Alcohol impacts gene expression differently across brain regions
Erica Periandri and Gabor Egervari, from Washington University in St. Louis, led a study to explore how alcohol exposure in male mice influences gene expression…
New AI system maps gene expression across the whole body
Understanding gene expression within the body has been a boon for 21st century biology and therapeutics, but most…
Scientists identify common molecular program across multiple brain tumor types
Research uncovering the origin of pineoblastoma, a rare pediatric brain tumor, has also revealed a dependency across multiple…
Study sheds light on potential therapeutic strategies for post-traumatic osteoarthritis
Post-traumatic osteoarthritis often affects younger, active individuals and progresses quickly following ligament or cartilage injury. Chondrocytes, the sole…
New HIV-seq tool advances understanding of persistent viral reservoirs
For people living with human immunodeficiency virus (HIV), life-saving antiretroviral therapy keeps their HIV-infected immune cells from making…
New method isolates true transcription factor targets in tuberculosis bacteria
Inside every cell, thousands of molecular signals collide, overlap, and compensate, obscuring the true drivers of gene expression.…
Scientists put forward a new theory of brain development
Your brain begins as a single cell. When all is said and done, it will house an incredibly…
A multi-dimensional framework for establishing and managing a genomic newborn screening program
The above-described methodology resulted in a multi-dimensional framework for a gNBS program consisting of 18 screening criteria (Table 1)…
Study maps how NF-κB regulates gene expression in cells
To further the quantitative understanding of cellular decision making, Dr. Gregory Reeves and his team in the chemical engineering department…
NIH’s continued investment fuels TMJ pain research
Chronic pain is one of the most common health conditions worldwide. Back pain is the most frequently reported…
Researchers reveal why SuperAgers retain youthful brain cell signatures into their 80s
A multiomic atlas of the aging human hippocampus uncovers how epigenetic regulation of neural stem cells and immature…
Simple blood test measuring piRNAs may help better understand health and aging
Research in Aging Cell indicates that blood levels of particular small non-coding RNAs, which regulate gene expression, may…