Alzheimer’s plaques decline after CAR-T immune cell treatment in preclinical study
A novel CAR-T cell approach targets amyloid plaques in preclinical Alzheimer models, raising the possibility that engineered immune…
Dynamic viral markers predict treatment response in hepatitis B
Background and aims The rate of functional cure (HBsAg loss) remains unsatisfactory following pegylated interferon (PEG-IFN) treatment in…
Web-based cytometry atlas reveals immune signatures across pancreatic cancer treatments
Oncologists have achieved some immune system responses in patients with pancreatic cancers using various combinations of vaccines and…
Silica nanomatrix enhances immunotherapy for solid tumors
Cancer has long remained a leading cause of death worldwide and in Hong Kong, accounting for 30% of…
Epigenetic plasticity in germinal center B cells may help explain lymphoma origins
Immune cells called B cells make antibodies that fight off invading bacteria, viruses and other foreign substances. During…
Engineered extracellular vesicles enable antigen-specific regulatory T cell induction
A research team at the Nano Life Science Institute (WPI-NanoLSI) and the Faculty of Medicine at Kanazawa University…
Review highlights emerging role of tumor MHC-II in shaping cancer immunotherapy outcomes
Cancer immunotherapy has transformed cancer treatment, yet many patients experience limited or short-lived responses due to immune evasion,…
Dietary restriction boosts antitumour immunity by rewiring T cell metabolism
By elevating ketone-driven energy pathways inside CD8+ T cells, dietary restriction steers them away from exhaustion and toward…
Organ-on-a-chip system reveals how aging weakens vaccine-driven anti-cancer immunity
Dr. Vadim Jucaud’s lab at the Terasaki Institute has introduced a new organ-on-a-chip platform that recapitulates age-dependent immune…
Kimchi consumption strengthens antigen recognition and immune regulation
Amid concerns about the simultaneous spread of multiple respiratory diseases, such as colds and influenza, with the change…
Protein linked to cancer plays key role in wound healing
When doctors detect elevated levels of SerpinB3 in a blood test, it can signal that something is seriously…
Study identifies molecular brake that controls overactive killer T cells
“Why do immune cells that are supposed to eliminate viruses suddenly turn against our own body?” There are…