New tumor organoids strengthen precision oncology research
Significant advances have been made in the development of patient-derived tumor “organoids” for preclinical research, in two new…
New ctDNA blood test improves personalized prostate cancer treatment
A noninvasive DNA blood test can identify metastatic castration-resistant prostate cancer (mCRPC) patients who are most likely to…
New portable strip test accurately detects mosquito-borne viruses
A research team has developed a multisite bridging-mediated lateral flow immunoassay (mbLFIA) that enables highly sensitive, portable detection…
Diet helps people lose weight regardless of genetic obesity risk
A six-month clinical trial found that people with a high genetic risk for obesity benefited just as much…
LIG1 loss reveals new treatment strategy for aggressive breast cancer
Loss of one copy of the DNA Ligase I (LIG1) gene in triple-negative breast cancers (TNBC) with TP53…
New biological feedback loop helps the immune system attack colorectal cancers
A subset of cancers, known as microsatellite instability (MSI) and deficient DNA mismatch repair (dMMR) cancers, are more…
Integrating gene signatures and multi omics improves liver cancer treatment
Hepatocellular carcinoma (HCC) remains highly fatal due to late diagnosis and scarce early biomarkers. Multi‑omics and liquid biopsy…
Genes follow a random switching principle, yet remain precise on average
Inside the cell nucleus, genes must be turned on and off with precision to regulate biological processes. The…
New therapy targets Hippo pathway to fight treatment-resistant acute myeloid leukemia
Researchers at The University of Texas MD Anderson Cancer Center have discovered that an investigational epigenetic therapy remained effective in treatment-resistant acute myeloid…
New viral library helps scientists study thousands of proteins
To prevent viruses from sickening or killing us – whether it’s an individual case of hepatitis B or…
New study explains how brain tumors evolve to resist treatment
A form of glioma, a type of brain cancer, tends to progress towards greater malignancy due to an…
Lung tumors hack the nervous system to cause severe cachexia
Cachexia is a condition in which patients affected by cancer or other chronic diseases become sick and lose…