Artificial lung keeps patient alive after lung removal
By replacing both breathing and circulatory buffering, a novel artificial lung bought critical time after lung removal, revealed…
Updated newborn screening guidelines aim to improve cystic fibrosis detection
An updated report on cystic fibrosis (CF) from Ann & Robert H. Lurie Children’s Hospital of Chicago, in…
Preclinical study reveals potential new treatment for severe liver fibrosis
Researchers at McMaster University are leading preclinical studies into a novel drug candidate developed by Espervita Therapeutics that has the potential to prevent and reverse liver fibrosis – a dangerous, disease-induced build-up of…
Single-cell RNA-seq reveals FBLN7’s role in adipose tissue fibrosis
Fibrosis, resulting from excess extracellular matrix (ECM) deposition, is a feature of adipose tissue (AT) dysfunction and obesity-related insulin resistance.…
Enterprise Therapeutics publishes results of Phase 1 study of ETD001, a novel inhaled ENaC blocker for treatment of Cystic Fibrosis, in The Journal of Cystic Fibrosis
Enterprise Therapeutics Ltd (Enterprise), a biopharmaceutical company dedicated to the discovery and development of novel therapies to improve…
Blocking immune cell signals reduces scar tissue formation in wounds
Researchers at the University of Arizona uncovered a previously unknown population of circulating immune cells that play a…
New insights reveal how TCF and LEF proteins control Wnt signaling and disease progression
Researchers have unveiled the intricate molecular mechanisms governing TCF/LEF-mediated transcription in the canonical Wnt pathway, identifying these proteins…
Lab-grown organoid offers a platform to study how liver scarring develops
As chronic liver disease becomes more widespread, researchers at Science Tokyo have developed a lab-grown organoid that replicates…
New biofilm discovery may pave way to undermining antibiotic-resistant Pseudomonas
The bacterium known as Pseudomonas aeruginosa is an unwelcome visitor in the human body. Serious infections can result…
New gene-editing method can correct many disease-causing mutations in mammalian cells
Some genetic disorders-such as cystic fibrosis, hemophilia and Tay Sachs disease-involve many mutations in a person’s genome, often…
New study solves lung transplant rejection mystery
More than 50%Â of lung-transplant recipients experience a rejection of their new lung within five years of receiving it,…
Groundbreaking 3D dynamic cell co-culture models simulate MASLD progression
In a recent work published in BME Frontiers, a collaborative study by researchers from Griffith University, Queensland University…