{"id":905477,"date":"2026-09-22T15:34:09","date_gmt":"2026-09-22T15:34:09","guid":{"rendered":"https:\/\/www.newsbeep.com\/ca\/905477\/"},"modified":"2026-09-22T15:34:09","modified_gmt":"2026-09-22T15:34:09","slug":"new-study-characterizes-clinically-tremulous-movements-in-cidp","status":"publish","type":"post","link":"https:\/\/www.newsbeep.com\/ca\/905477\/","title":{"rendered":"New Study Characterizes Clinically Tremulous Movements in CIDP"},"content":{"rendered":"

In a cross-sectional study published in the\u00a0Journal of Neurology, Neurosurgery & Psychiatry<\/a>, Gabri\u00eblle Pallada, a PhD candidate at the University of Amsterdam in the Netherlands, and colleagues, evaluated the prevalence, clinical characteristics, and treatment response of tremor in patients with CIDP (n=124).<\/p>\n

Tremor was assessed using the Fahn-Tolosa-Marin Clinical Rating Scale for Tremor (FTM-TRS) and electromyography tremor recording. The authors also used validated scales and questionnaires to assess CIDP and additional tremor characteristics.<\/p>\n

Results showed that 69% of patients (n=86) currently had clinically tremulous movements (CTMs). Most of these were tremor, but some involved myoclonus or both. Lifetime prevalence was 76%.<\/p>\n

CTMs were present in the upper extremities of all patients (median FTM-TRS part A [FTM-TRS-A] upper extremity score, 4; range, 1-16) and in the lower extremities of 20% (median FTM-TRS-A lower extremity score, 0; range, 0-9). Both tremor and myoclonus were most prevalent during action\/intention, and CTMs were associated with both CIDP-related and tremor-related disability.<\/p>\n

Patients with CTMs had significantly higher upper extremity disability scores as measured by the Inflammatory Neuropathy Cause and Treatment scale (INCAT-DS-UE) compared with patients without CTMs (2 points and 1 point, respectively;\u00a0P=0.03).<\/p>\n

Immune therapy, which targets the underlying neuropathy, led to complete or partial improvement of CTMs in 46% of those who received CIDP treatment on tremor (n=22). In comparison, 80% of those who were treated with a beta-blocker reported partial improvement (n=8).<\/p>\n

Overall, these findings indicate that CTMs are common in patients with CIDP, and although CTMs are typically mild, they contribute to disability in many patients. The authors note that the findings could lead to improved awareness of tremor among clinicians treating patients with CIDP, along with advances in treatment and patient education.<\/p>\n","protected":false},"excerpt":{"rendered":"In a cross-sectional study published in the\u00a0Journal of Neurology, Neurosurgery & Psychiatry, Gabri\u00eblle Pallada, a PhD candidate at…\n","protected":false},"author":2,"featured_media":905478,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[10],"tags":[49,48,84],"class_list":["post-905477","post","type-post","status-publish","format-standard","has-post-thumbnail","category-health","tag-ca","tag-canada","tag-health"],"_links":{"self":[{"href":"https:\/\/www.newsbeep.com\/ca\/wp-json\/wp\/v2\/posts\/905477","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.newsbeep.com\/ca\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.newsbeep.com\/ca\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/ca\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/ca\/wp-json\/wp\/v2\/comments?post=905477"}],"version-history":[{"count":0,"href":"https:\/\/www.newsbeep.com\/ca\/wp-json\/wp\/v2\/posts\/905477\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/ca\/wp-json\/wp\/v2\/media\/905478"}],"wp:attachment":[{"href":"https:\/\/www.newsbeep.com\/ca\/wp-json\/wp\/v2\/media?parent=905477"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.newsbeep.com\/ca\/wp-json\/wp\/v2\/categories?post=905477"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.newsbeep.com\/ca\/wp-json\/wp\/v2\/tags?post=905477"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}