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Browsing Tag

Cytokines

8 posts
HHealth
Environmental insults reduce gut resilience and initiate convergent mechanisms that drive Parkinson’s disease. A lifetime of environmental insults (including Western diets and food additives, nano- and microplastics, pesticides and herbicides, industrial solvents, and air pollution) act on the intestinal microbiome and barrier. These exposures promote microbiota dysbiosis, disrupt tight junctions, and erode the mucus layer, collectively reducing gut resilience. Once this peripheral defense is compromised, several mechanistic pathways propagate pathology to the brain: (a) amyloid seeding by bacterial functional amyloids, (b) maladaptive T cell education and autoimmune responses, (c) microbiome-driven metabolic shifts that generate neurotoxic metabolites and reduce short-chain fatty acids, and (d) systemic inflammatory amplification. Together, these processes lower the threshold for α-syn misfolding, neuroinflammation, and neurodegeneration.
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Researchers propose that Parkinson’s disease may start in the gut, not the brain

  • March 6, 2026
Scientists propose that Parkinson’s disease may begin far from the brain, where environmental toxins, microbiome disruption, and intestinal…
HHealth
Review: Zinc: A metallic shield against cardiac inflammation. Image Credit: Cagkan Sayin / Shutterstock
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How zinc deficiency could worsen heart inflammation and what that means for patients

  • March 2, 2026
New research suggests that zinc does far more than support immunity, revealing intricate molecular switches that may influence…
HHealth
NYU Langone strengthens world-leading GI cancer program with renowned leaders
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Chronic inflammation shapes cancer progression and immunotherapy response

  • February 16, 2026
Chronic inflammation is both a driver and suppressor of cancer depending on context. Key players-NF-κB, IL-6, STAT3, TAMs,…
HHealth
Study: Emerging Roles of Modern Lifestyle Factors in Microbiome Stability and Functionality. Image Credit: Kateryna Kon / Shutterstock
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How modern lifestyles reprogram the gut microbiome and shape disease risk

  • January 28, 2026
From jet lag and poor sleep to exercise and chronic stress, this review unpacks how everyday lifestyle factors…
HHealth
Researchers unravel why mRNA-based vaccines for COVID-19 can cause heart damage
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Researchers unravel why mRNA-based vaccines for COVID-19 can cause heart damage

  • December 10, 2025
Stanford Medicine investigators have unearthed the biological process by which mRNA-based vaccines for COVID-19 can cause heart damage…
HHealth
Too sick to socialize: How the brain and immune system promote staying in bed | MIT News
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Too sick to socialize: How the brain and immune system promote staying in bed | MIT News

  • December 9, 2025
“I just can’t make it tonight. You have fun without me.” Across much of the animal kingdom, when…
HHealth
Study: SARS-CoV-2 mRNA vaccines sensitize tumours to immune checkpoint blockade. Image Credit: KwangSoo Kim / Shutterstock
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How COVID mRNA vaccines may make cancer treatments more effective

  • October 24, 2025
A new study reveals that SARS-CoV-2 mRNA vaccines can amplify immune checkpoint therapy in lung and skin cancers…
HHealth
Homemade Greek Yogurt in bowl
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Greek yogurt after exercise lowers inflammation more than carbs

  • September 25, 2025
Researchers discovered that young men who ate Greek yogurt after training showed lower levels of inflammation than those…
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