New polygenic risk scores improve prediction of metabolic disease outcomes
Type 2 diabetes (T2D) and obesity are metabolic conditions with many causes, including overlapping and distinct genetic features.…
HIQA to assess inclusion of breast density in screening programme
Assessment will consider whether it would be beneficial to measure, record, and notify women attending BreastCheck of their…
Puberty reshapes DNA to worsen or reverse insulin resistance
A longitudinal study shows that puberty may reprogram children’s epigenetic profiles in ways that track worsening or improving…
Gut bacteria patterns help predict insulin resistance in type 2 diabetes, study finds
A new study shows that gut microbiome signatures, analyzed through advanced machine learning, can help identify individuals with…
Tirzepatide shows dual benefits in sleep apnea trial improving metabolism and reducing inflammation
New clinical trial evidence suggests targeting both obesity and sleep-disordered breathing together may reshape cardiometabolic risk management in…
Global analysis reveals up to four in ten cancer cases could be prevented
Up to four in ten cancer cases worldwide could be prevented, according to a new global analysis from…
High BMI linked to vascular dementia risk
High body mass index (BMI) could cause a higher risk of vascular-related dementia (a combination of vascular +…
Depression links to chronic headaches through weight and diet, not physical activity alone
Large population data from Iran show that body weight and iron intake help statistically explain the depression–headache link,…
Maternal obesity raises childhood epilepsy and disability risks, new study shows
A national Korean cohort study reveals that elevated pre-pregnancy BMI independently increases childhood risks of epilepsy and intellectual…
Reclassifying wine intake reshapes the Mediterranean diet’s cognitive impact
Scoring wine as a benefit in Mediterranean diet tools may blur important diet–cognition patterns, while reverse scoring reveals…
Scientists uncover new obesity genes that reshape understanding of weight and disease risk
A global research team maps how rare and common gene variants jointly drive obesity and metabolic disease, offering…
Genetic inflammatory signature defines depression subtypes and treatment response
Researchers led by Prof. Alessandro Serretti at Kore University of Enna have identified a genetic inflammatory signature that…