{"id":554118,"date":"2026-03-22T23:04:10","date_gmt":"2026-03-22T23:04:10","guid":{"rendered":"https:\/\/www.newsbeep.com\/ca\/554118\/"},"modified":"2026-03-22T23:04:10","modified_gmt":"2026-03-22T23:04:10","slug":"tooth-enamel-emerges-as-key-archive-of-ancient-biomolecules","status":"publish","type":"post","link":"https:\/\/www.newsbeep.com\/ca\/554118\/","title":{"rendered":"Tooth enamel emerges as key archive of ancient biomolecules"},"content":{"rendered":"<p>A new study has found that amino acids have survived inside fossil mammal teeth for 48 million years, extending the known lifespan of these molecules far beyond earlier limits.<\/p>\n<p>That durability turns tooth enamel into a far deeper archive of ancient diets, species relationships, and ecosystems than scientists had previously confirmed.<\/p>\n<p>Inside fossil tooth enamel<br \/>\n<a href=\"https:\/\/earthsnap.onelink.me\/3u5Q\/ags2loc4\" rel=\"noopener nofollow\" target=\"_blank\">&#13;<br \/>\n    <img decoding=\"async\" class=\"fit-picture\" loading=\"lazy\" src=\"https:\/\/www.newsbeep.com\/ca\/wp-content\/uploads\/2026\/01\/earthsnap-banner-news.webp.webp\" alt=\"EarthSnap\"\/>&#13;<br \/>\n<\/a><\/p>\n<p>Inside 72 fossil teeth from horses, rhinos, and elephant relatives, the molecules persisted across samples spanning tens of thousands to tens of millions of years.<\/p>\n<p>By analyzing those remains, Lucrezia Gatti at the Max Planck Institute for Chemistry (<a href=\"https:\/\/www.mpic.de\" target=\"_blank\" rel=\"noreferrer noopener nofollow\">MPIC<\/a>) documented how enamel shields a protected core of organic material.<\/p>\n<p>Across that span of time, most losses occurred early, while a smaller fraction remained stable for millions of years within the same teeth.<\/p>\n<p>That uneven survival points to a layered system of decay and protection, which sets up the need to explain how enamel preserves what other tissues lose.<\/p>\n<p>Why enamel lasts<\/p>\n<p>Tooth enamel lasts because it is almost entirely mineral, with only about one percent organic material left from tooth growth.<\/p>\n<p>As crystals harden, some residues become intra-crystalline, trapped inside the mineral itself, where water and microbes have fewer paths in.<\/p>\n<p>That sealed position also explains why East African <a href=\"https:\/\/www.nature.com\/articles\/s41586-025-09040-9\" target=\"_blank\" rel=\"noreferrer noopener nofollow\">enamel<\/a> yielded proteins 18 million years old, despite tropical heat.<\/p>\n<p>Those findings made enamel the obvious place to look for an even older molecular record.<\/p>\n<p>Early fossil decay<\/p>\n<p>Across all three mammal groups, amino acid levels dropped fast during the first 0.10 million years after burial.<\/p>\n<p>Depending on the <a href=\"https:\/\/www.earth.com\/news\/chemists-isolate-three-atom-aluminum-molecule-for-the-first-time\/\" rel=\"nofollow noopener\" target=\"_blank\">molecule<\/a>, that early drop meant losing 55 percent to 96 percent of the amino acids originally present in modern enamel.<\/p>\n<p>Once the more exposed material disappeared, the remaining pool changed far more slowly, which points to stronger protection deeper inside.<\/p>\n<p>That two-step story matters because researchers can now separate rapid early decay from the long survival of the best-hidden molecules.<\/p>\n<p>Age shapes decay patterns<\/p>\n<p>Burial setting mattered less than <a href=\"https:\/\/www.earth.com\/news\/new-dinosaur-age-bird-species-found-in-spain\/\" rel=\"nofollow noopener\" target=\"_blank\">age<\/a>, even when teeth came from lakes, rivers, peat bogs, coal seams, and rock fissures.<\/p>\n<p>Scientists call that burial backdrop a taphonomic setting, the place and conditions after death, and it was usually not decisive.<\/p>\n<p>Only lake deposits showed more overlap between young and old teeth, hinting that some local chemistry can blur the pattern.<\/p>\n<p>Even so, the overall result held firm: old teeth usually carried the stronger signal of loss, whatever the surrounding sediments.<\/p>\n<p>Which molecules fade<\/p>\n<p>Not all amino acids aged the same way, and some vanished much faster than others.<\/p>\n<p>Aspartic and glutamic acid groups fell especially hard because their structures break down more easily during long chemical wear.<\/p>\n<p>Serine also declined quickly, while leucine stayed relatively steady but told <a href=\"https:\/\/www.earth.com\/news\/antarctic-researchers-solve-long-standing-blood-falls-mystery\/\" rel=\"nofollow noopener\" target=\"_blank\">researchers<\/a> less about a tooth\u2019s age.<\/p>\n<p>Those different fates mean future work must choose molecules carefully instead of treating the whole surviving mix as equal.<\/p>\n<p>Horses held steadier<\/p>\n<p>Horse relatives held a steadier pattern than rhinos and elephant kin, both in modern teeth and <a href=\"https:\/\/www.earth.com\/news\/archaeopteryx-fossil-soft-tissue-preserved-flight-evolution-proves-darwin-right\/\" rel=\"nofollow noopener\" target=\"_blank\">fossil<\/a> ones.<\/p>\n<p>Their starting levels varied less from tooth to tooth, so later losses looked cleaner and easier to track.<\/p>\n<p>One striking case came from Messel in Germany, near Frankfurt, a former volcanic lake site known for exceptional fossil preservation, where 48-million-year-old horse-family enamel still resembled modern horses more than expected.<\/p>\n<p><a href=\"https:\/\/whc.unesco.org\/en\/list\/720\/\" target=\"_blank\" rel=\"noreferrer noopener nofollow\">Messel<\/a> is famous for exceptional fossil preservation, but the broader pattern did not depend on rare sites like that one.<\/p>\n<p>Reading time from teeth<\/p>\n<p>The team also tested whether amino acid patterns could estimate age, not just prove survival.<\/p>\n<p>A computer model predicted sample age with moderate accuracy, showing that some molecules changed more consistently than others.<\/p>\n<p>Certain amino acids also acted as reliable markers for estimating how old a tooth is because they changed in steady, predictable ways over time.<\/p>\n<p>That opens a practical path for dating teeth when other clues are weak, although the signal still varies by animal group.<\/p>\n<p>Beyond protein fragments<\/p>\n<p>Earlier enamel <a href=\"https:\/\/www.nature.com\/articles\/s42003-023-04744-y\" target=\"_blank\" rel=\"noreferrer noopener nofollow\">nitrogen<\/a> work had shown that tooth-bound nitrogen can track an animal\u2019s place in a food web.<\/p>\n<p>Because amino acids carry more specific chemical information, they could refine insights into diet and reveal seasonal changes.<\/p>\n<p>Researchers call that targeted protein work paleoproteomics, the study of ancient proteins, and enamel may become its best scouting tissue.<\/p>\n<p>A broad <a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC7810370\/\" target=\"_blank\" rel=\"noreferrer noopener nofollow\">review<\/a> had already shown that ancient protein studies work best when researchers can authenticate truly old molecules.<\/p>\n<p>Limits and next steps<\/p>\n<p>Even with this long survival, the study could not yet tell whether the molecules remain free or still sit inside protein fragments.<\/p>\n<p>That distinction matters because intact fragments can reveal ancestry, while single amino acids may work better for diet chemistry.<\/p>\n<p>Since MPIC\u2019s method needed only about one milligram of cleaned enamel, museums could test rare teeth before using harsher analyses.<\/p>\n<p>Future work will have to sort authentic residues from altered ones, then connect those molecules to species history and ecology.<\/p>\n<p>Broader scientific impact<\/p>\n<p>Fossil enamel now stands out as a durable source of biological detail that lasts far beyond earlier molecular limits.<\/p>\n<p>If researchers can separate the surviving compounds cleanly, teeth may reveal meals, seasons, and kinship from eras where genetic material no longer survives.<\/p>\n<p>The study is published in <a href=\"https:\/\/www.nature.com\/articles\/s42003-026-09716-6\" target=\"_blank\" rel=\"noreferrer noopener nofollow\">Communications Biology<\/a>.<\/p>\n<p>\u2014\u2013<\/p>\n<p>Like what you read?\u00a0<a href=\"https:\/\/www.earth.com\/subscribe\/\" target=\"_blank\" rel=\"noreferrer noopener nofollow\">Subscribe to our newsletter<\/a>\u00a0for engaging articles, exclusive content, and the latest updates.<\/p>\n<p>Check us out on\u00a0<a href=\"https:\/\/www.earth.com\/earthsnap\/\" target=\"_blank\" rel=\"noreferrer noopener nofollow\">EarthSnap<\/a>, a free app brought to you by\u00a0<a href=\"https:\/\/www.earth.com\/author\/eralls\/\" target=\"_blank\" rel=\"noreferrer noopener nofollow\">Eric Ralls<\/a>\u00a0and Earth.com.<\/p>\n<p>\u2014\u2013<\/p>\n","protected":false},"excerpt":{"rendered":"A new study has found that amino acids have survived inside fossil mammal teeth for 48 million years,&hellip;\n","protected":false},"author":2,"featured_media":554119,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[7],"tags":[49,48,66],"class_list":["post-554118","post","type-post","status-publish","format-standard","has-post-thumbnail","category-science","tag-ca","tag-canada","tag-science"],"_links":{"self":[{"href":"https:\/\/www.newsbeep.com\/ca\/wp-json\/wp\/v2\/posts\/554118","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.newsbeep.com\/ca\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.newsbeep.com\/ca\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/ca\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/ca\/wp-json\/wp\/v2\/comments?post=554118"}],"version-history":[{"count":0,"href":"https:\/\/www.newsbeep.com\/ca\/wp-json\/wp\/v2\/posts\/554118\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/ca\/wp-json\/wp\/v2\/media\/554119"}],"wp:attachment":[{"href":"https:\/\/www.newsbeep.com\/ca\/wp-json\/wp\/v2\/media?parent=554118"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.newsbeep.com\/ca\/wp-json\/wp\/v2\/categories?post=554118"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.newsbeep.com\/ca\/wp-json\/wp\/v2\/tags?post=554118"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}