Amyloid fibers help sperm deliver RNA to mouse embryos
A longstanding mystery about the genetic messages carried by sperm led researchers to investigate an unexpected component of…
DNA Typewriter Chronicles Cell Lineage of Mouse Embryo
A DNA ‘typewriter’ records the history of 1.3 million cells in an early mouse embryo, telling the tale…
Genetic discovery offers clues for repairing damaged neural connections
A new discovery by neuroscientists at Brown University’s Carney Institute for Brain Science challenges long-held beliefs in neurobiology…
PRDM16 regulates the balance between proliferation and maturation in human cardiomyocytes
Understanding how heart muscle cells stop dividing and acquire the characteristics needed to sustain lifelong cardiac function remains…
St. Jude scientists uncover regulatory mechanism for crucial developmental pathway
St. Jude Children’s Research Hospital scientists uncovered a regulatory mechanism for signaling of Sonic Hedgehog (SHH), a pathway…
Base Editing reveals Human Embryo Development ‘Master Gene’
For the first time, researchers have used a genome editing technique called base editing to identify a master…
Autophagy Decline in Older Moms Halts Embryo Development
Summary: Researchers unmasked a hidden metabolic mechanism that explains why advanced maternal age (AMA) impairs female fertility and…
China sends synthetic human embryos to space in first test of how life begins off Earth
China has launched a new experiment to see how the earliest stages of human development might unfold in…
UC Davis scientists identify protein key to male fertility
The causes of male infertility can be hard to diagnose, with many tests failing to detect genetic defects.…
Sperm RNA aging shift that may explain paternal age effects
A newly revealed “aging cliff” in sperm RNA marks a conserved molecular transition from youth to later life,…
New computational method reconstructs how cells decide their fate
Researchers from Kyushu University have developed an innovative computational method, called ddHodge, that can reconstruct the complex dynamics…
Study uncovers role of mechanical forces in human gastrulation
Only two weeks after fertilization, the first sign of the formation of the 3 axes of the human…