Genetic tool turns soft cancer cells into immune targets
Researchers at the USC Viterbi School of Engineering and Keck School of Medicine of USC have engineered a remarkable genetic tool that…
New ultrasound technique breaches blood brain barrier to treat gliomas
In a promising sign for the potential of focused sound waves to improve care for brain tumors, UVA…
New biological feedback loop helps the immune system attack colorectal cancers
A subset of cancers, known as microsatellite instability (MSI) and deficient DNA mismatch repair (dMMR) cancers, are more…
New breast cancer classification system predicts immunotherapy response success
The advent of immune checkpoint inhibitors (ICIs) has marked a paradigm shift in cancer treatment, yet a significant…
Dual-target CAR-T therapy shows promise against aggressive brain tumors
Researchers at McMaster University have developed a new cancer immunotherapy strategy that can simultaneously attack deadly brain tumors…
Researchers develop pH and redox-sensitive systems to reduce immunotherapy toxicity
Although cancer immunotherapy has transformed treatment by harnessing the immune system to eliminate tumors, only a small subset…
Mitochondrial activity keeps dendritic cells ready to fight disease
Researchers at the Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC) show that active mitochondria maintain dendritic cells,…
New insights highlight multifaceted roles of CD4+ T cells in tumor immunity
For decades, cancer immunotherapy has focused primarily on CD8+ cytotoxic T lymphocytes as the main executors of tumor…
Microbial ecosystems influence success of cancer checkpoint immunotherapy
Immune checkpoint inhibitors targeting PD-1 and PD-L1 have revolutionized cancer therapy, delivering long-term survival benefits in several malignancies.…
Study shows DHPS enzyme controls macrophage maturation across multiple organs
A new study led by researchers at the Johns Hopkins Kimmel Cancer Center, its Bloomberg~Kimmel Institute for Cancer Immunotherapy and the Johns…
Novel degraders show promise in preclinical studies
Cancer cells employ a variety of strategies to evade the immune system, and modern immunotherapies aim precisely at…
New study suggests a way to rejuvenate the immune system | MIT News
As people age, their immune system function declines. T cell populations become smaller and can’t react to pathogens…