The Republic of Ireland have suffered a signifcant injury blow ahead of March’s World Cup play-offs after Burnley confirmed that midfielder Josh Cullen sustained a serious knee injury.

Cullen, who is club captain at the Premier League side, suffered the setback in Saturday’s 0-0 draw against Everton at Turf Moor.

Burnley said that he will face a “prolonged” spell on the sidelines, with the prognosis ruling him out of the World Cup play-off semi-final against Czechia on 26 March in Prague.

The 29-year-old’s lengthy lay-off represents a huge blow to Ireland manager Heimir Hallgrimsson’s plans, with Cullen having been a stalwart under the Icelandic coach and predecessor Stephen Kenny, amassing 47 senior caps to date.

“Josh Cullen sustained an anterior cruciate ligament injury in Saturday’s Premier League fixture against Everton,” Burnley said in a statement on Tuesday night.

“The Clarets skipper injured his right knee early in the second half of the goalless draw at Turf Moor.

“Scans on Monday confirmed Cullen sustained an ACL injury and he will undergo surgery.

“The Republic of Ireland international is now set for a prolonged period on the sidelines.

“Everyone at Burnley Football Club wishes Josh all the best for a successful and speedy recovery.”