{"id":709628,"date":"2026-06-02T08:23:16","date_gmt":"2026-06-02T08:23:16","guid":{"rendered":"https:\/\/www.newsbeep.com\/ca\/709628\/"},"modified":"2026-06-02T08:23:16","modified_gmt":"2026-06-02T08:23:16","slug":"ive-donated-part-of-my-brain-to-help-find-a-cure-for-dementia","status":"publish","type":"post","link":"https:\/\/www.newsbeep.com\/ca\/709628\/","title":{"rendered":"I&#8217;ve donated part of my brain to help find a cure for dementia"},"content":{"rendered":"<p><img alt=\"A man and his son smiling at the camera\" loading=\"lazy\" width=\"481\" height=\"271\" decoding=\"async\" data-nimg=\"1\" class=\"rounded-lg\" style=\"color:transparent\" src=\"https:\/\/www.newsbeep.com\/ca\/wp-content\/uploads\/2026\/06\/bb74ce6fd34504c61c533debf5e0bb38.jpeg\"\/><\/p>\n<p>Aidan&#8217;s grandfather died from dementia in 2020 [Aidan McAllister]<\/p>\n<p class=\"mb-4 text-lg md:leading-8 break-words\">A man with a terminal cancer diagnosis has donated part of his brain to researchers working to cure dementia, after watching his grandfather &#8220;disappear&#8221; as a result of the disease.<\/p>\n<p class=\"mb-4 text-lg md:leading-8 break-words\">Aidan McAllister, from Buckhaven in Fife, was told last year that his life would be cut short by a brain tumour.<\/p>\n<p class=\"mb-4 text-lg md:leading-8 break-words\">But when the 28-year-old learned he would need surgery to remove the growth, he gave permission for doctors to take part of his healthy brain matter to use for dementia research.<\/p>\n<p class=\"mb-4 text-lg md:leading-8 break-words\">It was used in a programme which involves keeping living human brain tissue alive for study in the laboratory.<\/p>\n<p class=\"mb-4 text-lg md:leading-8 break-words\">It has been spearheaded by neurosurgeon Paul Brennan, of NHS Lothian&#8217;s department of clinical neurosciences, and Race Against Dementia Fellow Dr Claire Durrant of the University of Edinburgh.<\/p>\n<p class=\"mb-4 text-lg md:leading-8 break-words\">Aidan told <a href=\"https:\/\/www.bbc.co.uk\/sounds\/play\/m002x3yq?xtor=AL-72-%5Bpartner%5D-%5Byahoo.north.america%5D-%5Blink%5D-%5Bnews%5D-%5Bbizdev%5D-%5Bisapi%5D\" rel=\"nofollow noopener\" target=\"_blank\" data-ylk=\"elm:link;elmt:article_link;slk:BBC Radio Scotland Breakfast;itc:0;sec:content-canvas\" data-yga=\"{&quot;yLinkElement&quot;:&quot;context_link&quot;,&quot;yModuleName&quot;:&quot;content-canvas&quot;,&quot;yLinkText&quot;:&quot;BBC Radio Scotland Breakfast&quot;}\" class=\"link \">BBC Radio Scotland Breakfast<\/a> that it was a &#8220;really easy decision&#8221; to agree to donate part of his brain matter.<\/p>\n<p class=\"mb-4 text-lg md:leading-8 break-words\">&#8220;I was getting the craniotomy anyway so they could get the tumour, and to get to the tumour they have to drill a hole,&#8221; he said.<\/p>\n<p class=\"mb-4 text-lg md:leading-8 break-words\">&#8220;They also have to go through healthy brain tissue to get there so they will just take it while they are accessing the tumour.<\/p>\n<p class=\"mb-4 text-lg md:leading-8 break-words\">&#8220;I think they just took about half the size of my pinky and it hasn&#8217;t impacted me at all.&#8221;<\/p>\n<p class=\"mb-4 text-lg md:leading-8 break-words\">Since having surgery to remove as much of the tumour as possible, he has undergone chemotherapy and radiotherapy.<\/p>\n<p><img alt=\"A man wearing a purple hospital gown sits next to a bed\" loading=\"lazy\" width=\"481\" height=\"270\" decoding=\"async\" data-nimg=\"1\" class=\"rounded-lg\" style=\"color:transparent\" src=\"https:\/\/www.newsbeep.com\/ca\/wp-content\/uploads\/2026\/06\/39bf2ce5cd2e79140558e675b16ae853.jpeg\"\/><\/p>\n<p>Aidan is now undergoing chemotherapy [Aidan McAllister]<\/p>\n<p class=\"mb-4 text-lg md:leading-8 break-words\">Contributing to research felt personal for the healthcare worker after his grandfather died from dementia in 2020.<\/p>\n<p class=\"mb-4 text-lg md:leading-8 break-words\">&#8220;My grandad, Thomas, was a big strong man.&#8221; Aidan said. &#8220;He was a miner and to watch him disappear because of the disease was quite hard.<\/p>\n<p class=\"mb-4 text-lg md:leading-8 break-words\">&#8220;We were really close \u2013 he lived just across the road and we saw each other every day.<\/p>\n<p class=\"mb-4 text-lg md:leading-8 break-words\">&#8220;His dementia became so severe that he didn&#8217;t know who he was or who we were.<\/p>\n<p class=\"mb-4 text-lg md:leading-8 break-words\">&#8220;It&#8217;s a really brutal disease.&#8221;<\/p>\n<p>&#8216;Healthy brain tissue&#8217;<\/p>\n<p class=\"mb-4 text-lg md:leading-8 break-words\">The pioneering research Aidan donated his brain matter to has allowed scientists to show how a toxic form of a protein linked to Alzheimer&#8217;s can attach to and damage the connections between brain cells.<\/p>\n<p class=\"mb-4 text-lg md:leading-8 break-words\">The researchers hope the discovery will help identify medication that can prevent the loss of synapses &#8211; the vital connections that allow messages to flow between brain cells and support healthy brain function.<\/p>\n<p class=\"mb-4 text-lg md:leading-8 break-words\">Neurosurgeon Paul Brennan said: &#8220;During neurosurgery, there is always a small amount of healthy brain tissue that must be removed in order to reach, for example, a tumour and typically that tissue would be thrown away.<\/p>\n<p class=\"mb-4 text-lg md:leading-8 break-words\">&#8220;Our partnership with Claire and her team means we can package up that healthy, living tissue and send it to the lab for testing.<\/p>\n<p class=\"mb-4 text-lg md:leading-8 break-words\">&#8220;Even the tiniest piece contains thousands of cells, and we can learn a great deal from it.<\/p>\n<p class=\"mb-4 text-lg md:leading-8 break-words\">&#8220;Research of this type has been underway for some time, but this collaboration allows us to study living human brain tissue in a way that hasn&#8217;t routinely been possible before.&#8221;<\/p>\n","protected":false},"excerpt":{"rendered":"Aidan&#8217;s grandfather died from dementia in 2020 [Aidan McAllister] A man with a terminal cancer diagnosis has donated&hellip;\n","protected":false},"author":2,"featured_media":709629,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[10],"tags":[257712,37650,257711,257710,103389,49,48,10237,84,257714,257713,257709],"class_list":["post-709628","post","type-post","status-publish","format-standard","has-post-thumbnail","category-health","tag-aidan-mcallister","tag-brain-cells","tag-brain-matter","tag-brain-tissue","tag-brain-tumour","tag-ca","tag-canada","tag-dementia","tag-health","tag-healthy-brain","tag-healthy-brain-matter","tag-paul-brennan"],"_links":{"self":[{"href":"https:\/\/www.newsbeep.com\/ca\/wp-json\/wp\/v2\/posts\/709628","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.newsbeep.com\/ca\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.newsbeep.com\/ca\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/ca\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/ca\/wp-json\/wp\/v2\/comments?post=709628"}],"version-history":[{"count":0,"href":"https:\/\/www.newsbeep.com\/ca\/wp-json\/wp\/v2\/posts\/709628\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/ca\/wp-json\/wp\/v2\/media\/709629"}],"wp:attachment":[{"href":"https:\/\/www.newsbeep.com\/ca\/wp-json\/wp\/v2\/media?parent=709628"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.newsbeep.com\/ca\/wp-json\/wp\/v2\/categories?post=709628"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.newsbeep.com\/ca\/wp-json\/wp\/v2\/tags?post=709628"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}