Genetic mismatch identified as major risk factor in cord blood transplantation
A Japanese study of more than 7,400 patients has identified a genetic mismatch that sharply increases the risk…
Hypoxia rewires red blood cells to clear excess glucose
In a 2023 paper on hypoxia and glucose metabolism, our lab showed how organisms rewire their metabolism to…
Researchers find new way to halt leukemia stem cell growth
In a new study published in Nature Communications, a research team at the University of Oslo have examined…
AI tool could help identify life-threatening transplant complications
A powerful artificial intelligence (AI) tool could give clinicians a head start in identifying life-threatening complications after stem…
Newly Discovered Brain Pathway Triggers Weight Loss
Summary: Researchers have identified a powerful neural pathway that triggers the rapid loss of all body fat—including “stubborn”…
Engineered Listeria boosts innate immunity against cancer
After nearly 40 years of research on how Listeria bacteria manipulate our cells and battle our immune system…
New evidence shows hematopoietic cell transplantation offers durable relief for sickle cell disease
Patients who underwent hematopoietic cell transplantation for sickle cell disease saw high rates of survival without disease symptoms…
Scientists create first human-cell bone marrow model in lab
For the first time in bioengineering, researchers have successfully developed a realistic model of human bone marrow using…
Understanding thrombocytopenia in patients with portal hypertension and chronic liver disease
Chronic liver disease (CLD) and its advanced stage, cirrhosis, represent a significant global health burden, with portal hypertension…
Dysfunction in chromosome-stabilizing protein identified as a cause of deadly illnesses
New research from the University of Wisconsin–Madison reveals that dysfunction in a protein essential to maintaining stability in…
Hypoxia weakens the body’s infection defense by changing genetic material of neutrophils
Low oxygen levels in the blood can alter the genetic makeup of key immune cells, weakening the body’s…
UIC researchers discover an important cellular mechanism that drives aging
As our hairs go gray and our muscles weaken with age, our immune system also changes. In particular,…