Mitochondrial activity keeps dendritic cells ready to fight disease
Researchers at the Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC) show that active mitochondria maintain dendritic cells,…
New research reveals how parasites break out of host cells
Parasites are a major global health problem, underlying many human diseases worldwide. For example, Plasmodium falciparum, the parasite…
Brain organoids reveal mutation-specific insights for Rett syndrome
Though many studies approach the developmental disorder Rett syndrome as a single condition arising from general loss of…
Breakthrough blood test predicts kidney failure years before clinical symptoms
A new blood test can identify which individuals of African ancestry carrying high-risk APOL1 gene variants are most…
Alzheimer’s risk gene APOE4 impacts bone health in females
Scientists at the Buck Institute for Research on Aging, along with collaborators at UC San Francisco, have discovered…
Parents’ intake of sugar substitutes may influence offspring gut biology, study finds
A new mouse study suggests that sweeteners consumed by parents may reshape gut bacteria, microbial metabolites, and metabolic…
Scientists use whole exome sequencing to discover a new rare genetic disease
Scientists at Sanford Burnham Prebys Medical Discovery Institute and an international team of collaborators used a genetic sequencing…
“It Was Survival Mode”: The Lunar Mission That Nearly Ended in Disaster
Griffin: During entry, there’s what we call a blackout, which is when it gets so hot that you…
Vibrio cholerae acquires antiviral defenses through horizontal gene transfer
Like most bacteria, Vibrio cholerae lives under constant attack from viruses. To survive, bacteria equip themselves with antiviral…
Study explains why current BET inhibitors fail in cancer treatment
For over a decade, a class of drugs called BET inhibitors has been tested in cancer trials with…
Cola may quickly lower pH inside orthodontic clear aligners and shift oral bacteria within hours
A 24-hour microbiome study suggests that cola can rapidly disturb the aligner-tooth microenvironment, and that removing aligners before…
Toxic RNA drives progressive heart damage in myotonic dystrophy
Myotonic dystrophy type 1 (DM1) is the most common cause of adult-onset muscular dystrophy, a genetic disorder that…