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Finerenone, also known as Kerendia, slows kidney function decline and reduces the risk of serious kidney and cardiovascular complications in people with chronic kidney disease (CKD). The corresponding study was published in the New England Journal of Medicine<\/a>.<\/p>\n \u200b”Finerenone could become an important new treatment option for people with chronic kidney disease who do not have diabetes. The drug offers a clear delay in the decline of kidney function on top of current standard care,\u201d said lead author of the study, Hiddo Lambers Heerspink, \u00a0clinical pharmacologist at the University Medical Center Groningen, in a press release<\/a>.<\/p>\n \u200bFor the study, researchers recruited 1584 patients without diabetes who had CKD. They were split into two groups: one taking finerenone and the other a placebo. The researchers examined how kidney function changed over a 2.5-year follow-up via estimated glomerular filtration rate (eGFR), which reflects how effectively kidneys filter waste from the blood.<\/p>\n \u200bUltimately, those taking finerenone experienced a statistically significant slower decline of eGFR compared to those receiving the placebo. The drug also reduced the likelihood of serious health complications such as major kidney events, hospitalization for heart failure, and death from cardiovascular disease.<\/p>\n \u200bLambers Heerspink noted that the drug additionally led to a significant reduction in urinary protein, which is an early indicator of kidney damage. Those taking finerenone saw levels of this protein decrease by an average of 41% compared to around 9% in the placebo group. Such reductions are an important indicator of a more favorable renal prognosis, said Lambers Heerspink.<\/p>\n \u200b\u201cThe results provide physicians with new therapeutic options to help preserve kidney function and reduce the number of cardiovascular and renal complications. And this applies to a broad, underserved patient population with non-diabetic CKD, for whom there are few treatment options in the guidelines,\u201d said Lambers Heerspink.<\/p>\n \u200b<\/p>\n Sources: Science Daily<\/a>, New England Journal of Medicine<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"\u00a0 Finerenone, also known as Kerendia, slows kidney function decline and reduces the risk of serious kidney and…\n","protected":false},"author":2,"featured_media":818524,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[10],"tags":[49,48,84],"class_list":["post-818523","post","type-post","status-publish","format-standard","has-post-thumbnail","category-health","tag-ca","tag-canada","tag-health"],"_links":{"self":[{"href":"https:\/\/www.newsbeep.com\/ca\/wp-json\/wp\/v2\/posts\/818523","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.newsbeep.com\/ca\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.newsbeep.com\/ca\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/ca\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/ca\/wp-json\/wp\/v2\/comments?post=818523"}],"version-history":[{"count":0,"href":"https:\/\/www.newsbeep.com\/ca\/wp-json\/wp\/v2\/posts\/818523\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/ca\/wp-json\/wp\/v2\/media\/818524"}],"wp:attachment":[{"href":"https:\/\/www.newsbeep.com\/ca\/wp-json\/wp\/v2\/media?parent=818523"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.newsbeep.com\/ca\/wp-json\/wp\/v2\/categories?post=818523"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.newsbeep.com\/ca\/wp-json\/wp\/v2\/tags?post=818523"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}