{"id":537670,"date":"2026-03-15T09:02:09","date_gmt":"2026-03-15T09:02:09","guid":{"rendered":"https:\/\/www.newsbeep.com\/ca\/537670\/"},"modified":"2026-03-15T09:02:09","modified_gmt":"2026-03-15T09:02:09","slug":"untreatable-migraine-cases-may-drop-to-2","status":"publish","type":"post","link":"https:\/\/www.newsbeep.com\/ca\/537670\/","title":{"rendered":"Untreatable migraine cases &#8216;may drop to 2%&#8217;"},"content":{"rendered":"<p class=\"mb-4 text-lg md:leading-8 break-words\">A leading neurologist believes migraines will never be &#8220;cured in my lifetime&#8221;, but the number of untreatable patients in the UK could drop to about 2% of those with the condition.<\/p>\n<p class=\"mb-4 text-lg md:leading-8 break-words\">Prof Fayyaz Ahmed, 65, has spent nearly 30 years advancing headache and migraine research and treatment. He set up a pioneering UK clinic using Botox injections to treat migraines on the NHS and has treated 5,000 patients since it opened in Hull in 2012.<\/p>\n<p class=\"mb-4 text-lg md:leading-8 break-words\">The consultant, who has published a book about his career, thinks the next generation of drugs may reduce the proportion of migraine sufferers who have not responded well to current medications.<\/p>\n<p class=\"mb-4 text-lg md:leading-8 break-words\">According to the NHS, migraines affect <a href=\"https:\/\/www.nhs.uk\/conditions\/migraine\/\" rel=\"nofollow noopener\" target=\"_blank\" data-ylk=\"slk:six million people in the UK;elm:context_link;itc:0;sec:content-canvas\" data-yga=\"{&quot;yLinkElement&quot;:&quot;context_link&quot;,&quot;yModuleName&quot;:&quot;content-canvas&quot;,&quot;yLinkText&quot;:&quot;six million people in the UK&quot;}\" class=\"link \">six million people in the UK<\/a>.<\/p>\n<p class=\"mb-4 text-lg md:leading-8 break-words\">Migraines are more severe than headaches and are often accompanied by other symptoms, such as dizziness, sensitivity to light, visual disturbances, nausea and vomiting, and difficulty speaking.<\/p>\n<p class=\"mb-4 text-lg md:leading-8 break-words\">The pain may be throbbing in one side of the head and can last several days.<\/p>\n<p class=\"mb-4 text-lg md:leading-8 break-words\">The Migraine Trust, for which Ahmed is an ambassador, says the condition is <a href=\"https:\/\/migrainetrust.org\/news\/migraine-has-impacted-pretty-much-every-aspect-of-my-life-women-share-their-experiences\/\" rel=\"nofollow noopener\" target=\"_blank\" data-ylk=\"slk:two to three times more common in women;elm:context_link;itc:0;sec:content-canvas\" data-yga=\"{&quot;yLinkElement&quot;:&quot;context_link&quot;,&quot;yModuleName&quot;:&quot;content-canvas&quot;,&quot;yLinkText&quot;:&quot;two to three times more common in women&quot;}\" class=\"link \">two to three times more common in women<\/a> than men.<\/p>\n<p class=\"mb-4 text-lg md:leading-8 break-words\">According to Ahmed, treatments such as Botox and other drugs, which <a href=\"https:\/\/migrainetrust.org\/live-with-migraine\/healthcare\/treatments\/calcitonin-gene-related-peptide-monoclonal-antibodies\/\" rel=\"nofollow noopener\" target=\"_blank\" data-ylk=\"slk:target a chemical in the brain called calcitonin gene-related peptide;elm:context_link;itc:0;sec:content-canvas\" data-yga=\"{&quot;yLinkElement&quot;:&quot;context_link&quot;,&quot;yModuleName&quot;:&quot;content-canvas&quot;,&quot;yLinkText&quot;:&quot;target a chemical in the brain called calcitonin gene-related peptide&quot;}\" class=\"link \">target a chemical in the brain called calcitonin gene-related peptide<\/a> (CGRP) in order to block pain in the lead-up to a migraine attack, have so far helped about 95% of patients with the condition.<\/p>\n<p class=\"mb-4 text-lg md:leading-8 break-words\">&#8220;In my lifetime I cannot see any cure coming out because we still don&#8217;t know what causes migraines,&#8221; he says.<\/p>\n<p><img alt=\"A man in a dark suit speaking to a woman in a pink floral dress and hat at an outdoor formal event. Other guests in smart attire stand nearby on a grassy lawn, with a white marquee tent in the background.\" loading=\"lazy\" width=\"724\" height=\"407\" decoding=\"async\" data-nimg=\"1\" class=\"rounded-lg\" style=\"color:transparent\" src=\"https:\/\/www.newsbeep.com\/ca\/wp-content\/uploads\/2026\/03\/67691bbb9a94ece1b79f6e449e219989.jpeg\"\/><\/p>\n<p>Ahmed discusses his work with Sophie, Duchess of Edinburgh, at a royal garden party at Buckingham Palace in 2025 [Hull University Teaching Hospitals NHS Trust]<\/p>\n<p class=\"mb-4 text-lg md:leading-8 break-words\">Current drugs control symptoms and triggers, which means sufferers get far fewer migraine days and can continue with daily life.<\/p>\n<p class=\"mb-4 text-lg md:leading-8 break-words\">While no research is close to finding the root cause, oestrogen is a major trigger of migraines and family genetics is also a factor, Ahmed explains.<\/p>\n<p class=\"mb-4 text-lg md:leading-8 break-words\">He says a new generation of drugs being developed in Denmark means the number of untreatable migraine cases could &#8220;come down to about 2 to 3%&#8221;.<\/p>\n<p class=\"mb-4 text-lg md:leading-8 break-words\">Ahmed, who is now partially retired, is also an honorary advisor with the British Association for the Study of Headache.<\/p>\n<p class=\"mb-4 text-lg md:leading-8 break-words\">He says he faced some scepticism when he suggested establishing the UK&#8217;s first dedicated NHS clinic to treat patients with Botox.<\/p>\n<p class=\"mb-4 text-lg md:leading-8 break-words\">&#8220;I wanted to be the first one to set up a clinic for the benefit of the patients and I managed to do that and that is, I feel, quite a big achievement for me.&#8221;<\/p>\n<p class=\"mb-4 text-lg md:leading-8 break-words\">Now, 14 years on, Ahmed says he has turned his attention to &#8220;training the next generation of doctors&#8221;.<\/p>\n<p class=\"mb-4 text-lg md:leading-8 break-words\">He is also raising money via the proceeds from the sale of his new book to fund research by PhD students.<\/p>\n<p class=\"mb-4 text-lg md:leading-8 break-words\">The book, <a href=\"https:\/\/www.nlg.nhs.uk\/news\/world-leading-neurologist-and-headache-specialist-seeks-to-inspire-next-generation\/\" rel=\"nofollow noopener\" target=\"_blank\" data-ylk=\"slk:titled Beneath the Dust;elm:context_link;itc:0;sec:content-canvas\" data-yga=\"{&quot;yLinkElement&quot;:&quot;context_link&quot;,&quot;yModuleName&quot;:&quot;content-canvas&quot;,&quot;yLinkText&quot;:&quot;titled Beneath the Dust&quot;}\" class=\"link \">titled Beneath the Dust<\/a>, recounts his childhood in Pakistan and journey from medical school to the UK, as well as his work and research in the field. Proceeds will go to the Migraine Trust.<\/p>\n<p class=\"mb-4 text-lg md:leading-8 break-words\">Ahmed says reading positive comments from patients on social media makes him &#8220;feel very happy that I have been a part of people&#8217;s life changing experience&#8221;, knowing he has made a difference to their wellbeing.<\/p>\n<p class=\"mb-4 text-lg md:leading-8 break-words\">Listen to highlights from <a href=\"https:\/\/www.bbc.co.uk\/programmes\/p0cghg97\/clips?xtor=AL-72-%5Bpartner%5D-%5Byahoo.north.america%5D-%5Blink%5D-%5Bnews%5D-%5Bbizdev%5D-%5Bisapi%5D\" rel=\"nofollow noopener\" target=\"_blank\" data-ylk=\"slk:Hull and East Yorkshire on BBC Sounds;elm:context_link;itc:0;sec:content-canvas\" data-yga=\"{&quot;yLinkElement&quot;:&quot;context_link&quot;,&quot;yModuleName&quot;:&quot;content-canvas&quot;,&quot;yLinkText&quot;:&quot;Hull and East Yorkshire on BBC Sounds&quot;}\" class=\"link \">Hull and East Yorkshire on BBC Sounds<\/a>, watch the <a href=\"https:\/\/www.bbc.co.uk\/programmes\/b007tp3n?xtor=AL-72-%5Bpartner%5D-%5Byahoo.north.america%5D-%5Blink%5D-%5Bnews%5D-%5Bbizdev%5D-%5Bisapi%5D\" rel=\"nofollow noopener\" target=\"_blank\" data-ylk=\"slk:latest episode of Look North;elm:context_link;itc:0;sec:content-canvas\" data-yga=\"{&quot;yLinkElement&quot;:&quot;context_link&quot;,&quot;yModuleName&quot;:&quot;content-canvas&quot;,&quot;yLinkText&quot;:&quot;latest episode of Look North&quot;}\" class=\"link \">latest episode of Look North<\/a>.<\/p>\n<p class=\"mb-4 text-lg md:leading-8 break-words\">Download the BBC News app from the <a href=\"https:\/\/apps.apple.com\/gb\/app\/bbc-news-uk-world-stories\/id377382255?is_retargeting=true&amp;source_caller=ui&amp;shortlink=6mc9icpm&amp;c=BBC_app_install_house_ad_uk&amp;pid=Generic%20article%20link_Apple&amp;af_xp=custom&amp;af_reengagement_window=30d\" rel=\"nofollow noopener\" target=\"_blank\" data-ylk=\"slk:App Store;elm:context_link;itc:0;sec:content-canvas\" data-yga=\"{&quot;yLinkElement&quot;:&quot;context_link&quot;,&quot;yModuleName&quot;:&quot;content-canvas&quot;,&quot;yLinkText&quot;:&quot;App Store&quot;}\" class=\"link \">App Store<\/a> for iPhone and iPad or <a href=\"https:\/\/play.google.com\/store\/apps\/details?id=bbc.mobile.news.uk&amp;hl=en_GB&amp;is_retargeting=true&amp;source_caller=ui&amp;shortlink=ser4scwo&amp;c=BBC_app_install_house_ad_uk&amp;pid=Generic%20article%20link_Android&amp;af_xp=custom&amp;af_reengagement_window=30d\" rel=\"nofollow noopener\" target=\"_blank\" data-ylk=\"slk:Google Play;elm:context_link;itc:0;sec:content-canvas\" data-yga=\"{&quot;yLinkElement&quot;:&quot;context_link&quot;,&quot;yModuleName&quot;:&quot;content-canvas&quot;,&quot;yLinkText&quot;:&quot;Google Play&quot;}\" class=\"link \">Google Play<\/a> for Android devices<\/p>\n<p>More on this storyRelated internet links<\/p>\n","protected":false},"excerpt":{"rendered":"A leading neurologist believes migraines will never be &#8220;cured in my lifetime&#8221;, but the number of untreatable patients&hellip;\n","protected":false},"author":2,"featured_media":537671,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[10],"tags":[210266,49,48,210264,84,210265,142191,10569],"class_list":["post-537670","post","type-post","status-publish","format-standard","has-post-thumbnail","category-health","tag-botox-injections","tag-ca","tag-canada","tag-fayyaz-ahmed","tag-health","tag-migraine-trust","tag-nhs-humber-health-partnership","tag-patients"],"_links":{"self":[{"href":"https:\/\/www.newsbeep.com\/ca\/wp-json\/wp\/v2\/posts\/537670","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.newsbeep.com\/ca\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.newsbeep.com\/ca\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/ca\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/ca\/wp-json\/wp\/v2\/comments?post=537670"}],"version-history":[{"count":0,"href":"https:\/\/www.newsbeep.com\/ca\/wp-json\/wp\/v2\/posts\/537670\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/ca\/wp-json\/wp\/v2\/media\/537671"}],"wp:attachment":[{"href":"https:\/\/www.newsbeep.com\/ca\/wp-json\/wp\/v2\/media?parent=537670"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.newsbeep.com\/ca\/wp-json\/wp\/v2\/categories?post=537670"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.newsbeep.com\/ca\/wp-json\/wp\/v2\/tags?post=537670"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}