Novel antibody suppresses primary tumor growth and spread of triple-negative breast cancer
Triple-negative breast cancer (TNBC) is one of the most aggressive and treatment-resistant forms of breast cancer. It grows…
Bacterial enzyme linked to heart complications in pneumonia
Pneumonia is a disease that burdens the healthcare system with more that 1.2 million emergency room visits each…
AR3-based optogenetic strategy shows high efficacy in inducing apoptosis and antitumor effects
One of the hallmarks of cancer cells is their ability to evade apoptosis, or programmed cell death, through…
Innate immunity and metabolic stress drive a unique form of cell death
In several disease conditions, including infections and cancers, innate immune activation and nutrient scarcity occur together. A study…
Inflammation control can protect against AMD-like retinal damage
University of Minnesota Medical School researchers have shown that reducing chronic inflammation can significantly protect against age-related macular…
Innovative research reveals FGD3 as a key player in breast cancer cell death
A naturally occurring protein that tends to be expressed at higher levels in breast cancer cells boosts the…
Study uncovers new mechanism for chromosome congression during mitosis
A research team from The University of Osaka, in collaboration with the Massachusetts Institute of Technology, has uncovered…
Lactate and lactylation drive metabolic, epigenetic reprogramming in gynecological cancers
Lactate, once considered a metabolic waste product, is now recognized as a key regulator of cellular homeostasis and…
Researchers develop a novel approach to monitor CD8⁺ T cell activity over time
The ability of immune cells-particularly CD8+ T cells-to launch a rapid burst of proliferation inside tumors is key…
Digital twin of lung cancer cell offers new insights into tumor growth and treatment
An enhanced computer model is now helping to provide fresh insights into cancer-cell growth and how it can…
Loss of key Y chromosome gene causes infertility in male mice
In a new study conducted at the University of Hawaiʻi at Mānoa, researchers from the John A. Burns…
Genetic mutation in some East Asians linked to aldehyde storm and increased liver disease risk
Researchers have identified the mechanism by which a common genetic mutation increases liver disease risk. Their findings suggest…