Heart failure is common in people who have atrial fibrillation detected during screening, according to a presentation today at\u00a0EHRA 2026\u00a0\u00a0the annual congress of the\u00a0European Heart Rhythm Association (EHRA), a branch of the\u00a0European Society of Cardiology (ESC).\u00a0<\/p>\n
Atrial fibrillation (AF) affects almost 38 million people worldwide, with the prevalence predicted to double over the next 35 years.\u00a0Stroke is a feared outcome of AF, but heart failure (HF) also occurs\u00a0frequently\u00a0in patients with AF and is a major cause of death.<\/p>\n
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HF and AF have a bidirectional relationship and accelerate each other’s\u00a0progression , so it is important to\u00a0identify and treat HF early in patients with AF. HF has been well studied in patients with clinically known AF, but little is known about the incidence and timing of HF in individuals whose AF has been detected during screening.”<\/p>\n
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Doctor Gina Sado\u00a0from\u00a0Danderyd\u00a0Hospital, Stockholm, Sweden\u00a0<\/p>\n
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In the Swedish STROKESTOP and STROKESTOP II studies,\u00a0individuals aged 75\u201376 years were randomised to receive ECG-based AF screening or to serve as controls.\u00a0This post-hoc analysis studied the incidence of new HF diagnosis<\/a> based on a median follow-up of 6.9 years for STROKESTOP and 5.1 years for STROKESTOP II. Data on HF diagnoses and mortality were obtained from national registries. Cox regression was used to estimate the hazard ratios (HRs) for incident HF across groups.\u00a0<\/p>\n Out of 6,824 individuals screened in STROKESTOP, new AF was detected in 252 individuals and of these, 57 were diagnosed with HF (23%) over the follow-up period.\u00a0<\/p>\n Out of 6,601 individuals screened in STROKESTOP II, new AF was detected in 152 individuals and of these, 31 were diagnosed with HF (20%) over the follow-up period.\u00a0<\/p>\n In STROKESTOP,\u00a0screening-detected AF was associated with a threefold increased risk of\u00a0HF\u00a0compared with individuals without AF (adjusted HR 3.19; 95% confidence intervals [CI] 2.42 to\u00a04.21) and with a comparable HF risk to patients with previously known AF (adjusted HR 2.86; 95% CI 2.34 to 3.50).\u00a0Similar results\u00a0were\u00a0observed\u00a0in STROKESTOP II.\u00a0<\/p>\n Notably, HF was diagnosed early, within 6 months after AF detection in both studies and AF groups.\u00a0<\/p>\n Summing up the results, Doctor Sado concluded: “In individuals with screening-detected AF, the risk of developing HF was threefold that of participants without AF and comparable to that of patients with clinically known AF. These findings suggest that asymptomatic AF is not a benign condition and highlight the need for early detection of both AF and HF.”\u00a0<\/p>\n Source:<\/p>\n