Childhood stress may lead to digestive issues later in life
Early life stress may lead to digestive issues later in life, driven by changes in the gut and…
Fred Hutch collaboration reveals molecular vulnerability in rare childhood brain cancer
When broken strands of DNA get repaired improperly, they can stitch together in new “Frankengene” fusions that can…
Study reveals how disordered proteins function without stable structure
A new LMU study shows how proteins function reliably even without a stable 3D structure – and the…
Vitamin B2 metabolism helps cancer cells resist ferroptosis
A lack of vitamin B2 makes tumor cells more susceptible to a unique form of cell death. This…
New insights highlight multifaceted roles of CD4+ T cells in tumor immunity
For decades, cancer immunotherapy has focused primarily on CD8+ cytotoxic T lymphocytes as the main executors of tumor…
CSF1R T567M mutation induces microglial dysfunction and synaptic impairment in patient iPSC-derived cerebral organoids of CSF1R-related disorder
Ayrignac X, Carra-Dalliere C, Codjia P, Mouzat K, Castelnovo G, Ellie E, et al. Evaluation of CSF1R-related adult…
Stilbenoid gaylussacin modulates particulate matter-induced chromatin remodeling in macrophages to suppress chronic obstructive pulmonary disease
Chronic obstructive pulmonary disease (COPD), a leading cause of mortality worldwide, is characterized by chronic bronchitis and emphysema.1…
Asymmetric division rejuvenates stem cell lineages
You have full access to this article via your institution. Mouse embryonic stem cells maintain lineage immortality through…
Engineered Listeria boosts innate immunity against cancer
After nearly 40 years of research on how Listeria bacteria manipulate our cells and battle our immune system…
Power of Tiny Molecular ‘Flycatcher’ Surprises Through Disorder
BYLINE: Jenny Green Newswise — For decades, scientists assumed that order drives efficiency. Yet in the bustling machinery…
Why cancer can come back years later — and how to stop it
When Lisa Dutton was declared free of breast cancer in 2017, she took a moment to celebrate with…
Epigenetic plasticity in germinal center B cells may help explain lymphoma origins
Immune cells called B cells make antibodies that fight off invading bacteria, viruses and other foreign substances. During…