Asadi-Pooya AA, Brigo F, Lattanzi S, Blumcke I. Adult epilepsy. Lancet. 2023;402(10399):412–24.
Fiest KM, Sauro KM, Wiebe S, Patten SB, Kwon CS, Dykeman J, et al. Prevalence and incidence of epilepsy: a systematic review and meta-analysis of international studies. Neurology. 2017;88(3):296–303.
Kwan P, Arzimanoglou A, Berg AT, Brodie MJ, Allen Hauser W, Mathern G, et al. Definition of drug resistant epilepsy: consensus proposal by the ad hoc task force of the ILAE commission on therapeutic strategies. Epilepsia. 2010;51(6):1069–77.
Mesraoua B, Brigo F, Lattanzi S, Abou-Khalil B, Al Hail H, Asadi-Pooya AA. Drug-resistant epilepsy: definition, pathophysiology, and management. J Neurol Sci. 2023;452:120766.
Engel J Jr, McDermott MP, Wiebe S, Langfitt JT, Stern JM, Dewar S, et al. Early surgical therapy for drug-resistant temporal lobe epilepsy: a randomized trial. JAMA. 2012;307(9):922–30.
Wiebe S, Blume WT, Girvin JP, Eliasziw M. A randomized, controlled trial of surgery for temporal-lobe epilepsy. N Engl J Med. 2001;345(5):311–8.
Spotnitz M, Ekanayake CD, Ostropolets A, McKhann GM, Choi H, Ottman R, et al. Use of recommended neurodiagnostic evaluation among patients with drug-resistant epilepsy. JAMA Neurol. 2024;81(5):499–506.
Theodore WH, Fisher RS. Brain stimulation for epilepsy. Lancet Neurol. 2004;3(2):111–8.
Stypulkowski PH, Stanslaski SR, Jensen RM, Denison TJ, Giftakis JE. Brain stimulation for epilepsy–local and remote modulation of network excitability. Brain Stimul. 2014;7(3):350–8.
Haneef Z, Skrehot HC. Neurostimulation in generalized epilepsy: a systematic review and meta-analysis. Epilepsia. 2023;64(4):811–20.
Peltola J, Colon AJ, Pimentel J, Coenen VA, Gil-Nagel A, Gonçalves Ferreira A, et al. Deep brain stimulation of the anterior nucleus of the thalamus in drug-resistant epilepsy in the MORE multicenter patient registry. Neurology. 2023;100(18):e1852-65.
Fisher R, Salanova V, Witt T, Worth R, Henry T, Gross R, et al. Electrical stimulation of the anterior nucleus of thalamus for treatment of refractory epilepsy. Epilepsia. 2010;51(5):899–908.
Salanova V, Witt T, Worth R, Henry TR, Gross RE, Nazzaro JM, et al. Long-term efficacy and safety of thalamic stimulation for drug-resistant partial epilepsy. Neurology. 2015;84(10):1017–25.
Salanova V, Sperling MR, Gross RE, Irwin CP, Vollhaber JA, Giftakis JE, et al. The SANTÉ study at 10 years of follow-up: effectiveness, safety, and sudden unexpected death in epilepsy. Epilepsia. 2021;62(6):1306–17.
Herrman H, Egge A, Konglund AE, Ramm-Pettersen J, Dietrichs E, Taubøll E. Anterior thalamic deep brain stimulation in refractory epilepsy: a randomized, double-blinded study. Acta Neurol Scand. 2019;139(3):294–304.
Kerrigan JF, Litt B, Fisher RS, Cranstoun S, French JA, Blum DE, et al. Electrical stimulation of the anterior nucleus of the thalamus for the treatment of intractable epilepsy. Epilepsia. 2004;45(4):346–54.
Lee KJ, Shon YM, Cho CB. Long-term outcome of anterior thalamic nucleus stimulation for intractable epilepsy. Stereotact Funct Neurosurg. 2012;90(6):379–85.
Herrera ML, Suller-Marti A, Parrent A, MacDougall K, Burneo JG. Stimulation of the anterior nucleus of the thalamus for epilepsy: a Canadian experience. Can J Neurol Sci. 2021;48(4):469–78.
Kaufmann E, Bötzel K, Vollmar C, Mehrkens JH, Noachtar S. What have we learned from 8 years of deep brain stimulation of the anterior thalamic nucleus? Experiences and insights of a single center. J Neurosurg. 2021;135(2):619–28.
Ewert S, Plettig P, Li N, Chakravarty MM, Collins DL, Herrington TM, et al. Toward defining deep brain stimulation targets in MNI space: a subcortical atlas based on multimodal MRI, histology and structural connectivity. Neuroimage. 2018;170:271–82.
Möttönen T, Katisko J, Haapasalo J, Tähtinen T, Kiekara T, Kähärä V, et al. Defining the anterior nucleus of the thalamus (ANT) as a deep brain stimulation target in refractory epilepsy: delineation using 3 T MRI and intraoperative microelectrode recording. NeuroImage: Clinical. 2015;7:823–9.
Neudorfer C, Butenko K, Oxenford S, Rajamani N, Achtzehn J, Goede L, et al. Lead-dbs v3.0: mapping deep brain stimulation effects to local anatomy and global networks. Neuroimage. 2023;268:119862.
Fisher RS, Cross JH, D’Souza C, French JA, Haut SR, Higurashi N, et al. Instruction manual for the ILAE 2017 operational classification of seizure types. Epilepsia. 2017;58(4):531–42.
Cramer JA, Perrine K, Devinsky O, Bryant-Comstock L, Meador K, Hermann B. Development and cross-cultural translations of a 31-item quality of life in epilepsy inventory. Epilepsia. 1998;39(1):81–8.
Kaufmann E, Peltola J, Colon AJ, Lehtimäki K, Majtanik M, Mai JK, et al. Long-term evaluation of anterior thalamic deep brain stimulation for epilepsy in the European MORE registry. Epilepsia. 2024;65(8):2438–58.
Shlobin NA, Sander JW. Current principles in the management of drug-resistant epilepsy. CNS Drugs. 2022;36(6):555–68.
Ashkan K, Rogers P, Bergman H, Ughratdar I. Insights into the mechanisms of deep brain stimulation. Nat Rev Neurol. 2017;13(9):548–54.
Miocinovic S, Somayajula S, Chitnis S, Vitek JL. History, applications, and mechanisms of deep brain stimulation. JAMA Neurol. 2013;70(2):163–71.
Reich MM, Hsu J, Ferguson M, Schaper F, Joutsa J, Roothans J, et al. A brain network for deep brain stimulation induced cognitive decline in Parkinson’s disease. Brain. 2022;145(4):1410–21.
Moussawi K, Kim MJ, Baybayan S, Wood M, Mills KA. Deep brain stimulation effect on anterior pallidum reduces motor impulsivity in Parkinson’s disease. Brain Stimul. 2022;15(1):23–31.
Balint B, Mencacci NE, Valente EM, Pisani A, Rothwell J, Jankovic J, et al. Dystonia. Nat Rev Dis Primers. 2018;4(1):25.
Kaski D, Bronstein AM, Edwards MJ, Stone J. Cranial functional (psychogenic) movement disorders. Lancet Neurol. 2015;14(12):1196–205.
Okun MS. Deep-brain stimulation for Parkinson’s disease. N Engl J Med. 2013;368(5):483–4.
Aiello G, Ledergerber D, Dubcek T, Stieglitz L, Baumann C, Polanìa R, et al. Functional network dynamics between the anterior thalamus and the cortex in deep brain stimulation for epilepsy. Brain. 2023;146(11):4717–35.
Krishna V, King NK, Sammartino F, Strauss I, Andrade DM, Wennberg RA, et al. Anterior nucleus deep brain stimulation for refractory epilepsy: insights into patterns of seizure control and efficacious target. Neurosurgery. 2016;78(6):802–11.
Kay BP, DiFrancesco MW, Privitera MD, Gotman J, Holland SK, Szaflarski JP. Reduced default mode network connectivity in treatment-resistant idiopathic generalized epilepsy. Epilepsia. 2013;54(3):461–70.
Assis ZA, Sevick R. Association of transsynaptic degeneration of the Papez circuit with anterior thalamic encephalomalacia. JAMA Neurol. 2018;75(11):1437–8.
Schaper F, Plantinga BR, Colon AJ, Wagner GL, Boon P, Blom N, et al. Deep brain stimulation in epilepsy: a role for modulation of the mammillothalamic tract in seizure control? Neurosurgery. 2020;87(3):602–10.
Kim E, Ku J, Namkoong K, Lee W, Lee KS, Park JY, et al. Mammillothalamic functional connectivity and memory function in Wernicke’s encephalopathy. Brain. 2009;132(Pt 2):369–76.
Berkovic SF. Surgical treatment of temporal lobe epilepsy. J Neurol Neurosurg Psychiatry. 2002;73(5):470.
Hong SJ, Bernhardt BC, Schrader DS, Bernasconi N, Bernasconi A. Whole-brain MRI phenotyping in dysplasia-related frontal lobe epilepsy. Neurology. 2016;86(7):643–50.
Bonini F, McGonigal A, Trébuchon A, Gavaret M, Bartolomei F, Giusiano B, et al. Frontal lobe seizures: from clinical semiology to localization. Epilepsia. 2014;55(2):264–77.
Stypulkowski PH, Stanslaski SR, Giftakis JE. Modulation of hippocampal activity with fornix deep brain stimulation. Brain Stimul. 2017;10(6):1125–32.
Aggleton JP, Pralus A, Nelson AJ, Hornberger M. Thalamic pathology and memory loss in early Alzheimer’s disease: moving the focus from the medial temporal lobe to Papez circuit. Brain. 2016;139(Pt 7):1877–90.
Xu C, Qi L, Wang X, Schaper F, Wu D, Yu T, et al. Functional connectomic profile correlates with effective anterior thalamic stimulation for refractory epilepsy. Brain Stimul. 2023;16(5):1302–9.
Sherdil A, Chabardès S, David O, Piallat B. Coherence between the hippocampus and anterior thalamic nucleus as a tool to improve the effect of neurostimulation in temporal lobe epilepsy: an experimental study. Brain Stimul. 2020;13(6):1678–86.
Yu T, Wang X, Li Y, Zhang G, Worrell G, Chauvel P, et al. High-frequency stimulation of anterior nucleus of thalamus desynchronizes epileptic network in humans. Brain. 2018;141(9):2631–43.
Yang JC, Bullinger KL, Dickey AS, Karakis I, Alwaki A, Cabaniss BT, et al. Anterior nucleus of the thalamus deep brain stimulation vs temporal lobe responsive neurostimulation for temporal lobe epilepsy. Epilepsia. 2022;63(9):2290–300.
Wang Y, Shen Y, Cai X, Yu J, Chen C, Tan B, et al. Deep brain stimulation in the medial septum attenuates temporal lobe epilepsy via entrainment of hippocampal theta rhythm. CNS Neurosci Ther. 2021;27(5):577–86.
Scherer M, Milosevic L, Guggenberger R, Maus V, Naros G, Grimm F, et al. Desynchronization of temporal lobe theta-band activity during effective anterior thalamus deep brain stimulation in epilepsy. Neuroimage. 2020;218:116967.
Wolff M, Alcaraz F, Marchand AR, Coutureau E. Functional heterogeneity of the limbic thalamus: from hippocampal to cortical functions. Neurosci Biobehav Rev. 2015;54:120–30.
Marchesi O, Bonacchi R, Valsasina P, Rocca MA, Filippi M. Resting state effective connectivity abnormalities of the Papez circuit and cognitive performance in multiple sclerosis. Mol Psychiatry. 2022;27(9):3913–9.
Liu J, Yu T, Wu J, Pan Y, Tan Z, Liu R, et al. Anterior thalamic stimulation improves working memory precision judgments. Brain Stimul. 2021;14(5):1073–80.
Ríos AS, Oxenford S, Neudorfer C, Butenko K, Li N, Rajamani N, et al. Optimal deep brain stimulation sites and networks for stimulation of the fornix in Alzheimer’s disease. Nat Commun. 2022;13(1):7707.
Germann J, Elias GJB, Boutet A, Narang K, Neudorfer C, Horn A, et al. Brain structures and networks responsible for stimulation-induced memory flashbacks during forniceal deep brain stimulation for Alzheimer’s disease. Alzheimers Dement. 2021;17(5):777–87.