{"id":929766,"date":"2026-10-12T03:39:18","date_gmt":"2026-10-12T03:39:18","guid":{"rendered":"https:\/\/www.newsbeep.com\/ca\/929766\/"},"modified":"2026-10-12T03:39:18","modified_gmt":"2026-10-12T03:39:18","slug":"cycling-cryotherapy-topicals-and-pdt-for-actinic-keratosis-management","status":"publish","type":"post","link":"https:\/\/www.newsbeep.com\/ca\/929766\/","title":{"rendered":"Cycling Cryotherapy, Topicals, and PDT for Actinic Keratosis Management"},"content":{"rendered":"<p> Independent Study of Actinic Keratosis Cycle Therapy<\/p>\n<p class=\"\">Bhatia is running an independent study of freezing, topicals, and PDT. Patients have 4 to 12 actinic keratoses on the face or scalp and receive cryotherapy at the first visit. They are then randomized to 5 days of tirbanibulin ointment followed by 2 cycles of blue light PDT.<\/p>\n<p class=\"\">He is assessing lesion counts at the end of treatment, cosmetic indices, clearance, and tolerability. Bhatia said all patients so far are doing really well on therapy.<\/p>\n<p class=\"\">\u201cFreezing and being done is not the only answer,\u201d Bhatia said.<\/p>\n<p>Red Light PDT for Superficial Basal Cell Carcinoma<\/p>\n<p class=\"\">Bhatia described the latest <a href=\"https:\/\/www.dermatologytimes.com\/view\/fda-approves-ameluz-red-light-pdt-for-superficial-basal-cell-carcinoma\" target=\"_blank\" rel=\"nofollow noopener\">approval of aminolevulinic acid (ALA) 10% with red light for superficial basal cell carcinoma<\/a>. Previous options focused more on squamous cell carcinoma in situ, for which both red and blue light are available. Blue light is also available for actinic keratosis.<\/p>\n<p class=\"\">He named the pretibial surfaces, behind the ears, and around the eyes as areas where surgery may be more difficult and red light PDT may fit. Superficial basal cell carcinomas also arise on the chest, face, legs, and extremities. Red light PDT can shrink the tumor or serve as monotherapy.<\/p>\n<p class=\"\">\u201cThis is a good option for patients who may not be surgical candidates,\u201d Bhatia said.<\/p>\n<p>Avoiding Pitfalls in Clinical Research<\/p>\n<p class=\"\">Bhatia also gave a lecture in the Mentoring for Leadership session on avoiding mistakes when incorporating clinical trials into practice. He said a busy clinic does not always translate into a busy research center, and overlooked nuances can affect enrollment and regulatory requirements. Some attendees told him the lecture scared them straight, but he encouraged them not to be discouraged.<\/p>\n<p class=\"\">\u201cIt\u2019s about just being accurate, being prompt, and being set up for success in a research trial unit,\u201d Bhatia said.<\/p>\n<p class=\"\">He advised starting with case reports or an independent phase 4 study, then moving to lighter phase 3 trials, with phase 1 and phase 2 work as a golden opportunity for dermatologists. \u201cJust start slowly, like we all do, and learn from our mistakes,\u201d he said.<\/p>\n","protected":false},"excerpt":{"rendered":"Independent Study of Actinic Keratosis Cycle Therapy Bhatia is running an independent study of freezing, topicals, and PDT.&hellip;\n","protected":false},"author":2,"featured_media":929767,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[445],"tags":[49,48,635,82],"class_list":["post-929766","post","type-post","status-publish","format-standard","has-post-thumbnail","category-cycling","tag-ca","tag-canada","tag-cycling","tag-sports"],"_links":{"self":[{"href":"https:\/\/www.newsbeep.com\/ca\/wp-json\/wp\/v2\/posts\/929766","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.newsbeep.com\/ca\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.newsbeep.com\/ca\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/ca\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/ca\/wp-json\/wp\/v2\/comments?post=929766"}],"version-history":[{"count":0,"href":"https:\/\/www.newsbeep.com\/ca\/wp-json\/wp\/v2\/posts\/929766\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/ca\/wp-json\/wp\/v2\/media\/929767"}],"wp:attachment":[{"href":"https:\/\/www.newsbeep.com\/ca\/wp-json\/wp\/v2\/media?parent=929766"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.newsbeep.com\/ca\/wp-json\/wp\/v2\/categories?post=929766"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.newsbeep.com\/ca\/wp-json\/wp\/v2\/tags?post=929766"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}