{"id":929898,"date":"2026-10-12T06:04:18","date_gmt":"2026-10-12T06:04:18","guid":{"rendered":"https:\/\/www.newsbeep.com\/ca\/929898\/"},"modified":"2026-10-12T06:04:18","modified_gmt":"2026-10-12T06:04:18","slug":"ultra-processed-vs-whole-foods-whats-the-metabolic-impact","status":"publish","type":"post","link":"https:\/\/www.newsbeep.com\/ca\/929898\/","title":{"rendered":"Ultra-processed vs whole foods: What&#8217;s the metabolic impact?"},"content":{"rendered":"<p><img decoding=\"async\" loading=\"eager\" src=\"https:\/\/www.newsbeep.com\/ca\/wp-content\/uploads\/2026\/10\/getty_1490835150_header_1296x728-1024x575.jpg\" alt=\"two subs and a pack of fries on a tray\" class=\"css-bt1qz0\"\/><a class=\"icon-hl-pinterest css-o1zxgm\" target=\"_blank\" rel=\"noopener noreferrer nofollow\" data-event=\"Any Page|Image Pinterest Click|Icon Clicked\" data-element-event=\"OPEN|CONTENTBLOCK|Any Page|Article Body|BUTTON|Image Widget Pinterest Click|\" href=\"https:\/\/www.pinterest.com\/pin\/create\/button\/?url=https%3A%2F%2Fwww.medicalnewstoday.com%2Farticles%2Feven-when-nutrient-dense-ultra-processed-foods-alter-insulin-response&amp;media=https%3A%2F%2Fmedia.post.rvohealth.io%2Fwp-content%2Fuploads%2Fsites%2F3%2F2026%2F10%2Fgetty_1490835150_header_1296x728-1024x575.jpg&amp;description=Ultra-processed%20vs%20whole%20foods%3A%20What&#039;s%20the%20metabolic%20impact%3F\" title=\"Share on Pinterest\" data-pin-custom=\"true\" data-share-url=\"https:\/\/www.newsbeep.com\/ca\/wp-content\/uploads\/2026\/10\/getty_1490835150_header_1296x728-1024x575.jpg\">Share on Pinterest<\/a>Ultra-processed foods may alter insulin responses differently compared to less processed foods with similar nutrients, a new study has found. AzmanL\/ Getty ImagesA new study compared how adults responded to ultra-processed and less processed meals with similar nutrients.The ultra-processed meal led to a higher insulin response and changed how the body used energy.The team also examined the participants\u2019 brain activity while they viewed pictures of ultra-processed and less processed foods.<\/p>\n<p>Nutrition labels can help people choose foods that meet their calorie or protein needs, but those numbers may not tell the whole story about how the body will respond after eating.<\/p>\n<p>Researchers at Virginia Tech recently explored whether food processing affects the body\u2019s response independently of nutrient content.<\/p>\n<p>They compared the body\u2019s responses to two meals that were similar in nutrient makeup but differed in <a href=\"https:\/\/www.medicalnewstoday.com\/articles\/318630\" class=\"content-link css-1h9c35y\" rel=\"nofollow noopener\" target=\"_blank\">processing level<\/a>. They also examined brain activity to explore whether metabolic differences related to participants\u2019 responses to food pictures.<\/p>\n<p><a href=\"https:\/\/healthyeatingresearch.org\/wp-content\/uploads\/2026\/05\/HER-UPF-Expert-Panel-Technical-Report-04-1.pdf\" target=\"_blank\" rel=\"noopener noreferrer nofollow\" class=\"content-link css-1h9c35y\">Ultra-processed foods<\/a> often have ingredients that improve flavor, texture, or shelf life. The <a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC10261019\/\" target=\"_blank\" rel=\"noopener noreferrer nofollow\" class=\"content-link css-1h9c35y\">NOVA classification system<\/a> groups foods by their level of processing. For example, plain nuts and eggs belong to group 1, while soda and many packaged chips belong to group 4.<\/p>\n<p>Since ultra-processed foods can provide nutrients such as <a href=\"https:\/\/www.medicalnewstoday.com\/articles\/196279\" class=\"content-link css-1h9c35y\" rel=\"nofollow noopener\" target=\"_blank\">protein<\/a> and <a href=\"https:\/\/www.medicalnewstoday.com\/articles\/146935\" class=\"content-link css-1h9c35y\" rel=\"nofollow noopener\" target=\"_blank\">fiber<\/a>, processing level alone does not describe a food\u2019s nutritional profile. To better understand whether processing matters beyond those nutrients, the researchers compared nutritionally matched meals.<\/p>\n<p>The study included 57 healthy-weight adults aged 18 to 45. Of these, 32 completed both meal-testing sessions, and the researchers included 52 in their brain imaging analysis.<\/p>\n<p>After participants fasted overnight, the team collected baseline measurements and served a meal of around 300 calories. Each of the 32 participants ate both meal types on separate days, and the researchers randomized the order.<\/p>\n<p>Some of the foods the researchers served in the non-ultra-processed session included banana slices and cheese. For the ultra-processed meal, some foods included a portion of a peanut butter and jelly sandwich and veggie chips.<\/p>\n<p>After the participants finished eating, the researchers collected blood samples multiple times over the following three hours.<\/p>\n<p>During another visit, participants bid on pictured foods while researchers monitored their brain activity with <a href=\"https:\/\/www.medicalnewstoday.com\/articles\/146309\" class=\"content-link css-1h9c35y\" rel=\"nofollow noopener\" target=\"_blank\">functional MRI<\/a>. The researchers used the bids to estimate how much participants valued each item.<\/p>\n<p>The researchers tracked blood sugar, insulin, and energy use after each meal.<\/p>\n<p>Despite similar overall blood sugar responses, the participants had a greater insulin response after the ultra-processed meal. Their insulin levels stayed higher between 40 and 120 minutes after eating.<\/p>\n<p>The higher insulin response made the researchers wonder whether ultra-processed foods place greater demands on how the body regulates <a href=\"https:\/\/www.medicalnewstoday.com\/articles\/317536\" class=\"content-link css-1h9c35y\" rel=\"nofollow noopener\" target=\"_blank\">blood sugar<\/a>. However, the study did not establish that this response was harmful or indicated insulin resistance.<\/p>\n<p>Participants also burned fewer carbohydrates and more fat while expending more energy after eating their ultra-processed meals.<\/p>\n<p>The researchers also linked differences in carbohydrate burning after the meals to differences in brain responses to food pictures during the MRI visit. The participants bid similar amounts for both food categories, but the findings suggested that <a href=\"https:\/\/www.medicalnewstoday.com\/articles\/metabolic-disorders\" class=\"content-link css-1h9c35y\" rel=\"nofollow noopener\" target=\"_blank\">metabolic<\/a> responses may relate to how the brain processes food cues.<\/p>\n<p>Overall, the findings suggest that nutrient content alone may not fully explain the body\u2019s response to food. Processing may also matter.<\/p>\n<p>However, the study tested only one pair of small meals in relatively young, healthy-weight adults. The researchers need to conduct larger, longer studies to determine whether these differences persist and affect health over time.<\/p>\n<p><a href=\"https:\/\/www.memorialcare.org\/providers\/mir-b-ali\" target=\"_blank\" rel=\"noopener noreferrer nofollow\" class=\"content-link css-1h9c35y\">Mir Ali<\/a>, MD, a bariatric surgeon and medical director of MemorialCare Surgical Weight Loss Center at Orange Coast Medical Center, who was not involves in the study, discussed the findings with Medical News Today.<\/p>\n<p>\u201cThis study showed that ultra-processed foods (UPFs) have a significant hormonal and metabolic effect on the body, altering insulin response and carbohydrate metabolism,\u201d said Ali.<\/p>\n<p>However, he emphasized that the researchers still need to identify which aspects of these foods drive the differences.<\/p>\n<p>\u201cThe study did not differentiate between processing methods and extra ingredients in [ultra-processed foods],\u201d Ali noted. \u201cFurther research is needed to determine the most harmful aspects of ultra-processed foods.\u201d<\/p>\n<p>For everyday food choices, Ali recommended limiting <a href=\"https:\/\/www.medicalnewstoday.com\/articles\/every-extra-100-grams-of-ultra-processed-foods-tied-to-greater-disease-risk\" class=\"content-link css-1h9c35y\" rel=\"nofollow noopener\" target=\"_blank\">ultra-processed foods<\/a> while acknowledging the challenges people face.<\/p>\n<p>\u201cI advise my patients to minimize UPFs, though they remain difficult to avoid because they are inexpensive, accessible, and highly palatable,\u201d shared Ali.<\/p>\n<p><a href=\"https:\/\/www.drnutritionchanger.com\/services-1\" target=\"_blank\" rel=\"noopener noreferrer nofollow\" class=\"content-link css-1h9c35y\">Qianzhi Jiang<\/a>, PhD, RD, a pediatric and family dietitian with The Nutrition Changer, also discussed the study findings with MNT.<\/p>\n<p>\u201cIt adds to growing evidence that what happens to food during processing may matter beyond what we see on a nutrition label,\u201d shared Jiang, who likewise was not involved in the study.<\/p>\n<p>Jiang explained that <a href=\"https:\/\/www.medicalnewstoday.com\/articles\/carbs-fat-protein-which-one-triggers-more-insulin-release\" class=\"content-link css-1h9c35y\" rel=\"nofollow noopener\" target=\"_blank\">insulin release<\/a> responds to protein and amino acids and that the differences in ingredients and protein sources could have contributed to the findings.<\/p>\n<p>\u201cWe should be cautious about interpreting the higher insulin response as evidence of a more severe problem,\u201d she said.<\/p>\n<p>Jiang pointed out that the study did not examine whether hormones, such as <a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC4020673\/\" target=\"_blank\" rel=\"noopener noreferrer nofollow\" class=\"content-link css-1h9c35y\">GIP and GLP-1<\/a>, contributed to the higher insulin response. <\/p>\n<p>She also noted that the NOVA system was not originally intended to be \u201ca measure of nutritional quality or overall healthfulness\u201d and that it would be interesting to see how the foods scored on the <a href=\"https:\/\/www.fna.usda.gov\/cnpp\/healthy-eating-index\" target=\"_blank\" rel=\"noopener noreferrer nofollow\" class=\"content-link css-1h9c35y\">Healthy Eating Index<\/a>.<\/p>\n","protected":false},"excerpt":{"rendered":"Share on PinterestUltra-processed foods may alter insulin responses differently compared to less processed foods with similar nutrients, a&hellip;\n","protected":false},"author":2,"featured_media":929899,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[36],"tags":[49,48,84,16956,395],"class_list":["post-929898","post","type-post","status-publish","format-standard","has-post-thumbnail","category-nutrition","tag-ca","tag-canada","tag-health","tag-metabolism","tag-nutrition"],"_links":{"self":[{"href":"https:\/\/www.newsbeep.com\/ca\/wp-json\/wp\/v2\/posts\/929898","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.newsbeep.com\/ca\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.newsbeep.com\/ca\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/ca\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/ca\/wp-json\/wp\/v2\/comments?post=929898"}],"version-history":[{"count":0,"href":"https:\/\/www.newsbeep.com\/ca\/wp-json\/wp\/v2\/posts\/929898\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/ca\/wp-json\/wp\/v2\/media\/929899"}],"wp:attachment":[{"href":"https:\/\/www.newsbeep.com\/ca\/wp-json\/wp\/v2\/media?parent=929898"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.newsbeep.com\/ca\/wp-json\/wp\/v2\/categories?post=929898"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.newsbeep.com\/ca\/wp-json\/wp\/v2\/tags?post=929898"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}