Spaceflight research opens new avenues for studying rare pediatric diseases
Earth-based hiPSC models have transformed disease research but remain limited by cellular immaturity, a strong reliance on glycolysis…
New mathematical method maps gene roles across different species
Background Much of what we know about biology comes from animal models, particularly mice. Applying these insights to…
Novel gene rejuvenation therapy preserves cell identity while reversing age
Every organ and tissue progressively loses function and integrity as it ages. In fact, researchers have identified “hallmarks…
Advances in chemistry and delivery are taking oligonucleotide medicines beyond rare diseases
Decades of work on RNA targeting, chemical modification, and tissue-specific delivery are reshaping what programmable genetic medicines can…
Could a daily glass of orange juice support heart health? Study finds citrus compounds influence genes linked to blood vessel function
Naturally occurring compounds in orange juice regulated genes involved in the control of cardiovascular and blood vessel function,…
Genetic discovery offers clues for repairing damaged neural connections
A new discovery by neuroscientists at Brown University’s Carney Institute for Brain Science challenges long-held beliefs in neurobiology…
Eight-year study reveals how molecular aging scripts differ individually
Aging does not appear to follow the same molecular script for everyone, according to an eight-year study of…
Researchers map DNA’s physical code using large-scale simulations
Nearly every cell in the human body contains essentially the same genetic information, yet different cells activate different…
Sprint exercise sends a very different molecular signal through the body
Just minutes of all-out sprint work produced a striking surge in circulating proteins and metabolites, revealing how exercise…
Molecular mapping reveals hidden cellular programs in heart transplant rejection
A new study that explores gene expression during heart transplant rejection marks a step forward for precision medicine…
Early-life stress rewires brain epigenetics to heighten sensitivity to future stress
Mouse experiments reveal how early-life stress may leave a lasting epigenetic imprint in dopamine-related brain circuitry, priming molecular,…
Scientists create single-cell atlas of spinal neurons involved in motor coordination
Scientists at St. Jude Children’s Research Hospital created a single-cell atlas of a key class of spinal neurons…