Mitochondrial rewiring may explain why orthoflaviviruses harm humans but persist in mosquitoes
From mitochondrial fragmentation to antioxidant defenses, researchers reveal how the same viruses can drive cellular damage in vertebrates…
Breast cancer co-opts the immune system to attract nerves that fuel tumor growth
New research from the University of Oklahoma demonstrates how an aggressive form of breast cancer co-opts the body’s…
Accumulation of somatic mutations drives vascular damage in people with progeria
Hutchinson-Gilford progeria syndrome (HGPS) is a genetic disorder that causes remarkable premature aging. Most patients die during their…
New biological feedback loop helps the immune system attack colorectal cancers
A subset of cancers, known as microsatellite instability (MSI) and deficient DNA mismatch repair (dMMR) cancers, are more…
Experimental compound BA-101 overcomes chemotherapy resistance in glioblastoma
Scientists have identified a promising new strategy to tackle one of the biggest obstacles in treating glioblastoma, one…
SLC7A11 deficiency exacerbates systemic lupus erythematosus by inducing instability and ferroptosis in regulatory T cells
Systemic lupus erythematosus (SLE) is an autoimmune disease posing a significant threat to human health. Regulatory T cells…
Developing brain cells routinely repair severe DNA damage during migration
Newborn nerve cells must squeeze through crowded, narrow spaces-through dense tissue, past other cells, between fibers-to reach the…
Study identifies new therapeutic candidate for KRAS-driven pancreatic cancer
A new research paper was published in Volume 17 of Oncotarget on June 3, 2026, titled “The anticancer effects of PCAIs…
AI-designed molecular switch uses caffeine to control engineered cells
For many of us, a warm cup of coffee is how we start our day. For Texas A&M…
Chromosome abnormalities may help cancer cells resist treatment and spread
A new study led by NYU Langone Health researchers found that cancer cells are better able to resist…
Exploiting a new weakness in ‘zombie-like’ cells to treat senescence-associated diseases
A new set of drugs exploit a recently-revealed weakness in ‘zombie-like’ – or senescent – cells that could lead to new treatments for cancer and age-associated diseases. The study from the…
APC-deficient cancer cells rely on single enzyme for survival
A newly published study reports that APC-deficient cancer cells may depend on a single metabolic enzyme for survival,…