Brain organoids reveal mutation-specific insights for Rett syndrome
Though many studies approach the developmental disorder Rett syndrome as a single condition arising from general loss of…
Vibrio cholerae acquires antiviral defenses through horizontal gene transfer
Like most bacteria, Vibrio cholerae lives under constant attack from viruses. To survive, bacteria equip themselves with antiviral…
Study explains why current BET inhibitors fail in cancer treatment
For over a decade, a class of drugs called BET inhibitors has been tested in cancer trials with…
New blood test spots four cancers and other diseases by stripping away healthy DNA noise
By cutting through the overwhelming background of healthy blood DNA, MethylScan gives clinicians a clearer view of cancer,…
New blood biomarker improves cancer risk detection in people with Lynch Syndrome
Researchers at The University of Texas MD Anderson Cancer Center have discovered a new blood-based biomarker that can…
Toxic RNA drives progressive heart damage in myotonic dystrophy
Myotonic dystrophy type 1 (DM1) is the most common cause of adult-onset muscular dystrophy, a genetic disorder that…
Blood pressure drug boosts effectiveness of cancer therapy
In a new Dartmouth Cancer Center (DCC) study led by clinical researcher Tyler J. Curiel, MD, MPH, FACP,…
Tricorder Tech: Protein Sequencing Advance Offers New Insights Into Life’s Foundations
DNA-encoded Edman degradation on magnetic beads. (A) Reaction scheme for barcoding PTC amino acids via DNA-encoded Edman degradation…
New approach developed to visualize proteins at unprecedented scale and sensitivity
Proteins, one of the smallest building blocks of life on Earth, hold promise for answering some of biology’s…
AlphaFold Database expands with millions of predicted protein complexes
A new collaboration between EMBL’s European Bioinformatics Institute (EMBL-EBI), Google DeepMind, NVIDIA, and Seoul National University has made…
DNA’s Building Blocks May Have Arrived from Space, Asteroid Ryugu Samples Suggest
Samples returned by JAXA’s Hayabusa-2 mission from the C-type asteroid (162173) Ryugu contain all five canonical nucleobases —…
Do Extreme Environments Shape Microbial Genomes?
Graphical abstract — University of Waterloo Evolutionary biologists have long known that DNA, the molecule that carries the…