Mitochondrial gene RTN4IP1 drives triple-negative breast cancer metastasis
Triple-negative breast cancer accounts for approximately 15% of all breast cancer cases. It is characterized by the absence…
Molecular mapping reveals hidden cellular programs in heart transplant rejection
A new study that explores gene expression during heart transplant rejection marks a step forward for precision medicine…
Genetic tool turns soft cancer cells into immune targets
Researchers at the USC Viterbi School of Engineering and Keck School of Medicine of USC have engineered a remarkable genetic tool that…
Scientists identify parasite-specific protein linked to chronic Toxoplasma infections
Toxoplasma gondii, or Toxoplasma, is a parasite that infects hundreds of millions of people around the world. Although…
Why pulses could play a bigger role in healthy and sustainable diets
From feeding beneficial gut microbes to improving selected metabolic markers, pulses combine nutrient density with sustainability, but researchers…
Early-life stress rewires brain epigenetics to heighten sensitivity to future stress
Mouse experiments reveal how early-life stress may leave a lasting epigenetic imprint in dopamine-related brain circuitry, priming molecular,…
Scientists create single-cell atlas of spinal neurons involved in motor coordination
Scientists at St. Jude Children’s Research Hospital created a single-cell atlas of a key class of spinal neurons…
Natural hormone activates brain-to-liver signaling pathway to suppress liver inflammation
Researchers at McMaster University have discovered that a naturally occurring hormone best known for suppressing appetite and promoting weight…
New protein blueprint opens door for targeted Parkinson’s disease therapies
Researchers at Weill Cornell Medicine have uncovered how a key Parkinson’s protein called LRRK2 shifts between inactive and…
New human genome benchmark captures both parental copies with near-perfect accuracy
By capturing both inherited chromosome sets and reaching genomic regions missed by conventional benchmarks, T2T-HG002 could help shift…
PRDM16 regulates the balance between proliferation and maturation in human cardiomyocytes
Understanding how heart muscle cells stop dividing and acquire the characteristics needed to sustain lifelong cardiac function remains…
Thinning cancer cells’ sugar coating could expose tumors to immune attack
Like spies evading detection through being masters of disguise, many cancer cells are adorned with a copious coat…