Blood p-tau217 levels signal cognitive impairment risk years before symptoms emerge
A six-cohort analysis links higher baseline p-tau217 to rising 5- and 10-year risks, bringing presymptomatic risk models closer…
LIG1 loss reveals new treatment strategy for aggressive breast cancer
Loss of one copy of the DNA Ligase I (LIG1) gene in triple-negative breast cancers (TNBC) with TP53…
Weill Cornell Medicine receives federal grant to study new gene therapy for Alzheimer’s disease
The National Institute on Aging of the National Institutes of Health has awarded a five-year grant initially worth…
BCG vaccine may remodel the human brain’s immune environment
New research led by Mass General Brigham investigators suggests that the Bacillus Calmette-Guérin (BCG) vaccine – which is…
Alzheimer’s disease biomarkers predict rapid cognitive decline in very old adults
Cognitive decline in very old adults has been considered for decades to be an almost inevitable consequence of…
New biomarker predicts gastric cancer outcomes from CT scans
Researchers at the State University of Campinas (UNICAMP) in São Paulo, Brazil, have identified a new biomarker that…
Identifying the ages when Alzheimer’s biomarkers sharply change
New research pinpoints the ages when Alzheimer’s-related brain changes accelerate, offering critical clues to when screening may be…
Baby teeth show when metal exposure may affect brain development
A child’s earliest exposures may leave lasting biological signatures. This study shows how tiny layers in baby teeth…
Proteomics and AI bring earlier risk prediction into sharper focus
From Alzheimer’s risk to cardiovascular prediction, this review shows how protein profiling and AI could help detect disease…
Older adults show high willingness for Alzheimer’s blood tests
Northwestern University psychologist Andrea Russell sees older adults with early cognitive impairment riddled with anxiety. Some worry a missed word or…
New biomarker predicts prognosis and treatment response in colorectal cancer
Determining the presence of a protein in non-tumor cells within the cancer microenvironment could be one of the keys to establishing prognosis…
Study finds long COVID leaves a distinct immune signature in the blood
Blood tests revealed protein patterns tied to long COVID months after infection, while booster shots did not appear…