New polygenic risk scores improve prediction of metabolic disease outcomes
Type 2 diabetes (T2D) and obesity are metabolic conditions with many causes, including overlapping and distinct genetic features.…
New CRISPR technique boosts mitochondrial function to treat heart failure
After a heart attack, the heart struggles to recoup and maintain energy. One third of patients develop heart…
New strategy targets Porphyromonas gingivalis without harming healthy microbes
For years, treating gum disease has meant scraping away plaque, cutting out damaged tissue or turning to antibiotics…
Chronic inflammation shapes cancer progression and immunotherapy response
Chronic inflammation is both a driver and suppressor of cancer depending on context. Key players-NF-κB, IL-6, STAT3, TAMs,…
New diagnostic framework addresses challenges of rapidly-mutating RNA viruses
The rapid evolutionary dynamics of RNA viruses, driven by high mutation rates and the consequent formation of complex…
ERC Proof of Concept grant supports promising CRISPR-based cancer treatment research
Microbiologist John van der Oost of Wageningen University & Research (WUR) has received an ERC Proof of Concept…
AI‑Designed Anti‑CRISPRs Enable Rapid Cas13 Inhibition
Credit: Meletios Verras/Getty Images Last year’s landmark case of “Baby KJ”—the first patient to receive a personalized CRISPR‑based…
A safer gene-editing tool shows promise for transthyretin amyloidosis treatment
Genetic disorders occur due to alterations in the primary genetic material, deoxyribonucleic acid (DNA), of an organism. Transthyretin…
A precise tool to halt viral protein production
Across all domains of life, immune defenses foil invading viruses by making it impossible for the viruses to…
Engineering muscle stem cells for sustainable cultured meat production
The production of cultured meat depends on the isolation, expansion, and differentiation of animal stem cells into edible…
DeepSeek’s Liang Wenfeng makes the cut in top 10 ‘people who shaped science in 2025’
The Nature’s 10 profile of Liang recognised the disruption caused in January by the release of DeepSeek-R1, a…
DeepSeek’s Liang Wenfeng makes the cut in top 10 ‘people who shaped science in 2025’
The Nature’s 10 profile of Liang recognised the disruption caused in January by the release of DeepSeek-R1, a…