Cancer-linked mutations in the brain cells may drive Alzheimer’s disease
As the body ages, cells naturally accumulate dozens of genetic mutations each year. New research from Boston Children’s…
Epigenome proteins shape dynamic gene expression beyond simple on-off
A new study finds the proteins responsible for controlling which genes are expressed in a genome do more…
Stem cell model recreates early human embryo with yolk sac
For the first time, a stem cell model has produced a structure resembling an early human embryo with…
Exploring water content in cells: A new measurement method
In this interview, News Medical-Life Sciences speaks with Teemu Miettinen, cell biologist at the Massachusetts Institute of Technology,…
Study reveals the physics behind neural tube closure in embryos
In about one out of every 1,000 pregnancies, the neural tube, a key nervous system structure, fails to close…
APC-deficient cancer cells rely on single enzyme for survival
A newly published study reports that APC-deficient cancer cells may depend on a single metabolic enzyme for survival,…
Targeting glutamine metabolism enhances CAR-macrophage cancer therapy
Tumor-associated macrophages (TAMs) within the tumor microenvironment (TME) exhibit significant metabolic dysregulation, which impairs their antitumor function. Specifically,…
New study reveals CRISPR enzyme that responds to human DNA methylation
Cancer cells excel at evading detection, but subtle chemical differences set them apart from healthy cells. Now, a…
Researchers discover how cell membrane composition drives cancer proliferation
Cells are enveloped by a lipid membrane that gives them structure and provides a barrier between the cell…
Scientists find unexpected immune pathways for mRNA cancer vaccines
The advent of mRNA vaccines against SARS-CoV-2 in 2020 changed the course of the COVID-19 pandemic. Now, the…
High-resolution study maps molecular differences across six human cortical regions
A new analysis of individual brain cells across several human brain regions reveals subtle but widespread differences in…
Hidden viral reservoirs in tonsils may explain school-year respiratory outbreaks
A study conducted at the University of São Paulo (USP) in Brazil reveals that tissues such as the…