Tumor microenvironment drives resistance to ferroptosis in pancreatic cancer
Tumors driven by cancer-driving KRAS mutations are often susceptible to ferroptosis, a type of cell death that can…
Vitamin B2 metabolism helps cancer cells resist ferroptosis
A lack of vitamin B2 makes tumor cells more susceptible to a unique form of cell death. This…
Chlamydia pneumoniae found in the eye may aggravate Alzheimer’s disease
Chlamydia pneumoniae—a common bacterium that causes pneumonia and sinus infections—can linger in the eye and brain for years…
Dual pathways found for centromere specification, ensuring accurate chromosome segregation
Despite the immense amount of genetic material present in each cell, around three billion base pairs in humans,…
Study reveals a therapeutic vulnerability in aggressive subtype of triple-negative breast cancer
Dec 26 2025 A new study published today in Science Translational Medicine by researchers at The University of…
Reframing the role of MCL1 in cancer signaling and metabolism
A study by the Mildred Scheel Early Career Center group led by Dr. Mohamed Elgendy at the TUD…
Novel antibody suppresses primary tumor growth and spread of triple-negative breast cancer
Triple-negative breast cancer (TNBC) is one of the most aggressive and treatment-resistant forms of breast cancer. It grows…
Bacterial enzyme linked to heart complications in pneumonia
Pneumonia is a disease that burdens the healthcare system with more that 1.2 million emergency room visits each…
AR3-based optogenetic strategy shows high efficacy in inducing apoptosis and antitumor effects
One of the hallmarks of cancer cells is their ability to evade apoptosis, or programmed cell death, through…
Innate immunity and metabolic stress drive a unique form of cell death
In several disease conditions, including infections and cancers, innate immune activation and nutrient scarcity occur together. A study…
Inflammation control can protect against AMD-like retinal damage
University of Minnesota Medical School researchers have shown that reducing chronic inflammation can significantly protect against age-related macular…
Innovative research reveals FGD3 as a key player in breast cancer cell death
A naturally occurring protein that tends to be expressed at higher levels in breast cancer cells boosts the…