Stocking up on seasonal fall foods is an easy, affordable and nutritious way to reduce inflammation.Excellent options include pumpkin, kale, mushrooms, pears, walnuts and cranberries for their anti-inflammatory properties.For the most benefits, eat plenty of colorful foods and choose whole foods most often.

Inflammation seems to be the health buzzword of the year, and it’s finally getting the attention it deserves. While some inflammation is normal—like your body responding to a cut or brief illness—chronic, low grade inflammation can quietly take a toll on your body and contribute to a range of health issues.

The good news? Your diet can help. Prioritizing anti-inflammatory foods—especially colorful, seasonal produce—is a delicious and cost-effective way to support your health.

Now that November’s here, it’s time to transition into some cozy, nutrient-packed meals that fight inflammation. Buying in-season foods not only saves money but also ensures you get peak nutrition. 

To help, we rounded up 8 anti-inflammatory options that are at their best in November. Add these picks to your cart and enjoy nourishing meals all season long.

1. Pumpkin

Pumpkin isn’t just for pie. Its vibrant orange color signals a rich supply of carotenoids like beta-carotene—an antioxidant that helps protect cells from oxidative stress and calm inflammation—along with lutein and zeaxanthin, which support eye health. Pumpkin also provides vitamin C, vitamin E, potassium and fiber, which support immunity and help keep inflammation in check. 

“The antioxidants found in pumpkin protect the body against chronic disease by neutralizing the effects of free radicals and cellular damage,” says Madeline Schneider, RDN, LDN.

Beyond pies, try roasting pumpkin to bring out its natural sweetness or stirring canned purée into oatmeal or soup. Don’t toss the seeds—toast them for a crunchy topping that adds healthy fats and extra antioxidants to salads, yogurt or trail mix.

Not a fan of pumpkin? Other seasonal squash and root vegetables provide similar benefits, like acorn or butternut squash, sweet potatoes, yams and carrots.

2. Pears

Move over, apples—sweet, juicy pears deserve more love, especially if you’re eating to fight inflammation. “Pears contain chlorogenic acid, a polyphenol that has been studied for its antioxidant and anti-inflammatory benefits. Most of those nutrients are found in the skin, so keep the peel on when possible.” says Katharine Rosenthal, RDN, LDN.

In addition to chlorogenic acid, pears supply flavonoids, triterpenoids, phenolic acids and fiber—a combination that has been linked to reduced inflammatory markers and improved metabolic health.

“Pears prove that nutrition isn’t about one magic nutrient,” Rosenthal adds. “It’s about the synergy of many micronutrients working together for your health.” Enjoy pears sliced with nut butter, roasted with cinnamon or chopped into fall salads.

3. Mushrooms 

Mushrooms deliver beta-glucans, a special type of fiber that helps regulate the body’s immune response and calm inflammation. They also provide antioxidants like ergothioneine and phenolic compounds, which help combat oxidative stress linked to chronic inflammation.

Whether you sauté them for pasta, roast them for a cozy side or add them to soups and stews, mushrooms offer an easy, delicious way to work more anti-inflammatory nutrients into fall meals.

4. Kale 

Kale thrives in cool weather, making it a perfect fall favorite. “Kale is packed with nutrients and phytochemicals that provide health-protective effects,” says Schneider. This leafy green is rich in glucosinolates and flavonoids, which are plant compounds that help lower inflammatory markers and protect against oxidative stress. Diets high in these compounds are linked to a lower risk of chronic conditions, such as heart disease, diabetes and certain cancers. 

Not sure how to use kale? Massage kale with olive oil for salads, bake it into crispy chips or stir chopped leaves into soups and stews for extra fiber and phytonutrients. 

Other seasonal options with similar benefits include Brussels sprouts, broccoli, cabbage and bok choy.

5. Ginger 

Ginger contains hundreds of natural bioactive compounds, with gingerols and shogaols being the most abundant. These plant compounds protect cells from oxidative stress, helping to reduce chronic inflammation. While often associated with soothing an upset stomach, early research suggests that regularly enjoying ginger may help ease muscle soreness, joint discomfort and other low-grade inflammation.

It’s also incredibly versatile: grate fresh ginger into stir-fries or soups, blend it into smoothies or steep slices in hot water for a cozy, warming tea.

6. Cranberries 

Yes, they’re great for cranberry sauce, but cranberries are more than just a sweet addition to turkey. They’re packed with anti-inflammatory plant compounds, including polyphenols like proanthocyanidins and flavonols, as well as vitamins C and E. Research suggests these nutrients have antioxidant and anti-inflammatory effects and may help support heart health, protect against urinary tract infections, reduce blood pressure and even combat harmful bacteria such as Helicobacter pylori.

Much of the nutritional benefits come from the cranberry skin, so whole cranberries—fresh or frozen—deliver more nutrients than sweetened juices. Toss them into baked oatmeal, roast them with a drizzle of maple syrup or simmer a homemade cranberry sauce that keeps added sugar in check.

7. Walnuts 

Fun fact: walnuts are harvested from mid-September to early November. They pack a powerful combination of omega-3 fats, vitamin E, prebiotic fiber and antioxidant polyphenols that work together to calm inflammation and support long-term health.

One of their key compounds, called ellagitannins, is transformed by gut bacteria into beneficial molecules—such as short-chain fatty acids—that help protect cells and may reduce chronic inflammation.

“Every handful of walnuts provides a mix of beneficial nutrients that work together to support long-term health,” says Rosenthal. Research suggests these nutrients promote heart and gut health, with growing evidence linking regular walnut intake to lower disease risk.

Adding a small handful to oatmeal, salads or roasted vegetables to easily boost nutrition and flavor every day.

8. Salmon

With November marking the tail end of salmon season, now is a great time to enjoy fresh salmon—a top source of omega-3 fatty acids, particularly eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA). These long-chain fats help calm inflammation by supporting healthy blood vessels, improving cell membrane function and influencing immune signaling. A 3-ounce serving of cooked salmon provides over one gram of combined EPA and DHA, delivering a substantial anti-inflammatory boost.

Regularly including salmon or other fatty fish—like sardines, trout or herring—can support heart and brain health while helping to reduce inflammation over time. For most adults, eating seafood twice per week is an easy way to incorporate these benefits into everyday meals.

Shopping & Cooking Tips

Choose Mostly Whole Foods. Many anti-inflammatory compounds, especially in cranberries and pears, are concentrated in the skin—so fresh or frozen whole forms offer more benefits than juices or more processed versions.
Add Healthy Fats. Pair produce like pumpkin or kale with olive oil, avocado or nuts to boost absorption of fat-soluble antioxidants.
Buy Frozen Produce. Missed out on the fresh, seasonal produce? Not a problem. Frozen mushrooms, cranberries and kale are harvested at peak freshness and retain their nutrients, often for a fraction of the price. 
Look for Color. Deep reds, greens and oranges are signs of antioxidant-rich foods that help protect cells from inflammation.
Mix and Match. Combining several anti-inflammatory foods in one meal can boost their benefits. For example, try grilled salmon with kale or spinach and mushroom quiche.

Our Expert Take 

Fall is the perfect season for cozy, nourishing dishes. Many seasonal foods are not only delicious but also packed with nutrients and anti-inflammatory benefits, such as pumpkin, pears, cranberries, pears, kale and mushrooms. For maximum benefits, fill your plate with color and variety, letting these ingredients shine in simple, comforting meals. Fall never tasted so good—or felt so good for you.