Modeling heterogeneity in single-cell perturbation states enhances detection of response eQTLs
Cohorts We used published data (GEO accession no. GSE162632) to study the effect of 12 h of ex vivo…
Advocate and cancer survivor Lainie Jones dies at 41 in Fort Lauderdale
Lainie Jones believed in the power of being early. She credited early detection as the reason she survived…
Association of genetic variants in m1A modification core genes and neuroblastoma risk | BMC Cancer
Park JR, Kreissman SG, London WB, Naranjo A, Cohn SL, Hogarty MD, et al. Effect of tandem autologous…
Redefining cellular reprogramming with advanced genomic technologies
Briggs, R. & King, T. J. Transplantation of living nuclei from blastula cells into enucleated Frogs’ eggs. Proc.…
Digital and AI-assisted multimodal supportive care, combining physical activity, nutrition, and pain management during chemotherapy for advanced pancreatic cancer patients: study protocol of the European multicenter randomized controlled trial of the RELEVIUM project | BMC Cancer
Kamisawa T, Wood LD, Itoi T, Takaori K. Pancreatic cancer. Lancet. 2016;388(10039):73–85. Article PubMed Google Scholar Halbrook CJ,…
Characterization of induced cohesin loop extrusion trajectories in living cells
Experiments performed in this study did not require ethics board approval. Cell culture HAP1 cells were cultured in…
Meta-analysis reveals differences in somatic alterations by genetic ancestry across common cancers
Genetic ancestry is a quantitative measure of inherited genetic variation and correlates with human migration patterns1. It contributes…
Green-synthesized MnFeâ‚‚Oâ‚„/GO nanocomposites: structural characterization, cytotoxicity, and potential for targeted cervical cancer therapy | Cancer Cell International
FT-IR analysis The FTIR spectra were analyzed to determine the chemical functional groups present in MnFeâ‚‚Oâ‚„ NPs synthesized…
Association between triglyceride-glucose index and pathological invasiveness of lung adenocarcinoma in patients with solitary ground-glass nodules: a cross-sectional study | BMC Cancer
In this retrospective analysis of 278 individuals with solitary pGGNs pathologically verified as lung adenocarcinoma following surgery, an…
Population-scale gene-based analysis of whole-genome sequencing provides insights into metabolic health
Ethics Our research complies with all relevant ethical regulations. All studies included in this research were approved by…
Nucleotide dependency analysis of genomic language models detects functional elements
SpeciesLM training For SpeciesLM metazoa, we obtained metazoan genomes comprising 494 different species from the Ensembl 110 database36.…
Forensic genetics in the omics era
Jeffreys, A. J., Wilson, V. & Thein, S. L. Individual-specific ‘fingerprints’ of human DNA. Nature 316, 76–79 (1985).…