Engineered extracellular vesicles enable antigen-specific regulatory T cell induction
A research team at the Nano Life Science Institute (WPI-NanoLSI) and the Faculty of Medicine at Kanazawa University…
Review highlights emerging role of tumor MHC-II in shaping cancer immunotherapy outcomes
Cancer immunotherapy has transformed cancer treatment, yet many patients experience limited or short-lived responses due to immune evasion,…
Dietary restriction boosts antitumour immunity by rewiring T cell metabolism
By elevating ketone-driven energy pathways inside CD8+ T cells, dietary restriction steers them away from exhaustion and toward…
Organ-on-a-chip system reveals how aging weakens vaccine-driven anti-cancer immunity
Dr. Vadim Jucaud’s lab at the Terasaki Institute has introduced a new organ-on-a-chip platform that recapitulates age-dependent immune…
Kimchi consumption strengthens antigen recognition and immune regulation
Amid concerns about the simultaneous spread of multiple respiratory diseases, such as colds and influenza, with the change…
Protein linked to cancer plays key role in wound healing
When doctors detect elevated levels of SerpinB3 in a blood test, it can signal that something is seriously…
Study identifies molecular brake that controls overactive killer T cells
“Why do immune cells that are supposed to eliminate viruses suddenly turn against our own body?” There are…
precision DNA repair may hold clues for human aging
The bowhead whale’s remarkable lifespan and low cancer risk stem from a finely tuned DNA repair system driven…
Scripps Research professor wins $3.2 million grant to unravel the mysteries of type 1 diabetes
Luc Teyton, professor in the Department of Immunology and Microbiology at Scripps Research, has received a five-year, $3.2…
One shot to rule them all in the fight against H5 influenza
The immunological arms race between virus and vaccines may change in the future, at least for bird flu…
Combination strategy may optimize interferon-based therapy for chronic hepatitis B
Background and objectives Peginterferon-α treatment exhibits low rates of the serological conversion rate of hepatitis B e antigen…
Engineered CAR T cells show promise against solid tumors
Chimeric antigen receptor (CAR) T cell therapy, which uses a patient’s own immune cells to fight cancer, has…