Study explains why current BET inhibitors fail in cancer treatment
For over a decade, a class of drugs called BET inhibitors has been tested in cancer trials with…
Why early-onset cancers are rising and how researchers plan to stop them
Early-onset cancers are reshaping the cancer landscape, and this Cell Perspective lays out how researchers could uncover hidden…
Study outlines principles for using CAR immunotherapies to treat neurodegenerative diseases
A UAB research team defines the criteria that CAR immunotherapies for neurodegenerative diseases must meet to advance both conceptually…
Study reveals how tau tangles spread from one brain region to another in Alzheimer’s
Alzheimer’s disease is a progressive neurodegenerative disorder that slowly impairs memory, affects thinking skills, and eventually interferes with…
New blood test spots four cancers and other diseases by stripping away healthy DNA noise
By cutting through the overwhelming background of healthy blood DNA, MethylScan gives clinicians a clearer view of cancer,…
New blood biomarker improves cancer risk detection in people with Lynch Syndrome
Researchers at The University of Texas MD Anderson Cancer Center have discovered a new blood-based biomarker that can…
New method identifies key proteins that trigger harmful immune responses
Mayo Clinic researchers have developed a new method to identify which proteins are most likely to trigger an…
Novel mucosal vaccine offers broad protection against diverse influenza viruses
A novel vaccine platform has been developed to induce broad, protective immunity against numerous influenza virus infections, showing…
Researchers uncover a chain of molecular events behind early brain changes in Alzheimer’s
For the millions of people who carry the gene APOE4, the strongest known genetic risk factor for Alzheimer’s…
Tumor microenvironment drives resistance to ferroptosis in pancreatic cancer
Tumors driven by cancer-driving KRAS mutations are often susceptible to ferroptosis, a type of cell death that can…
A new global collaboration to expand patient-derived stem cell models and accelerate treatments
A new global initiative launched today aims to close a critical gap in ALS/MND drug discovery – current…
How could bisphenol A raise depression risk? Study identifies six key molecular targets
Researchers combined genetic epidemiology, transcriptomics, molecular docking, and mouse experiments to show how a common endocrine-disrupting chemical may…