-could-fuel-spread-of-dangerous-fungi-scientists-warn\" rel=\"nofollow noopener\" target=\"_blank\">Hotter Climate Could Fuel Spread of Dangerous Fungi, Scientists Warn<\/a><\/p>\n<p>However, construction work may disturb the soil near or around the hospital, releasing a high number of Aspergillus spores into the air. This increases the risk of hospitals having clusters of infection. It remains unclear whether this is what happened at the Royal Prince Alfred Hospital.<img decoding=\"async\" src=\"https:\/\/www.newsbeep.com\/ca\/wp-content\/uploads\/2026\/03\/1772900169_127_count.gif\" alt=\"The Conversation\" width=\"1\" height=\"1\" style=\"border: none !important; box-shadow: none !important; margin: 0 !important; max-height: 1px !important; max-width: 1px !important; min-height: 1px !important; min-width: 1px !important; opacity: 0 !important; outline: none !important; padding: 0 !important;\" referrerpolicy=\"no-referrer-when-downgrade\" loading=\"lazy\"\/>\n<\/p>\n<p><a href=\"https:\/\/theconversation.com\/profiles\/thomas-jeffries-1511629\" rel=\"nofollow noopener\" target=\"_blank\">Thomas Jeffries<\/a>, Senior Lecturer in Microbiology, <a href=\"https:\/\/theconversation.com\/institutions\/western-sydney-university-1092\" rel=\"nofollow noopener\" target=\"_blank\">Western Sydney University<\/a> and <a href=\"https:\/\/theconversation.com\/profiles\/charles-oliver-morton-2423921\" rel=\"nofollow noopener\" target=\"_blank\">Charles Oliver Morton<\/a>, Senior Lecturer in Medical Microbiology, <a href=\"https:\/\/theconversation.com\/institutions\/western-sydney-university-1092\" rel=\"nofollow noopener\" target=\"_blank\">Western Sydney University<\/a><\/p>\n<p>This article is republished from <a href=\"https:\/\/theconversation.com\" rel=\"nofollow noopener\" target=\"_blank\">The Conversation<\/a> under a Creative Commons license. Read the <a href=\"https:\/\/theconversation.com\/what-is-aspergillus-the-fungus-behind-recent-hospital-deaths-277067\" rel=\"nofollow noopener\" target=\"_blank\">original article<\/a>.<\/p>\n","protected":false},"excerpt":{"rendered":"A common mold has killed two people and left four others seriously ill at one of Sydney&#8217;s largest&hellip;\n","protected":false},"author":2,"featured_media":520715,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[10],"tags":[49,48,84],"class_list":{"0":"post-520714","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-health","8":"tag-ca","9":"tag-canada","10":"tag-health"},"_links":{"self":[{"href":"https:\/\/www.newsbeep.com\/ca\/wp-json\/wp\/v2\/posts\/520714","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.newsbeep.com\/ca\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.newsbeep.com\/ca\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/ca\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/ca\/wp-json\/wp\/v2\/comments?post=520714"}],"version-history":[{"count":0,"href":"https:\/\/www.newsbeep.com\/ca\/wp-json\/wp\/v2\/posts\/520714\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/ca\/wp-json\/wp\/v2\/media\/520715"}],"wp:attachment":[{"href":"https:\/\/www.newsbeep.com\/ca\/wp-json\/wp\/v2\/media?parent=520714"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.newsbeep.com\/ca\/wp-json\/wp\/v2\/categories?post=520714"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.newsbeep.com\/ca\/wp-json\/wp\/v2\/tags?post=520714"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}