Mitochondria and lysosomes work together to control regulatory T cell activation
Metabolism guides the activation states of regulatory T cells, the immune cells that prevent inappropriate activation of the…
Disruption of glial circadian rhythms linked to Alzheimer’s disease progression
Alzheimer’s disease is notorious for scrambling patients’ daily rhythms. Restless nights with little sleep and increased napping during…
Torino Identifies mRNA Isoforms in Disease-Related Gene Expression
Credit: libre de droit / Getty Images Different variants of a gene, known as isoforms, can be transcribed…
Torino Identifies mRNA Isoforms in Disease-Related Gene Expression
Credit: libre de droit / Getty Images Different variants of a gene, known as isoforms, can be transcribed…
Forensic genetics in the omics era
Jeffreys, A. J., Wilson, V. & Thein, S. L. Individual-specific ‘fingerprints’ of human DNA. Nature 316, 76–79 (1985).…
The genetic influence of sex on gene expression for blood in pigs | BMC Genomics
Data summary We collected 386 blood samples with matched genotype and gene expression data from the PigGTEx project…
Largest study of African American brain tissue reveals key Alzheimer gene activity
The prevalence of Alzheimer disease (AD) is approximately two times higher in African Americans (AA) compared to White/European-ancestry…
Second round of exercise boosts muscle growth in mice
New research offers potential good news for those who’ve lapsed at the gym. The study found that mice…
Lysosomal activity in worms linked to transgenerational extension of lifespan
In the Wang Lab, it’s not unusual for worms to live for a long time. HHMI Janelia Research…
Scientists study how nanoplastics transfer across generations
You can’t see nanoplastics with the naked eye, but they’re everywhere – including your body. Tinier than the…
AI Model Finds Gene Targets and Drug Combos to Reprogram Diseased Cells
Credit: FlashMovie/Getty Images Traditional drug discovery has often followed the “one drug, one target” paradigm—developing compounds against individual…
Autism Genes Could Have Conferred Evolutionary Benefit
Credit: KATERYNA KON/SCIENCE PHOTO LIBRARY/Getty Images Genes relating to autism spectrum disorder (ASD) could have conferred benefits during…