{"id":741480,"date":"2026-06-16T22:57:10","date_gmt":"2026-06-16T22:57:10","guid":{"rendered":"https:\/\/www.newsbeep.com\/ca\/741480\/"},"modified":"2026-06-16T22:57:10","modified_gmt":"2026-06-16T22:57:10","slug":"taking-laxatives-can-help-with-memory-and-attention-span-problems","status":"publish","type":"post","link":"https:\/\/www.newsbeep.com\/ca\/741480\/","title":{"rendered":"Taking laxatives can help with memory and attention span problems"},"content":{"rendered":"<p>Talk about a gut-brain connection.<\/p>\n<p>Scientists have long known about the link between our <a href=\"https:\/\/nypost.com\/2024\/10\/16\/health\/brain-doctor-advises-avoiding-junk-food-if-youre-depressed\/\" rel=\"nofollow noopener\" target=\"_blank\">stomachs and our brains<\/a>, warning that our diets and gut health have a large impact on mood and mental health.<\/p>\n<p>And a study published Monday may have found a way to flush the brain fog and attention issues that accompany depression down the toilet.<\/p>\n<p><img style=\"aspect-ratio:1.49926794;display:block\" loading=\"lazy\" decoding=\"async\" data-modal-image=\"39695072\" width=\"885\" height=\"590\" src=\"https:\/\/www.newsbeep.com\/ca\/wp-content\/uploads\/2026\/06\/diarrhea-concept-treatment-stomach-intestinal-131178084.jpg\" alt=\"Hands holding toilet paper and a pill, symbolizing diarrhea treatment.\" class=\"wp-image-39695072\"  \/>New research has found a potential solution from a laxative for brain fog and attention issues that come with depression. Goffkein \u2013 stock.adobe.com<\/p>\n<p>Cognition issues are common with depression and mental disorders, including trouble with thinking, planning tasks, and both short- and long-term memory.<\/p>\n<p>A team of researchers from the <a href=\"https:\/\/www.cambridge.org\/core\/journals\/psychological-medicine\/article\/procognitive-effects-of-5ht4-receptor-agonism-in-individuals-with-remitted-depression\/EE5A729AD6632A6ED97AC24C8F17DCCB\" target=\"_blank\" rel=\"noopener nofollow\">University of Birmingham and the University of Oxford<\/a> conducted a study looking at the effects of prucalopride, a prescription drug for constipation, on cognitive issues.<\/p>\n<p>Those who took the laxative performed better and faster on cognitive tests to measure focus, attention span, planning, balancing multiple tasks, short- and long-term memory and emotional cognition tasks.<\/p>\n<p>Fifty patients between 18 and 40 with a history of depressive episodes were recruited to take either a two-milligram dose of the laxative \u2014 the amount used for chronic constipation \u2014 or a placebo for seven to 10 days.<\/p>\n<p>Both before and after taking the drug, participants took a variety of tests that included a working memory task, an auditory verbal learning and memory task and a task on attention and processing speed.<\/p>\n<p>Prucalopride works by gently stimulating bowel movements, but it also activates a serotonin receptor in the gut and brain known as the fourth serotonin receptor, or 5HT4.<\/p>\n<p><img style=\"aspect-ratio:1.43417367;display:block\" loading=\"lazy\" decoding=\"async\" data-modal-image=\"39695070\" width=\"846\" height=\"590\" src=\"https:\/\/www.newsbeep.com\/ca\/wp-content\/uploads\/2026\/06\/131178088.jpg\" alt=\"Woman at a desk, looking stressed, surrounded by crumpled colorful papers while working.\" class=\"wp-image-39695070\"  \/>A medication for constipation, prucalopride, also works on a serotonin receptor that affects mood and memory. Nadzeya \u2013 stock.adobe.com<\/p>\n<p>These receptors work both to <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK548948\/\" target=\"_blank\" rel=\"noopener nofollow\">increase gut motility<\/a> and how fast the bowels empty, and are heavily involved with learning, memory, mood and anxiety.<\/p>\n<p>According to researchers, the medication could help an often overlooked effect of depression.<\/p>\n<p>\u201cFor many people, recovery from depression is incomplete because difficulties with memory and concentration persist,\u201d senior author professor Susannah Murphy said in a <a href=\"https:\/\/www.eurekalert.org\/news-releases\/1131831\" target=\"_blank\" rel=\"noopener nofollow\">press release<\/a>.<\/p>\n<p>\u201cThis study provides early evidence that 5HT4 receptor agonists could help restore aspects of cognitive function, opening an exciting new direction for treatment development,\u201d she added.<\/p>\n<p>This study follows <a href=\"https:\/\/www.cambridge.org\/core\/journals\/the-british-journal-of-psychiatry\/article\/association-between-a-selective-5ht4-receptor-agonist-and-incidence-of-major-depressive-disorder-emulated-target-trial\/114C8A388EE58FCC23E03C59C25FAE1D\" target=\"_blank\" rel=\"noopener nofollow\">previous research from 2024<\/a> that also showed 5HT4 receptor agonists used for constipation may also reduce the risk of depression in those with no history of the illness.<\/p>\n<p>Another study found that <a href=\"https:\/\/nypost.com\/2024\/06\/12\/health\/how-depression-as-a-young-adult-can-lead-to-memory-problems\/\" rel=\"nofollow noopener\" target=\"_blank\">experiencing depressive symptoms<\/a> could lead to worsened memory and thinking skills when hitting middle age.<\/p>\n<p>And what we eat can play a role in brain health, especially as we age.<\/p>\n<p>\u201cEvidence suggests that the gut microbiome may influence inflammation, metabolism and brain function through the\u00a0gut-brain axis,\u201d <a href=\"https:\/\/www.northwell.edu\/find-care\/find-a-doctor\/dr-randy-scott-damico-md-1376809582\" target=\"_blank\" rel=\"noreferrer noopener nofollow\">Dr. Randy D\u2019Amico<\/a>, director of the Brain and Spine Metastasis Program of Neurosurgery at Northwell Lenox Hill Hospital, <a href=\"https:\/\/nypost.com\/2026\/06\/10\/health\/neurosurgeon-5-ways-i-keep-my-brain-healthy\/\" rel=\"nofollow noopener\" target=\"_blank\">previously told The Post<\/a>.<\/p>\n","protected":false},"excerpt":{"rendered":"Talk about a gut-brain connection. Scientists have long known about the link between our stomachs and our brains,&hellip;\n","protected":false},"author":2,"featured_media":741481,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[33],"tags":[65342,49,48,6319,7716,84,377,33339,14592],"class_list":["post-741480","post","type-post","status-publish","format-standard","has-post-thumbnail","category-medication","tag-brains","tag-ca","tag-canada","tag-depression","tag-gut-health","tag-health","tag-medication","tag-poop","tag-study-says"],"_links":{"self":[{"href":"https:\/\/www.newsbeep.com\/ca\/wp-json\/wp\/v2\/posts\/741480","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.newsbeep.com\/ca\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.newsbeep.com\/ca\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/ca\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/ca\/wp-json\/wp\/v2\/comments?post=741480"}],"version-history":[{"count":0,"href":"https:\/\/www.newsbeep.com\/ca\/wp-json\/wp\/v2\/posts\/741480\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/ca\/wp-json\/wp\/v2\/media\/741481"}],"wp:attachment":[{"href":"https:\/\/www.newsbeep.com\/ca\/wp-json\/wp\/v2\/media?parent=741480"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.newsbeep.com\/ca\/wp-json\/wp\/v2\/categories?post=741480"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.newsbeep.com\/ca\/wp-json\/wp\/v2\/tags?post=741480"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}