EVITA clinical trial evaluates oral vitamin C for pre-cancerous blood disorders
Vitamin C boosts the activity of cellular proteins called TET enzymes that help control which genes are turned…
Call for papers: Promises and challenges in the development of PROTACs for chromatin modifiers
Taylor & Francis is pleased to invite you to submit your work to an upcoming Article Collection exploring…
“Zombie” Cells Reveal a Surprising New Driver of Chronic Inflammation
Senescent cells may rely on more than immune signaling to sustain age-related inflammation. A mitochondrial pathway that alters…
Paternal sperm epigenetics may help explain early pregnancy loss
When a pregnancy ends early and unexplained, the search for answers usually begins with the mother. Lacey Luense,…
Cell proliferation gene plays a distinct role in cells that no longer proliferate
In a tale of identities as divergent as “The Prince and the Pauper,” a well-known cancer-causing gene also…
Early-life stress rewires brain epigenetics to heighten sensitivity to future stress
Mouse experiments reveal how early-life stress may leave a lasting epigenetic imprint in dopamine-related brain circuitry, priming molecular,…
Exhausted T cells balance graft tolerance and infection risk
A comprehensive new review examines the complex role of T cell exhaustion in organ transplantation, highlighting how this…
AI-powered blood test detects liver cancer across distinct populations
Researchers at the Johns Hopkins Kimmel Cancer Center validated an artificial intelligence (AI)-powered blood test that accurately detected liver cancer…
Identifying critical lysines in mammalian histone H3 with high-throughput CRISPR prime editing
Adapting prime editing for mammalian histone mutagenesis Mouse canonical histone H3 is encoded by nine H3.1 and three…
Study explains how leukemia creates inflammatory lung environments
Acute myeloid leukemia (AML) does more than infiltrate the lungs: it also transforms lung tissue to create an…
New Research Shows Vitamin B12 May Hold the Key to Healthy Aging
A new Cornell study suggests vitamin B12 plays a far broader role in human biology than previously understood,…
Penn engineers use AI to solve some of science’s most difficult math problems
A ripple tells you something happened, but not exactly what. That is the core problem behind a hard…